动物营养学报 >

2014 , Vol. 26 >Issue 7: 1975 - 1980

DOI: https://doi.org/10.3969/j.issn.1006-267x.2014.07.032

研究简报 Short Communications

半胱胺盐酸盐对泌乳奶牛生产性能和血清激素水平的影响

  • 杨宏波 ,
  • 刘红 ,
  • 陈银岳 ,
  • 陈志远 ,
  • 马婷婷 ,
  • 余同水 ,
  • 刘正旭 ,
  • 赵国琦
展开
  • 扬州大学动物科学与技术学院, 扬州 225009

收稿日期: 2014-01-06

  网络出版日期: 2014-07-01

基金资助

农业部畜牧业质量安全监管项目

收起

Effects of Cysteamine Hydrochloride on Performance and Serum Hormone Levels of Lactating Dairy Cows

  • YANG Hongbo ,
  • LIU Hong ,
  • CHEN Yinyue ,
  • CHEN Zhiyuan ,
  • MA Tingting ,
  • YU Tongshui ,
  • LIU Zhengxu ,
  • ZHAO Guoqi
Expand
  • College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China

Received date: 2014-01-06

  Online published: 2014-07-01

Fold

摘要

本试验旨在确定半胱胺盐酸盐（cysteamine hydrochloride，CSH）在中国荷斯坦奶牛饲粮中的适宜添加量。选择产奶量、泌乳日龄、胎次相近的荷斯坦泌乳奶牛48头，分为6组，每组8头，分别在饲粮中添加0（对照组）、15、30、75、150和300 g/d的CSH，预试期14 d，正试期56 d，测定奶牛生产性能和血清激素水平。结果表明：奶牛的平均日采食量、平均日产奶量和4%标准乳产量在CSH添加量为75 g/d时最高，之后随着CSH添加量的升高而逐渐下降，且15~150 g/d组平均日采食量与对照组相比无显著差异（P>0.05），300 g/d组平均日采食量最低；乳脂率和乳总固形物含量在CSH添加量为75 g/d时最高，且其他试验组和对照组相比差异不显著（P>0.05）；乳尿素氮含量随着CSH添加量的升高而逐渐下降，且添加量为300 g/d时最低。当CSH添加量为15 g/d时，血清生长激素和甲状腺素含量显著高于对照组（P<0.05），添加量为30 g/d时，血清生长激素和三碘甲状腺原氨酸含量显著高于对照组（P<0.05）。综上所述，在中国荷斯坦奶牛饲粮中CSH的添加量以15~75 g/d为宜。

关键词： 半胱胺盐酸盐; 奶牛; 生产性能; 血清激素

本文引用格式

杨宏波 , 刘红 , 陈银岳 , 陈志远 , 马婷婷 , 余同水 , 刘正旭 , 赵国琦 . 半胱胺盐酸盐对泌乳奶牛生产性能和血清激素水平的影响[J]. 动物营养学报, 2014 , 26(7) : 1975 -1980 . DOI: 10.3969/j.issn.1006-267x.2014.07.032

Abstract

The objective of this study was to determine the optimal supplemental level of cysteamine hydrochloride (CSH) in diets for lactating Holstein dairy cows. Forty-eight healthy Holstein dairy cows, similarly in milk yield, days in lactation and parity, were allocated into six groups in a randomized complete block design with eight cows per group. Cows were supplemented with CSH at 0 (control group), 15, 30, 75, 150 and 300 g/d in the basal diet. The pre-experimental period lasted for 14 days, and the experimental period lasted for 56 days. The performance and serum hormone levels of cows were detected. The results showed that average daily feed intake (ADFI), average daily milk production and 4% fat corrected milk yield were the highest when supplemented with 75 g/d CSH, then those indices were decreased with the increase of CSH supplemental level, while there was no significant difference in ADFI between 15 to 150 g/d groups and control group (P>0.05), and 300 g/d group had the lowest ADFI; milk fat percentage and milk total solids content were the highest when supplemented with 75 g/d CSH, and there were no significant differences between other experimental groups and control group (P>0.05); milk urea nitrogen content was decreased with the increase of CSH supplemental level, and 300 g/d group was the lowest. When supplemented with 15 g/d CSH, serum growth hormone (GH) and thyroxine contents were significantly higher than those in the control group (P<0.05); and when supplemented with 30 g/d CSH, serum GH and triiodothyronine contents were significantly higher than those in control group (P<0.05). In conclusion, the optimal supplemental level of CSH for Chinese Holston dairy cows is 15 to 75 g/d.

