本研究探讨了饲粮中添加鹅脱氧胆汁酸（CDCA）对种鸡脂代谢、生产性能及子代肌肉发育的影响。试验选用14周龄矮脚黄种鸡80只，随机分为5个组，每组16个重复，每个重复1只鸡。对照组饲喂基础饲粮，试验组在基础饲粮中分别添加10、50、100和500 mg/kg的CDCA，试验期4周。在试验最后1周收集种蛋进行孵化，出雏后的子代根据种鸡分组情况分为5组，饲养期12周。结果表明：1）饲粮中添加CDCA对种鸡的体重、产蛋率和蛋品质均无显著影响（P>0.05）；与对照组相比，饲粮中添加100 mg/kg的CDCA能够显著增加种鸡血清中甘油三酯（TG）含量（P<0.05），显著降低血清中极低密度脂蛋白（VLDL）含量（P<0.05）；与对照组相比，饲粮中添加100 mg/kg的CDCA能够显著降低试验第14天和第28天种鸡蛋内总胆汁酸（TBA）含量（P<0.05），显著增加蛋内胆固醇（TC）和低密度脂蛋白胆固醇（LDL-C）含量（P<0.05）。2）与对照组相比，饲粮中添加50 mg/kg的CDCA能够显著增加子代腓肠肌肌纤维密度和子代公鸡肝脏率（P<0.05），饲粮中添加100 mg/kg的CDCA能够显著降低子代母鸡的平均日增重、子代公鸡腓肠肌总蛋白沉积量和子代母鸡腓肠肌中乳酸脱氢酶（LDH）活性（P<0.05），饲粮中添加500 mg/kg的CDCA能够显著降低子代母鸡腓肠肌琥珀酸脱氢酶（SDH）活性和子代公鸡腓肠肌LDH活性（P<0.05）。由此可见，饲粮中添加CDCA对种鸡的生产性能无显著影响，但会影响种鸡的脂代谢以及蛋内沉积特别是TBA的沉积，进而对子代肌肉发育产生抑制作用，因此CDCA在种鸡饲粮中的应用应注意添加剂量以及使用时间。

This experiment was conducted to investigate the effects of dietary chenodexycholic acids (CDCA) on lipid metabolism and performance of breeding hens and muscle development of their offspring. Eighty 14-weeks-old dwarf yellow breeding hens were randomly divided into 5 groups with 16 replicates per group and 1 bird per replicate. Breeding hens in the control group were fed a basal diet, and the others in experimental groups were fed the diets supplemented with 10, 50, 100 and 500 mg/kg CDCA for 4 weeks, respectively. Fertilized eggs were collected and hatch in the last week, and the offspring after hatching were divided into 5 groups just as the breeding hens. Feeding trial lasted for 12 weeks. The results showed as follows:1) dietary CDCA had no significant effects on body weight, laying rate and egg qualities of breeding hens (P>0.05). Compared with the control group, supplement of 100 mg/kg CDCA significantly increased the serum triglyceride (TG) content of breeding hens (P<0.05), and significantly decreased the serum very low density lipoprotein (VLDL) content (P<0.05). Compared with the control group, supplement of 100 mg/kg CDCA significantly decreased the total bile acid (TBA) content in ovo of breeding hens at 14 and 18 days (P<0.05), and significantly increased the contents of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) in ovo (P<0.05). 2) Compared with the control group, supplement of 50 mg/kg CDCA significantly increased fiber density of gastrocnemius of offspring and liver percentage of male offspring (P<0.05), supplement of 100 mg/kg CDCA significantly decreased the average daily gain of female offspring, total protein deposition of gastrocnemius of male offspring and the activity of lactate dehydrogenase (LDH) of gastrocnemius of female offspring (P<0.05), supplement of 500 mg/kg CDCA significantly decreased the activity of succinate dehydrogenase (SDH) of gastrocnemius of female offspring and the activity of LDH of gastrocnemius of male offspring (P<0.05). In conclusion, dietary CDCA has no significant effect on performance of breeding hens, but has significant effects on lipid metabolism and deposition in vov especially TBA deposition, and then suppress the muscle development of their offspring. Therefore, the dosage and the time of CDCA in the diet of breeding hens should be noticed.