Adenosine Monophosphate-Activated Protein Kinase Signal Transduction Pathways:Regulation Mechanism in Process of Cow Ketosis Occurrence and Development
DONG Jihong1, WU Jinjie1, WANG Xichun1, FENG Shibin1, DING Hongyan1, LIU Guowen2, LI Xinwei2, LI Xiaobing2, WANG Zhe2, LI Yu1
1. College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China; 2. College of Veterinary Medicine, Jilin University, Changchun 130062, China
Abstract：Cow ketosis is a common nutritional and metabolic disease during perinatal, which has caused tremendous losses to the dairy industry. Related energy metabolic hormones have undergone tremendous changes when ketosis occurs, mainly including glucagon and insulin. Adenosine monophosphate-activated protein kinase(AMPK) is considered to be an energy sensor, some energy metabolic hormones can cause changes of AMPK activity. This article focused on the role of glucagon and insulin in AMPK signal transduction pathways aimed at providing theoretical support for further research in cow ketosis.
董记红, 吴金节, 王希春, 冯士彬, 丁红研, 刘国文, 李心慰, 李小兵, 王哲, 李玉. 腺苷酸活化蛋白激酶信号转导通路在奶牛酮病发生和发展过程中的调控机制[J]. 动物营养学报, 2016, 28(4): 1035-1041.
DONG Jihong, WU Jinjie, WANG Xichun, FENG Shibin, DING Hongyan, LIU Guowen, LI Xinwei, LI Xiaobing, WANG Zhe, LI Yu. Adenosine Monophosphate-Activated Protein Kinase Signal Transduction Pathways:Regulation Mechanism in Process of Cow Ketosis Occurrence and Development. Chinese Journal of Animal Nutrition, 2016, 28(4): 1035-1041.
