本试验旨在研究抗菌肽和姜黄素对1~21日龄肉仔鸡生长性能、免疫器官指数、淋巴细胞转化率和血清免疫球蛋白含量的影响。试验选用1日龄爱拔益加肉仔鸡360只，随机分为5个处理，每个处理6个重复，每个重复12只鸡。对照组饲喂基础饲粮，抗生素组、抗菌肽组、姜黄素组和抗菌肽+姜黄素组分别在基础饲粮中添加35 g/t抗生素、200 g/t抗菌肽、200 g/t姜黄素和200 g/t抗菌肽+200 g/t姜黄素。试验期为21 d。结果表明：1）抗生素组、姜黄素组和抗菌肽+姜黄素组的平均日采食量均极显著高于对照组（P<0.01），抗生素组、抗菌肽组、姜黄素组和抗菌肽+姜黄素组的平均日增重均极显著高于对照组（P<0.01），抗菌肽组的料重比极显著低于对照组（P<0.01）。2）抗菌肽+姜黄素组的免疫器官指数均极显著高于对照组（P<0.01），抗菌肽组的脾脏指数极显著高于对照组（P<0.01），姜黄素组的法氏囊指数极显著高于对照组（P<0.01）。3）抗菌肽组、姜黄素组和抗菌肽+姜黄素组的T淋巴细胞和B淋巴细胞转化率均极显著高于对照组（P<0.01）。4）抗菌肽组和抗菌肽+姜黄素组的血清免疫球蛋白G含量极显著高于对照组（P<0.01）。由此可见，抗菌肽和姜黄素单独或联合使用均能提高肉仔鸡的生长性能和免疫功能，联合使用的效果要优于单独使用，说明抗菌肽和姜黄素之间存在一定的协同作用。

This experiment was conducted to study the effects of antimicrobial peptide and curcumin on growth performance, immune organ indices, lymphocyte transformation rates and serum immunoglobulin contents of broilers aged from 1 to 21 days. A total of 360 one-day-old Arbor Acres (AA) broilers were randomly divided into 5 treatments with 6 replicates per treatment and 12 broilers per replicate. Broilers in the control group were fed a basal diet, and others in antibiotic group, antimicrobial peptide group, curcumin group and antimicrobial peptide+curcumin group were fed the basal diets supplemented with 35 g/t antibiotic, 200 g/t antimicrobial peptide, 200 g/t curcumin and 200 g/t antimicrobial peptide +200 g/t curcumin. The experiment lasted for 21 days.The results showed as follows: 1) the average daily feed intake in antibiotic group, curcumin group and antimicrobial peptide+curcumin group was significantly higher than that in control group (P<0.01), and the average daily gain in antibiotic group, antimicrobial peptide group, curcumin group and antimicrobial peptide+curcumin group was significantly higher than that in control group (P<0.01), while the ratio of feed to gain in antimicrobial peptide group was significantly lower than that in control group (P<0.01). 2) The immune organ indices in antimicrobial peptide+curcumin group were significantly higher than those in control group (P<0.01), the spleen index in antimicrobial peptide group was significantly higher than that in control group (P<0.01), and the bursa of Fabricius index in curcumin group were significantly higher than that in control group (P<0.01). 3) The transformation rates of T and B lymphocyte in antimicrobial peptide group, curcumin group and antimicrobial peptide+curcumin group were significantly higher than those in control group (P<0.01). 4) The serum immunoglobulin G content in antimicrobial peptide group and antimicrobial peptide+curcumin group was significantly higher than that in control group (P<0.01). It is concluded that the addition of antimicrobial peptide and curcumin alone or combined in the diet can improve the growth performance and immune function of broilers. The combination effect is better than alone effect, which is indicate that the combination of antimicrobial peptide and curcumin has a synergistic reaction.