本试验旨在研究共轭亚油酸（CLA）对大黄鱼（Pseudosciaena crocea, R）生长和免疫指标的影响。选用初体重为（146.25±10.62） g的大黄鱼1 600尾，随机分为4组，每组2个重复，每个重复200尾，分别饲喂在基础日粮中添加了0%、1%、2%和4%共轭亚油酸的试验日粮，试验共进行10周。结果表明，与未添加共轭亚油酸组相比，各共轭亚油酸添加组的饵料系数（FE）、特定生长率（SGR）、肥满度（CF）、肝体比（HSI）和脏体比（VSI）未产生显著影响（P>0.05）。添加共轭亚油酸能够显著提高血清中溶菌酶、免疫球蛋白M（IgM）、血清超氧化物歧化酶（SOD）和肝脏SOD活性（P<0.05），并且随共轭亚油酸含量的升高，活性也升高。血清补体（C3、C4）活性2%和4%共轭亚油酸组显著提高（P<0.05），且以2%组活性最高，并显著高于1%和4%组（P<0.05）；肌肉SOD 2%和4%共轭亚油酸组显著提高（P<0.05），且以4%组活性最高，但与1%和2%组差异不显著（P>0.05）。由此得出，日粮中添加1%~4%CLA不能提高大黄鱼的生长性能，但可显著提高大黄鱼的机体免疫能力。

To investigate the effects of conjugated linoleic acid (CLA) on growth and immune indices of large yellow croaker (Pseudosciaena crocea, R), one thousand and six hundred fish with an average initial body weight of (146.25±10.62) g were randomly divided into 4 groups with 2 replicates each and 200 fish in each replicate. Four groups were fed basal diets with 0%, 1%, 2% and 4% CLA, respectively. The experiment lasted for 10 weeks. The results showed that, compared with the control group, the feed efficiency (FE), specific growth rate (SGR), condition factor (CF), hepatosomatic index (HSI) and viscerosomatic index (VSI) were not significantly affected by adding 1%～4% CLA (P>0.05); the activities of lysozyme, IgM and superoxide dismutase (SOD) in serum and SOD in liver were significantly improved by adding 1%～4% CLA (P<0.05), and the activities were increased with the CLA level increasing; the activities of serum complement components (C3, C4) in 2% and 4% groups were significantly increased (P<0.05), the highest activities of serum complement components (C3, C4) were found in 2% group which were significantly higher than that in 1% and 4% groups; the activities of liver SOD in 2% and 4% groups were significantly increased (P<0.05), the highest activities of liver SOD were found in 4% group. No significant difference was found among 1%, 2% and 4% groups (P>0.05). It was concluded that supplementation of 1%～4% CLA in the diet of large yellow croaker could effectively increase the activity of immune indices though it had no effect on growth performance.