动物营养学报 >

2017 , Vol. 29 >Issue 6: 2092 - 2099

DOI: https://doi.org/10.3969/j.issn.1006-267x.2017.06.031

研究简报 Short communications

芪楂口服液药渣发酵前后对断奶仔猪血浆生化参数和抗氧化能力的影响

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  • 1. 河南科技大学, 动物科技学院, 洛阳 471003;
    2. 中国科学院亚热带农业生态研究所, 湖南省畜禽健康养殖工程技术研究中心, 农业部中南动物营养与饲料科学观测实验站, 长沙 410125;
    3. 湖南省植物功能成分利用协同创新中心, 长沙 410128;
    4. 浏阳市畜牧兽医水产局, 浏阳 410300
苏家宜(1992-),女,河南新乡人,硕士研究生,从事猪营养生理研究。E-mail:sjy19920406@126.com

收稿日期: 2016-12-01

  网络出版日期: 2017-06-07

基金资助

湖南省战略性新兴产业科技攻关项目（2014GK1007）；中央驻湘科研机构技术创新发展专项（2013TF3006）；中国工程院咨询研究项目（2015-XY-41）

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Effects of Qi-Zha Oral Solution Residues and Fermented Qi-Zha Oral Solution Residues on Plasma Biochemical Parameters and Antioxidant Ability of Weaned Piglets

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  • 1. College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China;
    2. Hunan Provincial Engineering Research Center of Healthy Livestock, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;
    3. Hunan Co-Innovation Center of Utilizing Plant Functional Components, Changsha 410128, China;
    4. Animal Husbandry and Veterinary Bureau of Liuyang City, Liuyang 410300, China

Received date: 2016-12-01

  Online published: 2017-06-07

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摘要

为了探讨中药渣用于断奶仔猪养殖的可行性，比较研究了芪楂口服液药渣发酵前和发酵后对断奶仔猪血浆生化参数和抗氧化能力的影响。试验选用21日龄断奶仔猪120头，随机分为4组，分别为空白对照组（不添加抗生素和氧化锌）、芪楂口服液药渣组（添加5 kg/t芪楂口服液药渣）、发酵芪楂口服液药渣组（添加5 kg/t发酵芪楂口服液药渣）和阳性对照组（添加0.04 kg/t维吉尼亚霉素+0.2 kg/t硫酸黏杆菌素+3 000 mg/kg氧化锌），每组5个重复，每个重复6头仔猪。试验期28 d。分别于试验第7和28天采血并测定血浆生化参数和抗氧化指标。结果表明:试验第7天，发酵芪楂口服液药渣组血浆总蛋白（TP）和球蛋白（GLB）含量显著高于2个对照组（P<0.05），白蛋白/球蛋白（ALB/GLB）值显著低于2个对照组（P<0.05），天冬氨酸氨基转移酶活性显著低于空白对照组（P<0.05），碱性磷酸酶活性显著低于芪楂口服液药渣组和阳性对照组（P<0.05），甘油三酯含量显著高于阳性对照组（P<0.05）；试验第28天，芪楂口服液药渣组血浆TP、总胆固醇含量显著高于阳性对照组（P<0.05），ALB/GLB值显著低于阳性对照组（P<0.05），发酵芪楂口服液药渣组血浆高密度脂蛋白胆固醇含量和超氧化物歧化酶（SOD）活性显著低于芪楂口服液药渣组（P<0.05），谷胱甘肽过氧化物酶（GSH-Px）活性显著低于芪楂口服液药渣组和空白对照组（P<0.05）。与试验第7天相比，试验第28天芪楂口服液药渣组血浆过氧化氢酶活性、发酵芪楂口服液药渣组血浆TP和GLB含量以及GSH-Px活性显著降低（P<0.05），2个对照组血浆TP、GLB和ALB含量均显著降低（P<0.05），芪楂口服液药渣组血浆SOD活性、发酵芪楂口服液药渣组和阳性对照组的ALB/GLB值均显著升高（P<0.05）。综上所述，饲粮添加芪楂口服液药渣可以提高仔猪免疫力，芪楂口服液药渣发酵前后均对肝脏无不利影响，可作为饲料添加剂用于养猪生产。

