综述 Review

磷壁酸在细菌黏附、定植及免疫调节过程中的作用

  • 王进波 ,
  • 倪江 ,
  • 高权新 ,
  • 齐莉莉
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  • 1. 浙江大学宁波理工学院, 宁波 315100;
    2. 中国水产科学院东海水产研究所, 农业部东海与远洋渔业资源开发利用重点实验室, 上海 200090

收稿日期: 2013-03-22

  网络出版日期: 2013-08-18

基金资助

国家自然科学基金项目(30901039、31272461);宁波市自然科学基金项目(2012A610146)

Teichoic Acid:Roles in Adhesion, Colonization and Immune Regulation of Bacteria

  • WANG Jinbo ,
  • NI Jiang ,
  • GAO Quanxin ,
  • QI Lili
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  • 1. Ningbo Institue of Technology, Zhejiang University, Ningbo 315100, China;
    2. Key Laboratory of East China Sea and Oceanic Fishery Resources Exploitation, Ministry of Agriculture of China, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China

Received date: 2013-03-22

  Online published: 2013-08-18

摘要

磷壁酸是革兰氏阳性菌细胞壁的主要成分,在细菌自我保护、离子平衡、细胞分裂及其与宿主细胞互作等过程中发挥着重要生理作用。本文综述了磷壁酸在革兰氏阳性菌黏附、定植及免疫调节过程中的作用,阐述了磷壁酸识别的细胞膜受体蛋白,旨在为深入解析细菌在肠黏膜细胞膜上的黏附定植机制提供新线索。

本文引用格式

王进波 , 倪江 , 高权新 , 齐莉莉 . 磷壁酸在细菌黏附、定植及免疫调节过程中的作用[J]. 动物营养学报, 2013 , 25(9) : 1916 -1920 . DOI: 10.3969/j.issn.1006-267x.2013.09.002

Abstract

Teichoic acid is one of the major components of cell wall of Gram-positive bacteria, which plays important physiological roles in the self-protection, ionic equilibrium, cell division and the interaction with host cells. This review summarized the roles of teichoic acid in the adhesion, colonization and immune regulation of Gram-positive bacteria. The acceptors recognized by the teichoic acid were also discussed. This review will supply new clues for discovering the mechanism of adhesion and colonization of bacteria on the intestinal epithelium cells.

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