[1] LYAKHOVICH V V,VAVILIN V A,ZENKOV N K,et al.Active defense under oxidative stress.The antioxidant responsive element[J].Biochemistry,2006,71(9):962-974.
[2] DINKOVA-KOSTOVA A T,TALALAY P.Direct and indirect antioxidant properties of inducers of cytoprotective proteins[J].Molecular Nutrition & Food Research,2008,52(Suppl.1):S128-S138.
[3] HOLTZCLAW W D,DINKOVA-KOSTOVA A T,TALALAY P.Protection against electrophile and oxidative stress by induction of phase 2 genes:the quest for the elusive sensor that responds to inducers[J].Advances in Enzyme Regulation,2004,44(1):335-367.
[4] STEWART J D,HENGSTLER J G,BOLT H M.Control of oxidative stress by the Keap1-Nrf2 pathway[J].Archives of Toxicology,2011,85:239.
[5] TAGUCHI K,MOTOHASHI H,YAMAMOTO M.Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution[J].Genes to Cells,2011,16(2):123-140.
[6] 马燕芬,宋利文,高民,等.氧化应激对围产期奶牛乳房炎的影响及其调控机制[J].动物营养学报,2015,27(3):671-676.
[7] SURH Y J,KUNDU J K,NA H K.Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals[J].Planta Medica,2008,74(13):1526-1539.
[8] KUNDU J K,SURH Y J.Inflammation:gearing the journey to cancer[J].Mutation Research/Reviews in Mutation Research,2008,659(1/2):15-30.
[9] MA Q.Transcriptional responses to oxidative stress:pathological and toxicological implications[J].Pharmacology & Therapeutics,2010,125(3):376-393.
[10] COPPLE I M.The Keap1-Nrf2 cell defense pathway-a promising therapeutic target?[J].Advances in Pharmacology,2012,63:43-79.
[11] MAGESH S,CHEN Y,HU L Q.Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents[J].Medicinal Research Reviews,2012,32(4):687-726.
[12] CHO H Y,REDDY S P,KLEEBERGER S R.Nrf2 defends the lung from oxidative stress[J].Antioxidants & Redox Signaling,2006,8(1/2):76-87.
[13] KEUM Y S,JEONG W S,KONG A N T.Chemoprevention by isothiocyanates and their underlying molecular signaling mechanisms[J].Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis,2004,555(1/2):191-202.
[14] KEUM Y S.Regulation of Nrf2-mediated phase Ⅱ detoxification and anti-oxidant genes[J].Biomolecules and Therapeutics (Seoul),2012,20(2):144-151.
[15] NITURE S K,JAIN A K,JAISWAL A K.Antioxidant-induced modification of INrf2 cysteine 151 and PKC-δ-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance[J].Journal of Cell Science,2009,122(24):4452-4464.
[16] JAIN A K,JAISWAL A K.Phosphorylation of tyrosine 568 controls nuclear export of Nrf2[J].The Journal of Biological Chemistry,2006,281(17):12132-12142.
[17] LIBY K T,SPORN M B.Synthetic oleanane triterpenoids:multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease[J].Pharmacological Reviews,2012,64(4):972-1003.
[18] SCANNEVIN R H,CHOLLATE S,JUNG M Y,et al.Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway[J].The Journal of Pharmacology and Experimental Therapeutics,2012,341(1):274-284.
[19] 杨光照.EGCG通过上调Nrf2/HO-1途径降低PM2.5所致HUVEC氧化损伤的机制研究[D].博士学位论文.太原:山西医科大学,2015.
[20] FAROMBI E O,SHROTRIYA S,NA H K,et al.Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1[J].Food and Chemical Toxicology,2008,46(4):1279-1287.
[21] ZHONG J L,EDWARDS G P,RAVAL C,et al.The role of Nrf2 in ultraviolet a mediated heme oxygenase 1 induction in human skin fibroblasts[J].Photochemical & Photobiological Science,2010,9(1):18-24.
[22] OKOUCHI M,OKAYAMA N,ALEXANDER J S,et al.NRF2-dependent glutamate-L-cysteine ligase catalytic subunit expression mediates insulin protection against hyperglycemia-induced brain endothelial cell apoptosis[J].Current Neurovascular Research,2006,3(4):249-261.
[23] 蒋怡芳.白藜芦醇对过氧化氢诱导的原代脊髓星形胶质细胞毒性的保护作用[D].硕士学位论文.石家庄:河北医科大学,2009.
[24] 鲍兵.莱菔硫烷激活Nrf2-ARE通路拮抗PC12细胞氧化应激损伤的机制研究[D].硕士学位论文.南昌:南昌大学,2013.
[25] WANG X J,HAYES J D,HENDERSON C J,et al.Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[J].Proceedings of the National Academy of Sciences of the United States of America,2007,104(49):19589-19594.
[26] TANG X W,WANG H Y,FAN L F,et al.Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs[J].Free Radical Biology and Medicine,2011,50(11):1599-1609.
[27] OHNUMA T,MATSUMOTO T,ITOI A,et al.Enhanced sensitivity of A549 cells to the cytotoxic action of anticancer drugs via suppression of Nrf2 by procyanidins from cinnamomi cortex extract[J].Biochemical and Biophysical Research Communications,2011,413(4):623-629.
[28] GAO A M,KE Z P,WANG J N,et al.Apigenin sensitizes doxorubicin-resistant hepatocellular carcinoma BEL-7402/ADM cells to doxorubicin via inhibiting PI3K/Akt/Nrf2 pathway[J].Carcinogenesis,2013,34(8):1806-1814.
[29] GAO A M,KE Z P,SHI F,et al.Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway[J].Chemico-Biological Interactions,2013,206(1):100-108.
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