Effects of Serotonin on Performance and Plasma and Milk Calcium Transport Related Biochemical Index of Perinatal Ewes
SANG Dan1,2, NAMIRGA1,2, SUN Haizhou2, JIN Lu2, ZHANG Chongzhi2, LI Shengli2, WANG Shuangsuo3, LIU Yongjun3, AO Changjin1
1. College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China;
2. Animal Nutrition and Feed Research Institution of Inner Mongolia Academy of Agriculture and Animal Husbandry Academy, Hohhot 010031, China;
3. Urat Front Banner Livestock Improvement Station, Bayannur 014400, China
Abstract：This experiment was conducted to investigate effects of serotonin (5-HT) on performance and plasma and milk calcium transport related biochemical index of perinatal ewes. Thirty Bamei ewes with similar body weight were randomly allotted 3 groups, which were control group, 5-hydroxy-tryptophan (5-HTP) group (perfused 5-HTP) and tryptophan (Trp) group (perfused Trp), respectively, each group contained 10 ewes. Ewes jugular vein perfusion was conducted from prenatal day 7 to postpartum day 0, the perfusion dose of 5-HTP and Trp was 0.178 mg/kg BW, and the concentration was 0.1 mg/mL; the control group was perfused with the same dose of saline. The experiment lasted form prenatal day 7 to postpartum day 30. The results showed as follows:1) there was no significant difference in body weight of ewes among all groups (P>0.05). On postpartum day 5, 9 and 15, the milk yield of ewes in Trp group was lower than that in the control group (P>0.05); on postpartum day 9 and 15, the milk yield of ewes in 5-HTP group was higher than that in the control group (P>0.05). On postpartum day 16 to 30, the average daily gain of lambs in 5-HTP group was significantly higher than that in the control group (P<0.05). 2) On postpartum day 15, the plasma and milk calcium concentration in Trp group was significantly higher than that in the control group (P<0.05); on postpartum day 3, 6 and 15, the plasma and milk calcium concentration in 5-HTP group was significantly higher than that in the control group (P<0.05). On postpartum day 6, the plasma 5-HT concentration in Trp group was significantly higher than that in the control group (P<0.05); on postpartum day 30, the milk 5-HT concentration in Trp group was significantly higher than that in the control group (P<0.05); on postpartum day 6, 9 and 30, the plasma and milk 5-HT concentration in 5-HTP group was significantly higher than that in the control group (P<0.05). On postpartum day 3, 6 and 15, the plasma parathyroid hormone-related protein (PTHrP) concentration in Trp group and 5-HTP group was significantly higher than that in the control group (P<0.05). In conclusion, perfuse 5-HTP can promote the lactation of ewes, improve the average daily gain of lambs; perfuse 5-HTP and Trp can increase the concentration of calcium and 5-HT in plasma and milk and PTHrP in plasma.
桑丹, 娜美日嘎, 孙海洲, 金鹿, 张崇志, 李胜利, 王双锁, 刘拥军, 敖长金. 5-羟色胺对围产期母羊生产性能及血浆和乳中钙转运相关生化指标的影响[J]. 动物营养学报, 2019, 31(7): 3174-3180.
SANG Dan, NAMIRGA, SUN Haizhou, JIN Lu, ZHANG Chongzhi, LI Shengli, WANG Shuangsuo, LIU Yongjun, AO Changjin. Effects of Serotonin on Performance and Plasma and Milk Calcium Transport Related Biochemical Index of Perinatal Ewes. Chinese Journal of Animal Nutrition, 2019, 31(7): 3174-3180.
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