[1] SARA A,SALLY R,ANDREW W,et al.Egr-1 binds the GnRH promoter to mediate the increase in gene expression by insulin[J].Molecular and Cellular Endocrinology,2007,270(1/2):64-72.
[2] LIU F,USUI I,EVANS L G,et al.Involvement of both Gq/11 and Gs proteins in gonadotropin-releasing hormone receptor-mediated signaling in LβT2 cells[J].Journal of Biological Chemistry,2002,277(35):32099-32108.
[3] NAVRATIL A M,SONG H,HERNANDEZ J B,et al.Insulin augments gonadotropin-releasing hormone induction of translation in LβT2 cells[J].Molecular and Cellular Endocrinology,2009,311(1/2):47-54.
[4] HILL J W,ELMQUIST J K,ELIAS C F.Hypothalamic pathways linking energy balance and reproduction[J].American Journal of Physiol Endocrinology and Metabolism,2008,294:E827-E832.
[5] XU J,KIRIGITI M A,GROVE K L,et al.Regulation of food intake and gonadotropin-releasing hormone/luteinizing hormone during lactation:role of insulin and leptin[J].Endocrinology,2009,150:4231-4240.
[6] 陈永辉,肖勇,伍小松,等.饲粮能量对后备母猪初情期启动的调控作用[J].动物营养学报,2011,23(6):914-918.
[7] 苏娟.Orexin在体内外对母猪下丘脑-垂体-性腺轴作用机理的研究 .博士学位论文.南京:南京农业大学,2008.
[8] WOODS S C,LOTTER E C,MCKAY L D,et al.Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons[J].Nature,1979,282:503-505.
[9] BRUNING J C,GAUTAM D,BURKS D J,et al.Role of brain insulin receptor in control of body weight and reproduction[J].Science,2000,289:2122-2125.
[10] KHACHIGIAN L M.Early growth response-1 in cardiovascular pathobiology[J].Circulation Research,2006,98(2):186-191.
[11] 刘炘,刘丽莎,邱文,等.大鼠野生型
Egr-1基因及
Egr-1 shRNA真核表达质粒的构建及鉴定[J].南京医科大学学报:自然科学版,2010,30(5):607-611.
[12] DYSON O F,WALKER L R,COOK P P,et al.Resveratrol inhibits KSHV reactivation by lowering the levels of cellular EGR-1[J].PLoS One,2012,7(3):e33364.
[13] FU M,ZHANG J,LIN Y,et al.Early growth response factor l is a critical transcriptional mediator of peroxisome proliferator-activated receptor-1 gene expression in human aortic smooth muscle cells[J].Journal of Biological Chemistry,2002,277(30):26808-26814.
[14] GARNETT K E,CHAPMAN P,CHAMBERS J A,et al.Differential gene expression between Zucker fatty rats and Zucker diabetic fatty rats:a potential role for the immediate-early gene
Egr-1 in regulation of beta cell proliferation[J].Journal of Molecular Endocrinology,2005,35:13-25.
[15] GIVENS M L,RAVE-HAREL N,GOONEWARDENA V D,et al.Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families[J].Journal of Biological Chemistry,2005,280:19156-65.
[16] KIM H H,WOLFE A,COHEN R N,et al.
In vivo identification of a 107-base pair promoter element mediating neuron-specific expression of mouse gonadotropin-releasing hormone[J].Molecular Endocrinology,2007,21:457-72.
[17] KIM H H,DIVALL S A,DENEAU R M,et al.Insulin regulation of
GnRH gene expression through MAP kinase signaling pathways[J].Molecular and Cellular Endocrinology,2005,242:42-49.
[18] SALVI R,CASTILLO E,VOIROL M J,et al.Gonadotropin-releasing hormone-expressing neurons immortalized conditionally are activated by insulin:implication of the mitogen-activated protein kinase pathway[J].Endocrinology,2006,147:816-826.
[19] KEETON A B,BORTOFF K D,BENNETT W L,et al.Insulin-regulated expression of
Egr-1 and
Krox20:dependence on ERK1/2 and interaction with p38 and PI3-kinase pathways[J].Endocrinology,2003,144:5402-5410.
[20] 李静.ERK信号转导通路在电针调节创伤应激后免疫抑制中的作用 .硕士学位论文.上海:复旦大学,2012.
[21] BLISS S P,NAVRATIL A M,XIE J J,et al.GnRH signaling,the gonadotrope and endocrine control of fertility[J].Frontiers in Neuroendocrinology,2010,31(3):322-340.
[22] 孙颖.脂筏在猪繁殖与呼吸综合征病毒感染中作用的初步探讨 .硕士学位论文.武汉:华中农业大学,2009.
