谭敏捷 , 孔祥峰 , 刘庆友 , 石德顺 . 多胺与哺乳动物的孕体发育[J]. 动物营养学报, 2015 , 27(1) : 43 -48 . DOI: 10.3969/j.issn.1006-267x.2015.01.007

[1] 易星,莫远亮,姜冬梅,等.多胺的生物学功能及其调控机制[J].动物营养学报,2014,26(2):348-352.

[2] LARQUÉ E,SABATER-MOLINA M,ZAMORA S.Biological significance of dietary polyamines[J].Nutrition,2007,23(1):87-95.  

[3] WU G,FLYNN N E,KNABE D A.Enhanced intestinal synthesis of polyamines from proline in cortisol-treated piglets[J].American Journal of Physiology:Endocrinology and Metabolism,2000,279(2):E395-E402.

[4] WANG X Q,YING W,DUNLAP K A,et al.Arginine decarboxylase and agmatinase:an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses[J].Biology of Reproduction,2014,90(4):84.

[5] CUI X S,KIM N H.Polyamines inhibit apoptosis in porcine parthenotes developing in vitro[J].Molecular Reproduction and Development,2005,70(4):471-477.  

[6] PARK M H,NISHIMURA K,ZANELLI C F,et al.Functional significance of eIF5A and its hypusine modification in eukaryotes[J].Amino Acids,2010,38(2):491-500.  

[7] BAZER F W,WU G Y,SPENCER T E,et al.Novel pathways for implantation and establishment and maintenance of pregnancy in mammals[J].Molecular Human Reproduction,2010,16(3):135-152.  

[8] DESMARAIS J A,BORDIGNON V,LOPES F L,et al.The escape of the mink embryo from obligate diapause[J].Biology of Reproduction,2004,70(3):662-670.

[9] LEFÈVRE P L C,PALIN M F,CHEN G,et al.Polyamines are implicated in the emergence of the embryo from obligate diapause[J].Endocrinology,2011,152(4):1627-1639.  

[10] RAMATHAL C Y,BAGCHI I C,TAYLOR R N,et al.Endometrial decidualization:of mice and men[J].Seminars in Reproductive Medicine,2010,28(1):17-26.  

[11] LEFÈVRE P L C,PALIN M F,MURPHY B D.Polyamines on the reproductive landscape[J].Endocrine Reviews,2011,32(5):694-712.  

[12] ZHAO Y C,CHI Y J,YU Y S,et al.Polyamines are essential in embryo implantation:expression and function of polyamine-related genes in mouse uterus during peri-implantation period[J].Endocrinology,2008,149(5):2325-2332.  

[13] RODRIGUEZ-SALLABERRY C,SIMMEN F A,SIMMEN R C.Polyamine- and insulin- like growth factor-Ⅰ-mediated proliferation of porcine uterine endometrial cells:a potential role for spermidine/spermine N1-acetyltransferase during peri-implantation[J].Biology of Reproduction,2001,65(2):587-594.  

[14] GAO H J,WU G,SPENCER T E,et al.Select nutrients in the ovine uterine lumen.Ⅴ.Nitric oxide synthase,GTP cyclohydrolase,and ornithine decarboxylase in ovine uteri and peri-implantation conceptuses[J].Biology of Reproduction,2009,81(1):67-76.  

[15] LOPEZ-GARCIA C,LOPEZ-CONTRERAS A J,CREMADES A,et al.Transcriptomic analysis of polyamine-related genes and polyamine levels in placenta,yolk sac and fetus during the second half of mouse pregnancy[J].Placenta,2009,30(3):241-249.  

[16] BAZER F W,KIM J,KA H,et al.Select nutrients in the uterine lumen of sheep and pigs affect conceptus development[J].Journal of Reproduction and Development,2012,58(2):180-188.  

[17] WU G Y,BAZER F W,DAVIS T A,et al.Arginine metabolism and nutrition in growth,health and disease[J].Amino Acids,2009,37(1):153-168.  

[18] KIM J Y,BURGHARDT R C,WU G,et al.Select nutrients in the ovine uterine lumen.Ⅷ.arginine stimulates proliferation of ovine trophectoderm cells through MTOR-RPS6K-RPS6 signaling cascade and synthesis of nitric oxide and polyamines[J].Biology of Reproduction,2011,84(1):70-78.  

[19] REYNOLDS L P,CATON J S,REDMER D A,et al.Evidence for altered placental blood flow and vascularity in compromised pregnancies[J].The Journal of Physiology,2006,572(Pt 1):51-58.

[20] LÔPEZ-GARCÍA C,LÔPEZ-CONTRERAS A J,CREMADES A,et al.Molecular and morphological changes in placenta and embryo development associated with the inhibition of polyamine synthesis during midpregnancy in mice[J].Endocrinology,2008,149(10):5012-5023.  

[21] WANG X J,IKEGUCHI Y,MCCLOSKEY D E,et al.Spermine synthesis is required for normal viability,growth,and fertility in the mouse[J].The Journal of Biological Chemistry,2004,279(49):51370-51375.  

[22] MANEN C A,HOOD R D,FARINA J.Ornithine decarboxylase inhibitors and fetal growth retardation in mice[J].Teratology,1983,28(2):237-242.  

[23] ISHIDA M,HIRAMATSU Y,MASUYAMA H,et al.Inhibition of placental ornithine decarboxylase by DL-α-difluoro-methyl ornithine causes fetal growth restriction in rat[J].Life Sciences,2002,70(12):1395-1405.  

[24] SATTERFIELD M C,BAZER F W,SPENCER T E,et al.Sildenafil citrate treatment enhances amino acid availability in the conceptus and fetal growth in an ovine model of intrauterine growth restriction[J].The Journal of Nutrition,2010,140(2):251-258.  

[25] JOBGEN W S,FORD S P,JOBGEN S C,et al.Baggs ewes adapt to maternal undernutrition and maintain conceptus growth by maintaining fetal plasma concentrations of amino acids[J].Journal of Animal Science,2008,86(4):820-826.  

[26] KWON H,FORD S P,BAZER F W,et al.Maternal nutrient restriction reduces concentrations of amino acids and polyamines in ovine maternal and fetal plasma and fetal fluids[J].Biology of Reproduction,2004,71(3):901-908.  

[27] KWON H,WU G Y,BAZER F W,et al.Developmental changes in polyamine levels and synthesis in the ovine conceptus[J].Biology of Reproduction,2003,69(5):1626-1634.  

[28] GILAD G M,GILAD V H.Novel polyamine derivatives as neuroprotective agents[J].The Journal of Pharmacology and Experimental Therapeutics,1999,291(1):39-43.

[29] MARTÍN I,GIBERT M J,PINTOS C,et al.Oxidative stress in mothers who have conceived fetus with neural tube defects:the role of aminothiols and selenium[J].Clinical Nutrition,2004,23(4):507-514.  

[30] HAGHIGHI P S,ALHONEN L,SALONURMI T,et al.Ethanol-induced impairment of polyamine homeostasis-A potential cause of neural tube defect and intrauterine growth restriction in fetal alcohol syndrome[J].Biochemical and Biophysical Research Communications,2014,446(1):173-178.  

[31] WU G,BAZER F W,BURGHARDT R C,et al.Impacts of amino acid nutrition on pregnancy outcome in pigs:mechanisms and implications for swine production[J].Journal of Animal Science,2010,88(13 electronic suppl):E195-E204.