综述 Review

胚胎营养环境对动物出生后营养代谢的调控研究

  • 吕佳琪 ,
  • 华雯妤 ,
  • 王恬
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  • 1. 南京农业大学动物科技学院, 南京 210095;
    2. 济南磐升生物技术有限公司, 济南 250000

收稿日期: 2015-09-28

  网络出版日期: 2016-02-19

基金资助

国家重点基础研究发展计划(973)(2012CB124703)

Effects of Embryonic Nutrition Environment on the Nutritional Metabolism after Birth

  • LYU Jiaqi ,
  • HUA Wenyu ,
  • WANG Tian
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  • 1. Institution of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China;
    2. Jinan Pansheng Biotechnology Limited Company, Jinan 250000, China

Received date: 2015-09-28

  Online published: 2016-02-19

摘要

动物胚胎营养环境受母体营养供应与胎盘营养转运2个方面的影响。充足、合理的母体营养供应是胚胎健康发育的保障。胎盘负责转运来自母体的营养,转运的效率决定了胚胎的营养供给。胚胎的发育与所处的营养环境密不可分,不利的胚胎营养环境可以程序化胚胎发育,并持续影响代谢,导致动物成年发生慢性疾病。因此,深入研究母体营养供应对后代代谢的长期影响,有助于后代的健康生长,还可有效降低动物出生后代谢疾病的发生率。本文梳理了母体营养供应不足对动物出生后营养代谢的影响,初步综述了营养程序化的发生机制。

本文引用格式

吕佳琪 , 华雯妤 , 王恬 . 胚胎营养环境对动物出生后营养代谢的调控研究[J]. 动物营养学报, 2016 , 28(2) : 335 -344 . DOI: 10.3969/j.issn.1006-267x.2016.02.005

Abstract

Fetal nutrition is under the influence of both the maternal nutrition supply and placental nutrition transport. Adequate and appropriate maternal nutrition supply is the guarantee of healthy fetal development. The placenta is responsible for nutrient transport. The nutrition supply for the fetal depends on the efficiency of the transfer. Fetal development is closely connected with the embryonic environment. Adverse fetal environment can programme the embryonic development, cause lasting effects on the metabolism, and lead to chronic disease in adulthood. Therefore, the study of long-term effects of maternal nutrition supply will contribute to the health of future generations, and effectively reduce the incidence of adult metabolic diseases. This article introduced the influence of poor fetal nutrition on the metabolism of offspring, and discussed the mechanisms of nutritional programming.

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