[23] BLISS S P,NAVRATIL A M,BREED M,et al.Signaling complexes associated with the type Ⅰ gonadotropin-releasing hormone (GnRH) receptor:colocalization of extracellularly regulated kinase 2 and GnRH receptor within membrane rafts[J].Molecular Endocrinology,2007,21:538-549.
[24] GETHER U,KOBILKA B K.G protein-coupled receptors.Ⅱ.Mechanism of agonist activation[J].Journal of Biological Chemistry,1998,273:17979-17982.
[25] RISPOLI L A,NETT T M.Pituitary gonadotropin-releasing hormone (GnRH) receptor:structure,distribution and regulation of expression[J].Animals Reprod Science,2005,88:57-74.
[26] LEE T,HOOFNAGLE A N,KABUYAMA Y,et al.Docking motifinteractions in MAP kinases revealed by hydrogen exchange mass spectrometry[J].Molecular Cell,2004,14:43-55.
[27] ROBERSON M S,BLISS S P,XIE J,et al.Gonadotropin-releasing hormone induction of extracellular-signal regulated kinase is blocked by inhibition of calmodulin[J].Molecular Endocrinology,2005,19:2412-2423.
[28] XIE J,ALLEN K H,MARGUET A,et al.Analysis of the calcium-dependent regulation of proline-rich tyrosine kinase 2 by gonadotropin-releasing hormone[J].Molecular Endocrinology,2008,22:2322-2335.
[29] BUGGS C,WEINBERG F,KIM E,et al.Insulin augments GnRH-stimulated
LHbeta gene expression by Egr-1[J].Molecular and Cellular Endocrinology,2006,249:99-106.
[30] ISHIKAWA Y,OTSU K,OSHIKAWA J.Caveolin,different roles for insulin signal?[J].Cell Signal,2005,17:1175-1182.
[31] BASKIN D,BREININGER J F,SCHWARTZ M W.
SOCS-3 expression in leptin-sensitive neurons of the hypothalamus of fed and fasted rats[J].Regulatory Peptides,2000,92:9-15.
[32] HILL J,LEVINE J E.Abnormal response of the neuropeptide Y-deficient mouse reproductive axis to food deprivation but not lactation[J].Endocrinology,2003,144:1780-1786.
[33] ERICKSON J C,HOLLOPETER G,PALMITER R D.Attenuation of the obesity syndrome of
ob/ob mice by the loss of neuropeptide Y[J].Science,1996,274:1704-1707.
[34] XU J,KIRIGITI M A,COWLEY M A,et al.Suppression of basal spontaneous GnRH neuronal activity during lactation:role of inhibitory effects of NPY[J].Endocrinology,2009,150:333-340.
[35] XU J,KIRIGITI M A,GROVE K L,et al.Regulation of food intake and gonadotropin-releasing hormone/luteinizing hormone during lactation:role of insulin and leptin[J].Endocrinology,2009,150:4231-4240.
[36] TITOLO D,CAI F,BELSHAM D D.Coordinate regulation of neuropeptide Y and agouti-related peptide gene expression by estrogen depends on the ratio of estrogen receptor (ER)alpha to ERbeta in clonal hypothalamic neurons[J].Molecular Endocrinology,2006,20:2080-2092.
[37] WANG J,LEIBOWITZ K L.Central insulin inhibits hypothalamic galanin and neuropeptide Y gene expression and peptide release in intact rats[J].Brain Research,1997,777:231-236.
[38] 周东胜.能量水平和来源对后备母猪血液代谢底物,激素分泌及卵泡微环境影响 .硕士学位论文.雅安:四川农业大学,2007.
[39] 周平.不同能量水平和来源对后备母猪体成分、初情日龄和发情率的影响 .硕士学位论文.雅安:四川农业大学,2007.
[40] ZHAI H L,WU H,XU H,et al.Trace glucose and lipid metabolism in high androgen and high-fat diet induced polycystic ovary syndrome rats[J].Reproductive Biology and Endocrinology,2012,10(5):2-9.
[41] KAPELANSKI W,BIEGNIEWSKA M,JANKOWIAK H,et al.Results of sow reproductive performance due to application of insulin genic diet and natural stimulation of estrus[J].Research in Pig Breeding,2008,2(2):19-21.
[42] VAN DEN BRAND H,SOEDE N M, EMP B.Supplementation of dextrose to the diet during the weaning to estrus interval affects subsequent variation in with-litter piglet brith weight[J].Animal Reproduction Science,2006,91:353-358.
京公网安备 11010802041926号