综述 Review

细菌素及其在动物生产中的应用

  • 朱双 ,
  • 张爱忠 ,
  • 姜宁 ,
  • 任文 ,
  • 蔡鹏 ,
  • 王法明 ,
  • 穆洋 ,
  • 王立学 ,
  • 张欣鑫
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  • 黑龙江八一农垦大学动物科技学院, 大庆 163319

收稿日期: 2013-08-07

  网络出版日期: 2014-01-27

基金资助

黑龙江省科技厅科技攻关项目(GC10B302);黑龙江省教育厅大学生创新创业训练计划项目(201206)

Bacteriocins and Their Application in Animal Production

  • ZHU Shuang ,
  • ZHANG Aizhong ,
  • JIANG Ning ,
  • REN Wen ,
  • CAI Peng ,
  • WANG Faming ,
  • MU Yang ,
  • WANG Lixue ,
  • ZHANG Xinxin
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  • College of Animal Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China

Received date: 2013-08-07

  Online published: 2014-01-27

摘要

由于抗生素耐药病原菌的出现,一些传染性疾病已难以治疗并且日益恶化。近年来开发新的和有效的抗生素进展缓慢。然而,可替代抗生素的细菌素近些年来备受关注,其在控制抗生素耐药病原菌上拥有巨大的潜力。细菌素是由许多细菌产生的小抗菌肽(AMPs),不仅可以有效地抑制病原体生长,还可以作为益生菌在医疗中发挥重要作用。同时,细菌素作为防腐剂在食品生产中普遍应用,随着人们对畜产品卫生与安全的关注以及益生菌在饲料中的推广应用,细菌素在动物生产中也有着非常广阔的应用前景。为此,本文旨在在介绍细菌素的概念、分类、作用机制的基础上,进一步介绍细菌素在动物生产上的应用。

关键词: 细菌素; 作用机制; 应用

本文引用格式

朱双 , 张爱忠 , 姜宁 , 任文 , 蔡鹏 , 王法明 , 穆洋 , 王立学 , 张欣鑫 . 细菌素及其在动物生产中的应用[J]. 动物营养学报, 2014 , 26(2) : 327 -333 . DOI: 10.3969/j.issn.1006-267x.2014.02.006

Abstract

Due to the emergence of antibiotic-resistant pathogens, some infectious diseases are difficult to treat and are getting worse. In recent years, the development of new and effective antibiotics is slow. However, the alternative antibiotics bacteria are concerned in recent years, which have a great potential to inhibit antibiotic-resistant pathogens by bacteriocins. Bacteriocins are small antimicrobial peptides (AMPS) which are produced by many bacteria, they not only can inhibit effectively pathogen growth, but also can play an important role in health care as probiotics. At the same time, bacteriocins have been commonly used as a preservative in food production. With the focus on health and safety of livestock products as well as popularization and application of probiotics in diet increasing, bacteriocins will be widely used in animal production. This review summarizes the concept, classification, mechanism of bacteriocins, and discusses present research progress about the application of bacteriocins in animal production.

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