Molecular Nutrition

Silica Gel Controlled-Release Butyrate Affects Growth Performance and Intestinal Mucosal Barrier in Weaned Piglets

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  • Institute of Feed Science, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China

Received date: 2011-07-07

  Online published: 2011-12-14

Abstract

This experiment was conducted to study the effects of silica gel controlled-release butyrate (SG-B) on growth performance and intestinal mucosal barrier in weaned piglets. SG-B was synthesized and characterized. A total of 54 piglets (Duroc × Landrace × Yorkshire) with an average body weight of (5.8±0.2) kg were weaned at 21 d, and randomly allocated into 3 groups: control group (basal diet), sodium butyrate group (basal diet + 0.10% sodium butyrate), and SG-B group (basal diet + 0.19% SG-B), with 3 replicates in each group and 6 piglets per replicate. The experiment lasted for 10 days. The results showed as follows: 1) the butyrate content was 41.1% in the SG-B. 2) The average daily gain of the SG-B group was significantly higher than that of the control group (P<0.05), and the feed/gain and diarrhea rate of the SG-B group were significantly lower than those of the control group (P<0.05). 3) D-lactate concentration and diamine oxidase activity in plasma of the SG-B group were significantly lower than those of the control group (P<0.05), and there was no significant difference between the SG-B group and sodium butyrate group (P>0.05). 4) The villus height and villus height/crypt depth in the duodenum, jejunum, and ileum of the SG-B group were significantly higher than those of the control group (P<0.05), and the crypt depth in the duodenum and ileum was significantly lower than that of the control group (P<0.05). The results indicate that supplementation with 0.19% SG-B can improve growth performance, decrease diarrhea rate and protect intestinal mucosal barrier.

Cite this article

HU Caihong, ZHU Kang, QIAN Zhongcang, LUAN Zhaoshuang, LI Weifen . Silica Gel Controlled-Release Butyrate Affects Growth Performance and Intestinal Mucosal Barrier in Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2011 , 23(12) : 2170 -2176 . DOI: 10.3969/j.issn.1006-267x.2011.12.019

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