Abstract：The purpose of this experiment was to study the effects of zinc lactate on growth performance, intestinal development and serum biochemical indexes of weaned rabbits. In the experiment, 420 weaned New Zealand rabbits at 28 days of age were randomly divided into 5 group: control group (fed a basal diet supplemented with 0 mg/kg zinc sulfate), zinc sulfate group (fed the basal diet supplemented with 80 mg/kg zinc sulfate) and three zinc lactate groups (fed the basal diet supplemented with 20, 40 and 80 mg/kg zinc lactate, respectively), and each group had 14 replicates with 6 rabbits (half male and half female) per replicate. The pre-experimental period lasted for 7 days,and the experimental period lasted for 42 days.The results showed as follows: 1) compared with control group, the diet supplemented with 40 and 80 mg/kg zinc lactate significantly increased the final body weight and average daily gain of weaned rabbits (P<0.05), decreased the feed to weight ratio, diarrhea rate and mortality (P<0.05), but had no significant effect on the average daily intake (P>0.05); the final body weight, average daily gain and feed to weight ratio of 40 mg/kg zinc lactate group was not different from zinc sulfate group (P>0.05), but diarrhea rate and mortality were lower. 2) Compared with control group, adding 40 and 80 mg/kg zinc lactate to the diet could significantly increase the villus height and villus height/crypt depth of small intestine (P<0.05), and significantly decrease the depth of duodenal crypt (P<0.05); the height of duodenal villus in 80 mg/kg zinc lactate group was significantly higher than that in the same level zinc sulfate group (P<0.05). 3) Compared with control group, adding 40 and 80 mg/kg zinc lactate to the diet could significantly improve the serum antioxidant enzyme activity, growth hormone and insulin-like growth factor-Ⅰ contents of weaned rabbits (P<0.05); the serum biochemical indexes in 40 mg/kg zinc lactate group were not different from those in zinc sulfate group (P>0.05), and 80 mg/kg zinc lactate group was superior to the same level zinc sulfate group in improving the serum copper zinc superoxide dismutase activity and growth hormone content of weaned rabbits. Therefore, zinc lactate added to the diet can promote the growth of meat rabbits, reduce the diarrhea rate and mortality rate, improve serum biochemical indexes and intestinal development; the effects of zinc lactate added is significantly better than that of zinc sulfate at the same level, and the appropriate amounts of zinc lactate in diet is 40 mg/kg in rabbit production.
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