研究简报

三聚氰酸和三聚氰胺对肉鸡生长性能的影响及其组织残留的研究

展开
  • 四川农业大学动物营养研究所,教育部抗病营养重点实验室,雅安625014
王亮(1985—),男,山东青岛人,硕士研究生,研究方向为家禽营养。E-mail: panda3785646@163.com

网络出版日期: 2011-06-17

基金资助

农业部饲料中三聚氰胺限量制定专项和四川农业大学双支计划团队资助

Cyanuric Acid and Melamine: Effects on Growth Performance and Their Residues in Tissues of Broilers

Expand
  • Institute of Animal Nutrition, Key Laboratory for Animal Disease-resistance Nutrition of China Ministry of Education, Sichuan Agricultural University, Ya’an 625014, China

Online published: 2011-06-17

摘要

本试验旨在探讨饲粮中添加不同水平的三聚氰酸(cyanuric acid,CYA)和/或三聚氰胺(melamine,MEL)对肉鸡生长性能的影响及其在血浆、组织中的残留。试验采用2×5两因子设计,1 200只1日龄科宝 500肉鸡公雏随机分为10个处理,每个处理6个重复,每个重复20只鸡。CYA设5个水平:0、10、20、33.3和50 mg/kg,MEL设2个水平:0和100 mg/kg。试验期42 d。结果表明,CYA对肉鸡体重、体增重、平均日采食量及料重比无显著影响(P>0.05),单独添加10~50 mg/kg CYA对肉鸡21 d体重、1~21 d体增重和平均日采食量有不利影响(P>0.05)。CYA和/或MEL未影响肉鸡对饲粮粗蛋白质、钙和磷的利用率(P>0.05),但50 mg/kg CYA显著降低饲粮总能利用率(P<0.05)。饲粮添加CYA和/或MEL可在肉鸡血浆、肾脏检出CYA残留;所有处理肉鸡肌肉、肝脏、肾脏中均检出MEL残留,二者联合添加增加了肉鸡组织中MEL的残留量。由此可知,饲粮单独添加CYA 10~50 mg/kg对幼龄肉鸡生长性能有不利影响,50 mg/kg CYA显著降低饲粮总能利用率;饲粮添加CYA和/或MEL可在肉鸡组织中检出CYA和MEL,联合添加增加组织中MEL残留量,二者比例影响MEL残留量。

本文引用格式

王亮,丁雪梅,张克英,白世平,吴彩梅 . 三聚氰酸和三聚氰胺对肉鸡生长性能的影响及其组织残留的研究[J]. 动物营养学报, 2011 , 23(06) : 1019 -1026 . DOI: 10.3969/j.issn.1006-267x.2011.06.020

Abstract

The purpose of this study was to evaluate the effects of cyanuric acid (CYA) and a combination of melamine (MEL) and CYA on growth performance and residues in plasma and tissues in broilers. A total of 1 200 COBB 500 male broilers were randomly allocated into 10 treatments by a 2×5 factorial design in a 42-day experiment. The dietary treatments were as follows: treatments 1 to 5 were basal diets with supplementation of CYA at 0, 10, 20, 33.3 and 50 mg/kg, respectively; treatments 6 to 10 were basal diets with CYA regimens similar to treatments 1 to 5 but with supplementation of MEL at 100 mg/kg in the same time. There were 6 replicates (pens) per treatment with 20 chicks per pen. The results showed that no significant differences were found on body weight, body weight gain, average daily feed intake, feed to gain ratio, and digestibility of crude protein, Ca and P (P>0.05), but CYA supplementation had adverse effects on body weight of d 21, body weight gain of d 1 to 21, and average daily feed intake (P>0.05). Apparent availability of gross energy (GE) was lowered when birds were fed CYA at 50 mg/kg (P<0.05). The residues of CYA in plasma and kidney could be detected at the highest levels when CYA was supplemented alone at 33.3 or 50 mg/kg. When CYA was supplemented alone, the residues of MEL in breast muscle, liver, and kidney could be detected, while MEL in liver and kidney could be increased significantly with the supplementation of CYA and MEL together. These results indicate that supplementation of CYA at 10 to 50 mg/kg can decrease the growth performance of broilers, and the apparent availability of GE can be reduced by CYA at 50 mg/kg significantly. Residues of CYA and MEL in broiler tissues can be detected with dietary CYA and/or MEL, and they together can increase MEL residue. Besides, their proportion affects the level of MEL residue.[Chinese Journal of Animal Nutrition, 2011, 23(6):1019 -1026]

参考文献

[1]REIMSHUESSEL R, HATTAN D G, GU Y. Background paper on toxicology of melamine and its analogues[R]. Ottawa:WHO & FAO, 2008.

