The experiment was conducted to compare the effects of solid-state fermented (SSF) compound protein and non solid state fermented (NSSF) compound protein on digestive physiology and nutrient apparent digestibility in growing pigs. Eighteen PIC growing barrows with average body weight of (27.7±3.3) kg were randomly divided into 3 treatments of 6 replicates per treatment and 1 pig per replicate. Three treatments were consisted of basal diet group, NSSF group and SSF group. Pigs were fed with corn-soybean meal as basal diet. Experimental diets were the basal diet replaced 30% crude protein with 12.04% SSF compound protein and 13.34% NSSF compound protein, respectively. Chromium oxide was added into the diets as an indicator, the trial lasted for 8 d. The feces were collected during the experimental period, and five barrows per treatment were humanely killed at the end of the experiment. The chyme of stomach, duodenum, jejunum, ileum and caecum were collected to study the effects of different treatments on digestive physiology and nutrient apparent digestibility in growing pigs. The results were showed as follows: 1) pH of stomach chyme of SSF group was significantly lower than that of NSSF group and basal diet group (P<0.05 or P<0.01), and pH of ileum chyme of SSF group also significantly lower than that of NSSF group (P<0.05); 2) relative viscosity of stomach chyme of SSF group and NSSF group were significantly higher than that of basal diet group (P<0.05 or P<0.01); 3) pepsin activity in stomach, trypsin, amylopsin and pancrelipase activity in small intestine of SSF group and basal diet group did not significantly differ (P>0.05), while the two groups were significantly higher than that of NSSF group (P<0.05 or P<0.01); 4) acetic acid, total volatile fatty acids and ammonia contents in caecum of SSF group were significantly lower than that of basal diet group and NSSF group (P<0.05 or P<0.01), total volatile basic nitrogen content in the caecum of SSF group and basal diet group were significantly lower than that of NSSF group (P<0.05); 5) total intestinal tract apparent digestibility of CP and ADF, and apparent ileal digestibility of most amino acids of SSF group and basal diet group were significantly higher than that of NSSF group (P<0.05 or P<0.01). The results indicate that compare with 13.34% NSSF compound protein, 12.04% SSF compound protein in growing pig diet can decrease the pH of chyme in stomach and ileum, decrease the microorganism metabolites in the caecum, and improve the digestive enzyme activity of chyme in small intestine and nutrient apparent digestibility.［Chinese Journal of Animal Nutrition，2011，23（1）：86-93］