Key words： cysteamine hydrochloride; cows; performance; serum hormone

参考文献

[1] VAZQUEZ-ANON M,BERTICS S J,GRUMMER R R.The effect of dietary energy source during mid to late lactation on liver triglyceride and lactation performance of dairy cows[J].Dairy Science,1997,80(10):2504-2512.  
[2] 沈赞明,张荣飞,解红梅,等.半胱胺盐酸盐对泌乳20-42周奶牛产奶性能和部分免疫指标的影响[J].畜牧兽医学报,2005,36(7):667-673.
[3] MILLAD W J,SAGAR S M,MARTIN J B.Cysteamine-induced depletion of somatostatin and prolactin[J].Federation Proceeding,1988,44(9):2546-2550.
[4] MCLEOD K R,HARMON D L,SCHILLO K K,et al.Cysteamine-induced depletion of somatostatin in sheep:time course of depletion and changes in plasma metabolites,insulin,and growth hormone[J].Animal Science,1995,73(1):77-87.
[5] 艾晓杰,韩正康,陈伟华.口服半胱胺对绵羊血浆中生长抑素和几种代谢激素的影响[J].畜牧兽医学报,2001,32(6):505-509.
[6] SAGAR S M,LANDRY D,MILLARD W J,et al.Depletion of somatostatin like immunoreactivity in the rat central nervous system by cysteamine[J].Journal of Endocrinology,1982,2(2):225-231.
[7] WILLIAM J M,STEPHEN M S,THOMAS M B,et al.The effects of csteamine on tyrotropin and immunoreactive beta-endoph insecretion in the rat[J].Endocrinology,1983,112:509-513.
[8] 韩剑众.生长抑素抑制剂--半胱胺作为饲料添加剂的研究[J].饲料研究,2000(8):8-9.
[9] WIDMANN R,SPERK C.Cysteamine-induced decrease of somatostatin in rat brain synaptosornes in vitro[J].Endocrinology,1987,121(4):1383-1389.  
[10] YANG C B,LI A K,YIN Y L,et al.Effects of dietary supplementation of cysteamine on growth performance,carcass quality,serum hormones and gastric ulcer in finishing pigs[J].Journal of the Science of Food and Agriculture,2005,85(11):1947-1952.  
[11] 王艳玲,李振田,董秀钿,等.半胱胺对奶牛产奶量及血浆生长抑素、生长激素水平的影响[J].中国畜牧杂志,1999,35(6):14-15.
[12] 王黎文,丁健,张建刚,等.霉菌毒素吸附剂蒙脱石对泌乳奶牛生产性能和血清生化指标的影响[J].动物营养学报,2013,25(7):1595-1602.
[13] 张丽英.饲料分析及饲料质量检测技术[M].3版.北京:中国农业大学出版社,2007:48-96.
[14] 杨佳栋,李建国,李英,等.半胱胺对肉牛生产性能和养分消化率及血清生化指标的影响[J].动物营养学报,2006,18(4):261-266.
[15] LIU G M,WANG Z S,WU D,et al.Effects of dietary cysteamine supplementation on growth performance and whole-body protein turnover in finishing pigs[J].Livestock Science,2009,122(1):86-89.  
[16] DUNSHEA F R.Porcine somatotropin and cysteamine hydrochloride improve growth performance and reduce back fat in finisher gilts[J].Australian Journal of Experimental Agriculture,2007,47(7):796-800.  
[17] 韩正康,刘宗柱,沈延法.半胱胺引起绵羊外周血液β-内啡肽和几种主要代谢激素的变化[J].畜牧兽医学报,1996,27(3):193-198.
[18] 韩剑众,葛长荣.半胱胺对黄羽肉鸡生长及内分泌的影响[J].中国家禽,2000,22(11):12-13.
[19] 高腾云,王艳玲,韩正康,等.半胱胺对肉牛增重、采食量和血液激素水平的影响[J].华中农业大学学报,2001,20(3):259-261.
[20] TERRY L C,CRAIG R.Cysteamine effects on monoamines,dopamine-β-hydroxylase and the hypothalamic-pituitary axis[J].Neuroendoerinology,1985,41(6):467-475.  
[21] MILLARD W J,SAGAR S M,BADGER T M,et al.The effects of cystemine on thyrotropin and immunoreactive beta-endophin secretion in the rat[J].Endoerinology,1983,112(2):518-525.  
[22] 夏伦志,蔡东,熊国远,等.半胱胺补饲模式对奶牛生产性能及血清胰岛素水平的影响[J].中国畜牧杂志,2005,41(2):27-29.
[23] MCLEOD K R,HARMON D L,SCHILLO K K,et al.Effects of cysteamine on pulsatile growth hormone release and plasma insulin concentrations in sheep[J].Comparative Biochemistry and Physiology Part B:Biochemistry and Molecular Biology,1995,112(3):523-533.  
[24] WAKABAYASHI I,TONEGAWA Y,SHIBASAKI T,et al.Effect of dopamine,bombesin and cysteamine hydrochloride on plasma growth hormone response to synthetic growth hormone-releasing factor in rats[J].Life Sciences,1985,36(15):1437-1443.  
[25] MILLARD W J,SAGAR S M,BADGER T M,et al.Cysteamine effects on growth hormone secretion in the male rat[J].Endocrinology,1983,112(2):509-517.  
[26] FUKUHARA S,SUZUKI H.Enhanced ghrelinsecretion in rats with cysteamine-induced duodenal ulcers[J].Gastrointestinal and Liver Physiology,2005,289(1):138-145.  
[27] KAPUSCINSKI M,SHULKES A,GREEN M,et al.Cysteamine can induce duodenal ulceration in rats without depletion of immunoreactive somatostatin[J].Regulatory Peptides,1991,36(3):391-406.  
Options
文章导航

/

〈 〉

    联系我们

  • 地址：北京市海淀区圆明园西路2号
    　　　中国农业大学动科动医大楼153室
  • 邮编：100193
  • 电话：010－62817823
  • 网址：http://www.chinajan.com
  • E-mail：cjan@chinajan.com
京公网安备 11010802041926号    京ICP备17050989号-2