综述 Review

种蛋注射在家禽营养表观遗传学上的应用

  • 李世召 ,
  • 支丽慧 ,
  • 杨小军 ,
  • 姚军虎
展开
  • 西北农林科技大学动物科技学院,杨凌 712100

收稿日期: 2012-12-24

  网络出版日期: 2013-05-15

基金资助

国家自然基金项目(31272464、31001017);陕西省青年科技新星基金(2012KJXX-18)

Hatching Egg Injection: Application in Poultry Nutri-Epigenetics Studies

  • LI Shizhao ,
  • ZHI Lihui ,
  • YANG Xiaojun ,
  • YAO Junhu
Expand
  • College of Animal Science and Technology, Northwest A&F university, Yangling 712100, China

Received date: 2012-12-24

  Online published: 2013-05-15

摘要

胚胎期是表观基因组重编程的关键时期,易受营养物质等外界环境的影响。与哺乳动物不同,家禽的胚胎发育与母体分离,可借助种蛋注射研究营养物质对胚胎发育的影响。本文简述了种蛋注射的研究现状,结合胚胎期表观基因组的重编程机理,阐述了其在研究家禽营养表观遗传学上的重要作用。

本文引用格式

李世召 , 支丽慧 , 杨小军 , 姚军虎 . 种蛋注射在家禽营养表观遗传学上的应用[J]. 动物营养学报, 2013 , 25(6) : 1169 -1173 . DOI: 10.3969/j.issn.1006-267x.2013.06.007

Abstract

Embryo stage is one of the critical periods in reprogramming of epigenome, while it is vulnerable to the impacts of nutrients and other external environment. Different from mammal, embryonic development of poultry is separated from matrix, so the influences of nutrients to embryonic development through injecting specific nutrients into hatching egg can be assessed. This review summarized the research situation of hatching egg injection; meanwhile, combining with the mechanism of reprogramming of epigenome in embryonic period, the review elaborated its vital role in the research of poultry nutri-epigenetics.

参考文献

[1] LYKO F,FORET S,KUCHARSKI R,et al.The honey bee epigenomes:differential methylation of brain DNA in queens and workers[J].PLoS Biology,2010,8(11):e1000506.

[2] 赵冬梅,金帆,黄荷凤.表遗传修饰与配子形成和胚胎早期发育[J].国外医学:遗传学分册,2004,27(3):159-162.

[3] MAYER W,NIVELEAU A,WALTER J,et al.Demethylation of the zygotic paternal genome[J].Nature,2000,403:501-502.

[4] SANTOS F,HENDRICH B,REIK W,et al.Dynamic reprogramming of DNA methylation in the early mouse embryo[J].Developmental Biology,2002,241(1):172-182.  

[5] HYLDING S M,OSTRUP O,VEJLSTED M,et al.Changes of DNA methylation level and spatial arrangement of primordial germ cells in embryonic day 15 to embryonic day 28 pig embryos[J].Biology of Reproduction,2011,84(6):1087-1093.  

[6] 佚名.麻省理工学院Rudolf Jaenisch访谈——这就是表观遗传学[J].科学观察,2009,4(3):54-56.

[7] ROSENQUIST T H,FINNELL R H.Genes,folate and homocysteine in embryonic development[J].Proceedings of the Nutrition Society,2001,60(1):53-61.

[8] WATERLAND R A,JIRTLE R L.Transposable elements:targets for early nutritional effects on epigenetic gene regulation[J].Molecular and Cellular Biology,2003,23(15):5293-5300.  

[9] HOLLINGSWORTH J W,MARUOKA S,BOON K,et al.In utero supplementation with methyl donors enhances allergic airway disease in mice[J].The Journal of Clinical Investigation,2008,118(10):3462-3469.

[10] 宋润山,THAXTON J.实用蛋内注射技术问世[J].国外畜牧学:猪与禽,1990(1):34-35.

[11] 乐牧.种蛋内注射技术的前景[J].青海畜牧兽医杂志,1991(2):28.

[12] MARSH T E,FLUKE D K,VILLEGAS P.Efficacy of INOVOJECT egg injection system for delivering Marek's disease vaccine under hatchery conditions[J].Avian Diseases,1997,41(2):452-454.  

[13] ANNAMALAI T,SELVARAJ R.Effects of in ovo interleukin-4-plasmid injection on anticoccidia immune response in a coccidia infection model of chickens[J].Poultry Science,2012,91(6):1326-1334.  

[14] IPEK A,SAHAN U,YILMAZ B,et al.The effect of in ovo ascorbic acid and glucose injection in broiler breeder eggs on hatchability and chick weight[J].Archiv Für Geflügelkunde,2004,68(3):132-135.

[15] NOWACZEWSKI S,KONTECKA H,KRYSTIANIAK S.Effect of in ovo injection of vitamin C during incubation on hatchability of chickens and ducks[J].Folia Biologica(Krakow),2012,60(1/2):93-97.

[16] AL-DARAJI H J,AL-MASHADANI A A,AL-HAYANI W K,et al.Effect of in ovo injection with L-arginine on productive and physiological traits of Japanese quail[J].South African Journal of Animal Science,2012,42(2):139-145.

[17] KERALAPURATH M,KEIRS R,CORZO A,et al.Effects of in ovo injection of L-carnitine on subsequent broiler chick tissue nutrient profiles[J].Poultry Science,2010,89(2):335-341.  

[18] MACALINTAL L M.In ovo selenium (Se) injection of incubating chicken eggs effects on embryo viability,tissue Se concentration,lipid peroxidation,immune response and post hatch development[D].Ph.D.Thesis.Kentucky State:University of Kentucky,2012.

[19] HOSSAIN S,BARRETO S,BERTECHINI A,et al.Influence of dietary vitamin E level on egg production of broiler breeders,and on the growth and immune response of progeny in comparison with the progeny from eggs injected with vitamin E[J].Animal Feed Science and Technology,1998,73(3/4):307-317.

[20] BAKYARAJ S,BHANJA S K,MAJUMDAR S,et al.Modulation of post-hatch growth and immunity through in ovo supplemented nutrients in broiler chickens[J].Journal of the Science of Food and Agriculture,2012,92(2):313-320.  

[21] OHTA Y,KIDD M T.Optimum site for in ovo amino acid injection in broiler breeder eggs[J].Poultry Science,2001,80(10):1425-1429.

[22] OHTA Y,TSUSHIMA N,KOIDE K,et al.Effect of amino acid injection in broiler breeder eggs on embryonic growth and hatchability of chicks[J].Poultry Science,1999,78(11):1493-1498.

[23] 孙研研,郑江霞,徐桂云,等.外源基因导入鸡胚的两种显微注射方法的比较[J].农业生物技术学报,2010,18(5):938-943.
文章导航

/