Advances in Absorption and Metabolism of Folate and Its Mechanism in Layers
SUN Dandan1,2, ZHANG Junmin1,2, ZHAO Qingyu1,2, QIN Yuchang1
1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
2. Scientific Observing and Experiment Station of Animal Genetic Resources and Nutrition in North China of Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China
Abstract：Insufficient folate intake is a global problem, and low levels of folate in the human body increase the risk of anemia, malformation, cardiovascular and cerebrovascular diseases, cancer and cognitive impairment. However, excessive intake of oxidized folic acid may cause a potential risk. The oxidized folic acid is converted into a natural form of 5-methyltetrahydrofolate by the layers, so that the human can solve the problem of insufficient folic acid intake while ingesting food. This paper reviewed the folic acid enrichment rule in eggs and its absorption and metabolism in the intestine, liver, ovary and kidney, and the metabolic regulation mechanism of folate in layers was explained. The purpose of this paper was to provide theoretical basis for further research of folic acid in layers.
孙丹丹, 张军民, 赵青余, 秦玉昌. 叶酸在蛋鸡体内吸收代谢及其机制研究进展[J]. 动物营养学报, 2020, 32(6): 2467-2475.
SUN Dandan, ZHANG Junmin, ZHAO Qingyu, QIN Yuchang. Advances in Absorption and Metabolism of Folate and Its Mechanism in Layers. Chinese Journal of Animal Nutrition, 2020, 32(6): 2467-2475.
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