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动物营养学报 2017, Vol. 29 Issue (9) :3035-3043    DOI: 10.3969/j.issn.1006-267x.2017.09.003
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代谢组学在奶牛营养与牛奶质量安全方面的研究进展
王倩1,2, 张养东1,2,3, 郑楠1,2,3, 李松励1,2,3, 文芳1,2,3, 赵圣国1,2,3, 王加启1,2,3
1. 中国农业科学院北京畜牧兽医研究所, 动物营养学国家重点实验室, 北京 100193;
2. 中国农业科学院北京畜牧兽医研究所, 农业部奶产品质量安全风险评估实验室(北京), 北京 100193;
3. 中国农业科学院北京畜牧兽医研究所, 农业部奶及奶制品监督检验测试中心(北京), 北京 100193
Research Progress on Metabolomics Application in Dairy Cow Nutrition and Milk Quality and Safety
WANG Qian1,2, ZHANG Yangdong1,2,3, ZHENG Nan1,2,3, LI Songli1,2,3, WEN Fang1,2,3, ZHAO Shengguo1,2,3, WANG Jiaqi1,2,3
1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
2. Laboratory of Quality and Safety Risk Assessment for Dairy Products of Ministry of Agriculture(Beijing), Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
3. Milk and Milk Products Inspection Center of Ministry of Agriculture(Beijing), Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China
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摘要 代谢组学是检测低分子质量(通常分子质量小于1 000 u)代谢物的变化,并以此来研究生物体受到病理/生理刺激或基因改变后所产生代谢产物的构成及其变化规律的学科。它是后基因时代发展起来的一门新的学科,是系统生物学的重要组成部分。代谢组学已经广泛应用于生理学、病理学、药理学、动物营养学、动物学和植物学等各个领域,但代谢组学在奶牛营养与牛奶质量安全研究中的应用还比较少。本文从代谢组学的基本概念、研究思路和方法等入手,综述了目前代谢组学在奶牛营养、疾病、热应激、牛奶质量与奶品安全中的应用。
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关键词代谢组学   奶牛   营养   牛奶   质量   安全     
Abstract: Metabolomics can detect changes of metabolites with trait of low molecular weight (usually less than 1 000 u). Based on this, it can be used to study the constituents and variation of the metabolites produced by stimulation of pathological and physiological infectors or gene change. It is a new subject that is developing in the post-genomic era, and is an important part of system biology. At present, it has been widely used in physiology, pathology, pharmacology, animal science, zoology, botany and other fields, but the researches on cow nutrition and milk safety and quality are still relatively less. Starting from basic concept, ideas and methods of metabolomics firstly, this article overviewed the current research on dairy cows' nutrition, disease, heat stress, milk quality and milk products safety by application of metabolomics.
Keywordsmetabolomics,   cow,   nutrition,   milk,   quality,   safety     
收稿日期: 2017-02-13;
基金资助:

现代农业产业技术体系专项资金(nycytx-04-01);公益性行业(农业)科研专项(201403071);中国农业科学院科技创新工程(ASTIP-IAS12)

通讯作者 张养东,副研究员,E-mail:yangdongzhang1982@163.com     Email: yangdongzhang1982@163.com
作者简介: 王倩(1977-),男,安徽滁州人,博士,研究方向为奶牛营养与饲料科学。E-mail:sousawang@163.com
引用本文:   
. 代谢组学在奶牛营养与牛奶质量安全方面的研究进展[J]. 动物营养学报, 2017,V29(9): 3035-3043
. Research Progress on Metabolomics Application in Dairy Cow Nutrition and Milk Quality and Safety[J]. Chinese Journal of Animal Nutrition, 2017,V29(9): 3035-3043.
链接本文:  
http://www.chinajan.com/CN/10.3969/j.issn.1006-267x.2017.09.003     或     http://www.chinajan.com/CN/Y2017/V29/I9/3035
 
