朊蛋白（prion proteins, PrP）是近年来确认的引起人畜共患病的新型蛋白质类传染源，其在乳及乳制品中的存在直接关系到乳产品安全和人类健康。本文对朊蛋白生物学特点、乳及乳制品中朊蛋白的来源和含量以及安全性进行了综述，以便为乳制品加工和安全评价提供参考。

Prion proteins were regarded as newly sources of infection that resulted in zoonosis. The safety of prion proteins in milk and milk products has a directly relationship with milk safety and human health. In this paper, the biological character, source and content of prion proteins in milk and milk products and their safety were reviewed. The aim of this paper is to provide reference to the milk processing and safety evaluation.［Chinese Journal of Animal Nutrition, 2010，22（5）:1177-1180］