研究简报 Short Communications

黄芪多糖对肉鸡免疫应激状态下蛋白质重分配的影响

  • 刘磊 ,
  • 苏满春 ,
  • 雷耀庚 ,
  • 赵超 ,
  • 王卫涛 ,
  • 姚军虎 ,
  • 龚月生 ,
  • 杨小军
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  • 西北农林科技大学动物科技学院, 杨凌 712100

收稿日期: 2014-06-09

  网络出版日期: 2014-12-05

基金资助

国家自然科学基金项目(31272464,31001017);教育部新世纪优秀人才支持计划(NCET-12-0476);留学人员科技活动择优资助项目(2012YX-02)

Effects of Astragalus Polysaccharide on Protein Reallocation of Broilers Exposed to Immune Stress

  • LIU Lei ,
  • SU Manchun ,
  • LEI Yaogeng ,
  • ZHAO Chao ,
  • WANG Weitao ,
  • YAO Junhu ,
  • GONG Yuesheng ,
  • YANG Xiaojun
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  • College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China

Received date: 2014-06-09

  Online published: 2014-12-05

摘要

本试验旨在研究饲粮添加黄芪多糖对大肠杆菌(O55:B5)脂多糖诱导的肉鸡免疫应激状态下蛋白质重分配的调节作用.试验采用2×2双因素设计将1日龄爱拔益加肉鸡144只随机分为4组,每组6个重复,每个重复6只鸡.2个试验因素分别为:免疫应激(注射生理盐水或脂多糖)和饲粮黄芪多糖(0或3 g/kg).21~35日龄进行蛋白质沉积试验.结果显示,免疫应激显著降低了肉鸡平均日采食量、平均日增重、左侧胸肌的蛋白质沉积量及沉积率(P<0.05),同时显著提高了脾脏指数、脾脏蛋白质沉积量和脾脏、法氏囊的蛋白质沉积率(P<0.05).而饲粮添加黄芪多糖可使肉鸡在免疫应激时,平均日采食量和平均日增重分别提高16.30%和18.34%,左侧胸肌的蛋白质沉积量和沉积率分别提高30.36%和12.34%,且显著抑制了脾脏蛋白质沉积量和沉积率的上升(P<0.05).综上所述,在肉鸡免疫应激状态下,饲粮中添加3 g/kg黄芪多糖可抑制蛋白质从骨骼肌向免疫系统重分配,缓解肉鸡生长抑制.

本文引用格式

刘磊 , 苏满春 , 雷耀庚 , 赵超 , 王卫涛 , 姚军虎 , 龚月生 , 杨小军 . 黄芪多糖对肉鸡免疫应激状态下蛋白质重分配的影响[J]. 动物营养学报, 2014 , 26(12) : 3799 -3805 . DOI: 10.3969/j.issn.1006-267x.2014.12.033

Abstract

This study was conducted to investigate the effects of Astragalus polysaccharide (APS) on protein reallocation in broilers after challenge with E.coli (O55:B5) lipopolysaccharide (LPS). A total of 144 one-day-old Arbor Acres broilers were randomly divided into four groups (six replicates per group and six birds per replicate) in terms of a 2×2 factorial design. The main factors were immune stress (LPS or saline injection) and dietary APS (0 or 3 g/kg). A trial of protein deposition was performed from 21 to 35 days of age. The results showed that immune stress significantly reduced average daily feed intake (ADFI), average daily gain (ADG), protein deposition (PD) and protein deposition rate (PDR) of the left pectoralis (P<0.05). Meanwhile, the spleen index, spleen PD, spleen and bursa of fabricius PDRs were significantly increased by immune stress (P<0.05). Under immune stress, however, ADFI and ADG were increased by 16.30% and 18.34% respectively via dietary APS supplementation. The left pectoralis PD and PDR were increased by 30.36% and 12.34% respectively as well. The elevated spleen PD and PDR caused by immune stress were significantly decreased by dietary APS supplementation (P<0.05). In conclusion, dietary supplementation with 3 g/kg APS can inhibit protein redistribution from skeletal muscle to the immune system, and attenuate growth inhibition caused by immune stress.

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