Effects of Chitosan on Immune Function of Aquatic Animals and Its Possible Regulation Mechanism

XIAO Weiwei1,2，FENG Lin1,2，LIU Yang1,2，JIANG Jun1,2，LI Shuhong1,2，ZHOU Xiaoqiu1,2*

doi:10.3969/j.issn.1006-267x.2010.03.005

Chinese Journal of Animal Nutrition >

2010 , Vol. 22 >Issue 03: 544 - 550

DOI: https://doi.org/10.3969/j.issn.1006-267x.2010.03.005

Molecular Nutrition

Effects of Chitosan on Immune Function of Aquatic Animals and Its Possible Regulation Mechanism

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(1. Animal Nutrition Institute, Sichuan Agricultural University, Ya’an 625014, China; 2. Key Laboratory for Animal
Disease-resistance Nutrition of China Minstry of Education, Ya’an 625014, China)

Online published: 2010-03-20

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Abstract

It was found that chitosan could improve the non-specific immune function of aquatic animals through enhancing the activities of antimicrophyte enzymes and the phagocytosis ability of phagocyte. Chitosan could also promote the production of antibody, thus improved the specific immune function of aquatic animals. However, there were few studies on its regulation mechanism in the aquatic animals. The studies in the terrestrial animals field indicated that the improvement of immune function by adding chitosan might result mainly from regulating the NO and PGE2 production in immune cells. ［Chinese Journal of Animal Nutrition, 2010，22（3）:544-550］

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XIAO Weiwei1,2，FENG Lin1,2，LIU Yang1,2，JIANG Jun1,2，LI Shuhong1,2，ZHOU Xiaoqiu1,2* . Effects of Chitosan on Immune Function of Aquatic Animals and Its Possible Regulation Mechanism[J]. Chinese Journal of Animal Nutrition, 2010 , 22(03) : 544 -550 . DOI: 10.3969/j.issn.1006-267x.2010.03.005

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