[1] MILLER G D,JARVIS J K,MCBEAN L D.Handbook of dairy foods and nutrition[M].3rd ed.Boca Raton:CRC Press,2007.
[2] AULDIST M J,HUBBLE I B.Effects of mastitis on raw milk and dairy products[J].Australian Journal of Dairy Technology,1998,53(1):28-36.
[3] ELGERSMA A,TAMMINGA S,ELLEN G.Modifying milk composition through forage[J].Animal Feed Science and Technology,2006,131(3/4):207-225.
[4] GARNSWORTHY P C,MASSON L L,LOCK A L,et al.Variation of milk citrate with stage of lactation and de novo fatty acid synthesis in dairy cows[J].Journal of Dairy Science,2006,89(5):1604-1612.
[5] BIONAZ M,LOOR J J.Gene networks driving bovine milk fat synthesis during the lactation cycle[J].BMC Genomics,2008,9(1):366.
[6] WISHART D S,KNOX C,GUO A C,et al.HMDB:a knowledgebase for the human metabolome[J].Nucleic Acids Reserch,2009,37(S1):D603-D610.
[7] TANG H R,XIAO C N,WANG Y L.Important roles of the hyphenated HPLC-DAD-MS-SPE-NMR technique in metabonomics[J].Magnetic Resonance in Chemistry,2009,47(S1):S157-S162.
[8] YANG Y X,ZHENG N,ZHAO X W,et al.Metabolomic biomarkers identify differences in milk produced by Holstein cows and other minor dairy animals[J].Journal of Proteomics,2016,136:174-182.
[9] TIAN H,WANG J Q,ZHANG Y D,et al.Quantitative multiresidue analysis of antibiotics in milk and milk powder by ultra-performance liquid chromatography coupled to tandem quadrupole mass spectrometry[J].Journal of Chromatography B,2016,1033-1034:172-179.
[10] TIAN H,ZHENG N,WANG W Y,et al.Integrated metabolomics study of the milk of heat-stressed lactating dairy cows[J].Scientific Reports,2016,6:24208.
[11] VALERO E,VILLAMIEL M,MIRALLES B,et al.Changes in flavour and volatile components during storage of whole and skimmed UHT milk[J].Food Chemistry,2001,72(1):51-58.
[12] BELLOQUE J,CARRASCOSA A V,LÓPEZ-FANDIÑO R.Changes in phosphoglyceride composition during storage of ultrahigh-temperature milk,as assessed by 31P-nuclear magnetic resonance:possible involvement of thermoresistant microbial enzymes[J].Journal of Food Protection,2001,64:850-855.
[13] MARINCOLA F C,NOTO A,CABONI P,et al.A metabolomic study of preterm human and formula milk by high resolution NMR and GC/MS analysis:preliminary results[J].The Journal of Maternal-Fetal & Neonatal Medicine,2012,25(S5):62-67.
[14] ARTEGOITIA V M,MIDDLETON J L,HARTE F M,et al.Choline and choline metabolite patterns and associations in blood and milk during lactation in dairy cows[J].PLoS One,2014,9(8):e103412.
[15] PISANO M B,SCANO P,MURGIA A,et al.Metabolomics and microbiological profile of Italian mozzarella cheese produced with buffalo and cow milk[J].Food Chemistry,2016,192:618-624.
[16] HUMER E,KHOL-PARISINI A,METZLER-ZEBELI B U,et al.Alterations of the lipid metabolome in dairy cows experiencing excessive lipolysis early postpartum[J].PLoS One,2016,11(7):e0158633.
[17] SHARMA N,MAITI S K,ROY S.Role of Vitamin E in the control of mastitis in dairy cows[J].Veterinary Practitioner,2003,4(2):140-143.
[18] GRÖNLUND U,JOHANNISSON A,WALLER P K.Changes in blood and milk lymphocyte sub-populations during acute and chronic phases of Staphylococcus aureus induced bovine mastitis[J].Research in Veterinary Science,2006,80(2):147-154
[19] PETER A T,CLARK P W,VAN ROEKEL D E,et al.Temporal changes in metabolites of prostanoids in milk of heifers after intramammary in
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