[2]LIM L O, SCHERER S J, SHULER K D, et al. Disposition of cyromazine in plants under environmental conditions[J]. Journal of Agricultural and Food Chemistry, 1990, 38: 860-864.

[3]胡虎,盛宏强,马晓琼,等.三聚氰胺及其同系物三聚氰酸的生物学效应和毒理学研究进展[J].浙江大学学报:医学版,2008,37(6):544-550.

[4]BROWN C A, JEONG K S, POPPENGA R H, et al. Outbreaks of renal failure associated with melamine and cyanuric acid in dogs and cats in 2004 and 2007[J]. Journal of Veterinary Diagnostic Investigation, 2007, 19:525-531.

[5]李倜,丁雪梅,张克英,等.饲粮中添加三聚氰胺对肉鸡生长性能和健康的影响[J].动物营养学报,2010,22(6):694-1702.

[6]丁雪梅,张克英,王亮.三聚氰胺对肉鸡毒性作用分析[J].动物营养学报,2011,23(1):122-129.

[7]QIU J, ZHANG Y, YU H X, et al. An optimized method for simultaneous determination of melamine and cyanuric acid in animal tissues by liquid chromatography-triple quadrupole mass spectrometry[J]. Der Pharma Chemica, 2009, 1(2):269-277.

[8]PUSCHNER B, POPPENGA R H, LOWENSTINE L J, et al. Assessment of melamine and cyanuric acid toxicity in cats[J]. Journal of Veterinary Diagnostic Investigation, 2007, 19:616-624.

[9]DOBSON R L M, MOTLAGH S, QUIJANO M, et al. Identification and characterization of toxicity of contaminants in pet food leading to an outbreak of renal toxicity in cats and dogs[J]. Toxicilogical Sciences, 2008, 106(1):251-262.

[10]GAO C Q, WU S G, YUE H Y, et al. Toxicity of dietary melamine to laying ducks: biochemical and histopathological changes and residue in eggs[J]. Journal of Agricultural and Food Chemistry, 2010, 58, 5199-5205.

[11]LV M B, YAN L, GUO J Y, et al. Melamine residues in tissues of broilers fed diets containing graded levels of melamine[J]. Poultry Science, 2009, 88:2167-2170.

[12]XU W, DONG M D, GERSEN H, et al. Cyanuric acid and melamineon Au(111): structure and energetics of hydrogen-bonded networks[J]. Small, 2007(3):854-858.

[13]BAI X, BAI F, ZHANG K Y, et al. Tissue deposition and residue depletion in laying hens exposed to melamine-contaminated diets[J]. Journal of Agricultural and Food Chemistry, 2010, 58:5414-5420.

[14]武书庚,高春起,岳洪源,等.三聚氰胺在鸭蛋中的沉积和消除规律的研究[J].动物营养学报,2010,22(2):416-423.

[15]LV X W, WANG J, WU L, et al. Tissue deposition and residue depletion in lambs exposed to melamine and cyanuric acid-vontaminated diets[J]. Journal of Agricultural and Food Chemistry. 2010, 58:943-948.

[16]REIMSHUESSEL R, GIESEKER C M, MILLER R A, et al. Evaluation of the renal effects of experimental feeding of melamine and cyanuric acid to fish and pigs[J]. American Journal of Veterinary Research. 2008, 69:1217-1228.

[17]SEFFERNICK J L, SOUZA M L, SADOWSKY M J, et al. Melamine deaminase and atrazine chlorohydrolase: 98 percent identical but functionally different[J]. Journal of Bacteriology, 2001, 183(8):2405-2410.
文章导航

/