Abstract：This experiment was conducted to study the effects of glucose tributyrate on growth performance, slaughter performance, serum biochemical indexes and intestinal mucosal morphology of broilers. One hundred and sixty 10-day-old healthy male Arbor Acres (AA) broilers were randomly divided into 4 groups with 4 replicates per group and 10 broilers per replicate. Broilers in the blank group were fed a basal diet, and the others in low, medium and high dose groups were fed the basal diet supplemented with 0.05%, 0.10% and 0.20% glucose tributyrate, respectively. The experiment lasted for 32 days. The results showed as follows:1) during 15 to 42 days of age, the average daily feed intake and average daily gain of low, medium and high dose groups were significantly higher than those of the blank group (P<0.05), and the ratio of feed to gain of low, medium and high dose groups was significantly lower than that of blank group (P<0.05). 2) At 28 days of age, the leg muscle percentage of high dose group was significantly higher than that of other groups (P<0.05); at 42 days of age, the leg muscle percentage of low, medium and high dose groups was significantly higher than that of the blank group (P<0.05). 3) At 28 days of age, the serum total protein (TP) content of medium and high dose groups was significantly higher than that of the blank group (P<0.05), and the serum albumin (ALB) content of low, medium and high dose groups was significantly higher than that of the blank group (P<0.05); at 42 days of age, the contents of TP and ALB in serum of medium and high dose groups were significantly higher than those of the blank group (P<0.05), the serum alanine aminotransferase activity of low, medium and high dose groups was significantly lower than that of the blank group (P<0.05), and the serum urea nitrogen content of medium dose group was significantly lower than that of the blank group (P<0.05). 4) The duodenal villus height of high dose group was significantly higher than that of other groups (P<0.05), the duodenal crypt depth of medium and high dose groups was significantly lower than that of the blank group (P<0.05), and the duodenal villus height/crypt depth of high dose group was significantly higher than that of other groups (P<0.05). The jejunal villus height of medium and high dose groups was significantly higher than that of the blank group (P<0.05), and the jejunal villus height/crypt depth of high dose group was significantly higher than that of the blank group (P<0.05). The ileum crypt depth of low, medium and high dose groups was significantly lower than that of the blank group (P<0.05), and the ileum villus height/crypt depth of low and high dose groups was significantly higher than that of the blank group (P<0.05). The cecum crypt depth of medium dose group was significantly lower than that of other groups (P<0.05), and the cecum villus height/crypt depth of medium dose group was significantly higher than that of other groups (P<0.05). In summary, the addition of glucose tributyrate to the diet can improve the growth performance and slaughter performance of broilers, improve intestinal mucosal morphology and promote the nutrient absorption.
LAYDEN B T,ANGUEIRA A R,BRODSKY M,et al.Short chain fatty acids and their receptors:new metabolic targets[J].Translational Research,2013,161(3):131-140.
SORET R,CHEVALIER J,DE COPPET P,et al.Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats[J].Gastroenterology,2010,138(5):1772-1782.
[11]
DHANALAKSHMI S,DEVI R S,SRIKUMAR R,et al.Protective effect of Triphala on cold stress-induced behavioral and biochemical abnormalities in rats[J].Yakugaku Zasshi,2007,127(11):1863-1867.
CRESCI G,NAGY L E,GANAPATHY V.Lactobacillus GG and tributyrin supplementation reduce antibiotic-induced intestinal injury[J].Journal of Parenteral and Enteral Nutrition,2013,37(6):763-774.
