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动物营养学报 2019, Vol. 31 Issue (3) :1009-1019    DOI: 10.3969/j.issn.1006-267x.2019.03.005
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植物化学物质生理调节作用关键信号通路研究进展
樊启文1,2,3, 陈芳1, 赵娜1, 魏金涛1
1. 湖北省农业科学院畜牧兽医研究所, 武汉 430064;
2. 动物胚胎工程及分子育种湖北省重点实验室, 武汉 430064;
3. 农业部畜禽细菌病防治制剂创制重点实验室, 武汉 430064
Research Advances in Key Signal Pathways Involved in Physiological Function Mediated by Phytochemicals
FAN Qiwen1,2,3, CHEN Fang1, ZHAO Na1, WEI Jintao1
1. Institute of Animal Science and Veterinary Medicine, Hubei Academy of Agricultural Sciences, Wuhan 430064, China;
2. Key Laboratory of Animal Embryo Engineering and Molecular Breeding of Hubei Province, Wuhan 430064, China;
3. Key Laboratory of Prevention and Control Agents for Animal Bacteriosis(Ministry of Agriculture), Wuhan 430064, China
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摘要 植物化学物质具有抗氧化、抗炎症、抗肿瘤和免疫增强等多种生理调节功能,这些生理调节功能有赖于细胞内存在的信号识别与传导通路,并最终经由相关关键转录因子及对应的效应基因的表达实现其调节功能。本文对植物化学物质在细胞内信号的识别与传导模式进行了归纳总结,并对参与其功能实现所经历的信号调节通路进行了综述。
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关键词植物化学物质   信号的识别与转导   信号通路   生理功能     
Abstract: Phytochemicals have many physiological functions such as anti-oxidation, anti-inflammatory, anti-tumor and immune enhancement. On the realization of these physiological functions, phytochemicals need to deliver the signals to cells which depends on the cellular signal recognition and transduction system. Ultimately, the expression of related key transcription factors and their effectors achieves the regulatory function. In this review, we summarized the patterns of the recognition and transduction for phytochemicals signal from extracellular to nuclear, and we also provided an overview of the signal pathways which phytochemicals involved in to realize their functions.
Keywordsphytochemicals,   signal recognition and conduction,   signal pathway,   physiological functions     
收稿日期: 2018-08-31;
基金资助:

大型规模化猪场无抗饲养关键技术研发(2017ABA058);湖北省农业科技创新中心项目(2016-620-000-001-028);国家自然科学基金项目(31702309);动物胚胎工程及分子育种湖北省重点实验室开放课题(KLAEMB-2018-06)

通讯作者 魏金涛,副研究员,E-mail:jintao001@163.com     Email: jintao001@163.com
作者简介: 樊启文(1988-),男,湖北仙桃人,博士,从事动物分子营养学与饲料资源开发利用研究。E-mail:qwfan11@sina.com
引用本文:   
. 植物化学物质生理调节作用关键信号通路研究进展[J]. 动物营养学报, 2019,V31(3): 1009-1019
. Research Advances in Key Signal Pathways Involved in Physiological Function Mediated by Phytochemicals[J]. Chinese Journal of Animal Nutrition, 2019,V31(3): 1009-1019.
链接本文:  
http://www.chinajan.com/CN/10.3969/j.issn.1006-267x.2019.03.005     或     http://www.chinajan.com/CN/Y2019/V31/I3/1009
 
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