综述 Review

差异蛋白质组学在乳蛋白研究中的应用进展

  • 陈静廷 ,
  • 马露 ,
  • 杨晋辉 ,
  • 张娟霞 ,
  • 李发第 ,
  • 卜登攀
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  • 1. 中国农业科学院北京畜牧兽医研究所,动物营养学国家重点实验室,北京 100193;
    2. 甘肃农业大学动物科学技术学院,兰州 730070

收稿日期: 2013-02-01

  网络出版日期: 2013-07-15

基金资助

"十二五"国家科技支撑计划(2012BAD12B02-05);动物营养学国家重点实验室自主研究课题(2004DA125184G1103)

Application of Differential Proteomics in Milk Protein Studies

  • CHEN Jingting ,
  • MA Lu ,
  • YANG Jinhui ,
  • ZHANG Juanxia ,
  • LI Fadi ,
  • BU Dengpan
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  • 1. State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China

Received date: 2013-02-01

  Online published: 2013-07-15

摘要

蛋白质组学是后基因时代的重要研究方向之一,有助于了解乳蛋白的组成、表达水平及修饰状态等,在乳蛋白的研究中具有广泛的应用前景.而差异蛋白质组学是蛋白质组学研究的主要内容之一,可反映蛋白质的动态本质.本文主要就差异蛋白质组学在乳蛋白含量及组分、疾病生物学标记的鉴定及乳蛋白热处理的变化等方面的研究进行综述.

本文引用格式

陈静廷 , 马露 , 杨晋辉 , 张娟霞 , 李发第 , 卜登攀 . 差异蛋白质组学在乳蛋白研究中的应用进展[J]. 动物营养学报, 2013 , 25(8) : 1683 -1688 . DOI: 10.3969/j.issn.1006-267x.2013.08.004

Abstract

Proteomics, as one of important research directions after genomics, had a wide range of application for studying the composition, expression level and modification status of milk proteins. Differential proteomics as one of the main contents of proteomics could reflect the dynamic nature of proteins. This article mainly reviewed the researches of differential proteomics in milk protein content and composition, disease biomarkers identification and the influence of thermal treatment on milk proteins, etc.

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