Effects of Dietary Nucleotides on Growth Performance, Body Composition and Serum Biochemical Parameters of Grass Carp (Ctenopharyngodon idella)
WANG Hongquan1,2, LI Rui1, JIN Botao3, ZHAO Yurong1
1. College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China;
2. Hunan Collaborative Innovation Center for Efficient and Healthy Production of Aquatic Products, Changde 415000, China;
3. Changde Dabei Agricultural Feed Company Limited, Changde 415000, China
Abstract：This experiment was conducted to investigate the effects of dietary nucleotides on growth performance, body composition and serum biochemical parameters of grass carp (Ctenopharyngodon idellus). A total of 720 healthy grass carp with initial body weight of (10.79±0.25) g were randomly divided into 6 groups with 4 replicates in each group and 30 fish in each replicate. Fish in each group were the basal diet supplemented with 0 (control), 0.015%, 0.030%, 0.060%, 0.120% and 0.180% nucleotides, respectively. The experiment lasted for 60 days. The results showed as follows:1) dietary nucleotides had no significant effects on weight gain rate, specific growth rate, feed conversion ratio and body composition of grass carp (P>0.05). 2) Compared with the control group, dietary nucleotides significantly decreased the serum malondialdehyde (MDA) content of grass carp (P<0.05), and significantly increased the total superoxide dismutase (T-SOD), catalase (CAT), lysozyme (LSZ) activities and complement 3 (C3) content in serum of grass carp (P<0.05). These results indicate that dietary nucleotides have no significant effects on growth performance and body composition of grass carp, and can improve the antioxidant capacity and non-specific immunity capacity of grass carp. According to the regression analysis, when dietary nucleotides supplemental level is 0.082% to 0.150%, the antioxidant capacity and non-specific immunity capacity of grass carp are better.
王红权, 李瑞, 金柏涛, 赵玉蓉. 饲料中添加核苷酸对草鱼生长性能、体成分及血清生化指标的影响[J]. 动物营养学报, 2019, 31(6): 2745-2751.
WANG Hongquan, LI Rui, JIN Botao, ZHAO Yurong. Effects of Dietary Nucleotides on Growth Performance, Body Composition and Serum Biochemical Parameters of Grass Carp (Ctenopharyngodon idella). Chinese Journal of Animal Nutrition, 2019, 31(6): 2745-2751.
MURTHY H S, LI P, LAWRENCE A L, et al.Dietary β-glucan and nucleotide effects on growth, survival and immune responses of Pacific white shrimp, Litopenaeus vannamei[J].Journal of Applied Aquaculture, 2009, 21(3):160-168.
[11]
MOHEBBI A, NEMATOLLAHI A, GHOLAMHOSEINI A, et al.Effects of dietary nucleotides on the antioxidant status and serum lipids of rainbow trout (Oncorhynchus mykiss)[J].Aquaculture Nutrition, 2013, (19):506-514.
孟玉琼.饲料中添加ROVIMAX NX对大菱鲆(Scophthatmus maximus L.)生长性能、免疫和肠道形态学的影响[D].硕士学位论文.青岛:中国海洋大学, 2013.
[9]
LIN Y H, WANG H, SHIAU S Y.Dietary nucleotide supplementation enhances growth and immune responses of grouper, Epinephelus malabaricus[J].Aquaculture Nutrition, 2009, 15(2):117-122.
TAHMASEBI-KOHYANI A, KEYVANSHOKOOH S, NEMATOLL A, et al.Dietary administration of nucleotides to enhance growth, humoral immune responses, and disease resistance of the rainbow trout (Oncorhynchus mykiss) fingerlings[J].Fish and Shellfish Immunology, 2011, 30(1):189-193.
LI P, LEWIS D H, GATLIN D M Ⅲ, et al.Dietary oligonucleotide from yeast RNA influences immune responses and resistance of hybrid striped bass (Morone chrysops×Morone saxatilis) to Streptococcus iniae infection[J].Fish and Shellfish Immunology, 2004, 16(5):561-69.
[19]
OLIVA-TELES A, GONCALVES P.Partial replacement of fishmeal by brewers yeast (Saccaromyces cerevisae) in diets for sea bass (Dicentrarchus labrax) juveniles[J].Aquaculture, 2001, 202(3):269-278.
[23]
ABTAHI B, YOUSEFI M, KENARI A A.Influence of dietary nucleotides supplementation on growth, body composition and fatty acid profile of Beluga sturgeon juveniles (Huso huso)[J].Aquaculture Research, 2013, 44(2):254-260.
