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脱氧雪腐镰刀菌烯醇吸附剂对断奶仔猪生长性能、血清生化指标及肠道形态的影响

  • 邓波 ,
  • 万晶 ,
  • 徐子伟 ,
  • 吴杰
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  • 1. 浙江省农业科学院畜牧兽医研究所, 杭州 310021;
    2. 浙江师范大学化学与生命科学学院, 金华 321004

收稿日期: 2013-11-13

  网络出版日期: 2014-05-05

基金资助

国家生猪产业体系项目(CARS-36-09B)

Effects of Deoxynivalenol Adsorbent on Growth Performance, Serum Biochemical Indexes and Intestinal Morphology of Weaner Piglets

  • DENG Bo ,
  • WAN Jing ,
  • XU Ziwei ,
  • WU Jie
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  • 1. Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China;
    2. College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China

Received date: 2013-11-13

  Online published: 2014-05-05

摘要

本试验旨在研究脱氧雪腐镰刀菌烯醇(deoxynivalenol,DON)污染饲粮中添加DON吸附剂对断奶仔猪生长性能、血清生化指标及肠道形态的影响。选取120头(36±4)日龄断奶仔猪,随机分为3组(每组4个重复,每个重复10头猪),分别为阴性对照(NC)组、DON组(阳性对照)、DON+吸附剂(DON+AD)组,试验期28 d。结果表明:1)试验1~14 d,DON组较NC组平均日增重(ADG)下降21.24%(P<0.05),料重比(F/G)上升15.15%(P<0.05);DON+AD组较DON组ADG提高17.11%(P<0.05),F/G下降10.53%(P<0.05)。试验15~28 d及试验全期各组间ADG和平均日采食量均无显著差异(P>0.05)。2)DON组较NC组血清总蛋白含量显著下降(P<0.05),葡萄糖含量显著上升(P<0.05),DON+AD组较NC组血清葡萄糖、尿素氮含量显著下降(P<0.05)。3)DON组较NC组血清肌酸激酶、谷丙转氨酶活性显著提高(P<0.05),而加入吸附剂后血清肌酸激酶、谷丙转氨酶、谷草转氨酶活性则恢复到正常水平。4)DON组较NC组空肠绒毛高度和绒毛高度/隐窝深度分别下降21.18%和17.97%(P<0.05),DON+AD组较DON组空肠绒毛高度增加16.49%(P<0.05)。因此,DON污染饲粮降低了试验1~14 d断奶仔猪的生长性能,添加DON吸附剂能够改善DON对断奶仔猪生长性能的不利影响,并缓解DON对断奶仔猪所产生的肠道损伤。

本文引用格式

邓波 , 万晶 , 徐子伟 , 吴杰 . 脱氧雪腐镰刀菌烯醇吸附剂对断奶仔猪生长性能、血清生化指标及肠道形态的影响[J]. 动物营养学报, 2014 , 26(5) : 1294 -1301 . DOI: 10.3969/j.issn.1006-267x.2014.05.021

Abstract

This study was conducted to investigate the effects of deoxynivalenol (DON) adsorbent on growth performance, serum biochemical indexes and intestinal morphology of weaner piglets fed DON-contaminated diets. One hundred and twenty weaner piglets at (36±4) days of age were randomly allocated to 3 groups (4 replicates per group and 10 piglets per replicate): negative control (NC) group, DON group (positive control) and DON+adsorbent (DON+AD) group. The trial lasted for 28 days. Results showed as follows: 1) on 1 to 14 days of experiment, compared with NC group, average daily gain (ADG) in DON group was reduced by 21.24% (P<0.05) and feed/gain (F/G) was increased by 15.15% (P<0.05). ADG in DON+AD group was higher by 17.11% than that in DON group (P<0.05) and F/G was lower by 10.53% than that in DON group (P<0.05). On 15 to 28 days of experiment and during the whole trial period, ADG and average daily feed intake were no significant differences among all groups (P>0.05). 2) Compared with NC group, the serum total protein content in DON group was significantly decreased (P<0.05) and glucose content was significantly increased (P<0.05). In DON+AD group, serum glucose and urea nitrogen contents were significantly decreased compared with NC group (P<0.05). 3) Compared with NC group, the serum activities of creatine kinase (CK) and glutamic-pyruvic transaminase (GPT) were significantly increased (P<0.05), while after adding the adsorbent, the serum activities of CK, GPT and glutamic-oxal(o)acetic transaminase (GOT) were returned to normal level. 4) Compared with NC group, the villous height and villous height/crypt depth of jejunum in DON group were decreased by 21.18% and 17.97% (P<0.05), respectively, and DON+AD group had a 16.49% higher jejunum villous height than DON group (P<0.05). It is concluded that the growth performance of piglets fed DON-contaminated diets on 1 to 14 days of experiment is reduced, while DON adsorbent may improve the growth performance of weaner piglets and can alleviate intestine damage induced by DON.

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