关键词： 芪楂口服液药渣; 发酵; 断奶仔猪; 生化参数; 抗氧化能力

本文引用格式

苏家宜, 孔祥峰, 胡诚军, 解培峰, 印遇龙, 王志平, 王占彬 . 芪楂口服液药渣发酵前后对断奶仔猪血浆生化参数和抗氧化能力的影响[J]. 动物营养学报, 2017 , 29(6) : 2092 -2099 . DOI: 10.3969/j.issn.1006-267x.2017.06.031

Abstract

The present study was conducted to determine the effects of Qi-Zha oral solution residues (QOR) and their fermented product on plasma biochemical parameters and antioxidant ability of weaned piglets, to explore the feasibility of dietary supplementation with herbal residues. A total of 120 piglets weaned at 21 days of age were randomly assigned to one of four groups with five replicates per group and six piglets per replicate, representing blank control group (without adding antibiotics and zinc oxide), QOR group (supplemented with 5 kg/t QOR), fermented QOR group (supplemented with 5 kg/t fermented QOR) and positive control group (supplemented with 0.04 kg/t virginiamycin+0.2 kg/t colimycin+3 000 mg/kg zinc oxide). The experiment lasted for 28 days, and at the 7th and 28th day of the experiment, the blood samples were collected, respectively, for determining biochemical parameters and antioxidant indices. The results showed that, at the 7th day of the experiment, dietary supplemented with fermented QOR significantly increased the plasma contents of total protein (TP) and globulin (GLB) (P<0.05), and significantly decreased the ratio of albumin to GLB (ABL/GLB) (P<0.05) compared with the two control groups, as well as significantly increased plasma triglyceride content compared with the positive control group (P<0.05), while significantly decreased the plasma aspartic transaminase activity compared with the blank control group (P<0.05) and the plasma alkaline phosphatase activity compared with the QOR group and two control groups (P<0.05). At the 28th day of the experiment, dietary supplemented with QOR significantly increased the plasma contents of TP and total cholesterol (P<0.05), while significantly decreased ALB/GLB (P<0.05) compared with the positive control group, dietary supplemented with fermented QOR significantly decreased plasma high-density lipoprotein cholesterol content and superoxide dismutase (SOD) activity compared with the QOR group (P<0.05), and also significantly decreased the plasma glutathion peroxidase (GSH-Px) activity compared with the QOR group and blank control group (P<0.05). At the 28th day of the experiment, the plasma catalase activity in QOR group, contents of TP and GLB and GSH-Px activity in the fermented QOR group, and the plasma contents of TP, GLB and ALB in two control groups were significantly decreased (P<0.05), while the plasma SOD activity in the QOR group, ALB/GLB in the fermented QOR group and positive control group were significantly increased (P<0.05) compared with the 7th day of the experiment. Collectively, these findings suggest that dietary supplementated with the QOR can improve the immunity of weaned piglets, and dietary supplementated with the QOR or fermented QOR do not adversely affect the liver. Therefore, they can be used as feed additive in swine production.

Key words： Qi-Zha oral solution residues; fermentation; weaned piglets; biochemical parameters; antioxidant ability

参考文献

[1] 申俊华,周安国,王之盛,等.包被氧化锌对断奶仔猪腹泻指数及肠道发育的影响[J].畜牧兽医学报,2013,44(6):894-900.

[2] STARKE I C,PIEPER R,NEUMANN K,et al.The impact of high dietary zinc oxide on the development of the intestinal microbiota in weaned piglets[J].FEMS Microbiology Ecology,2014,87(2):416-427.  

[3] 刘秋东,张中文,刘凤华,等.复方白头翁胶囊对腹泻犬小肠绒毛长度和隐窝深度的影响[J].北京农学院学报,2011,26(3):38-40.

[4] 吕锦芳,闻爱友,宁康健,等.黄芩苷治疗仔猪腹泻的作用机制[J].中国兽医学报,2016,36(8):1401-1405.

[5] 丁月云,周芬,张巍,等.黄芪、红景天、当归对断奶仔猪生长性能及相关生理机能影响的比较[J].中国农业科学,2011,44(16):3469-3476.

[6] 孔祥峰,印遇龙,黄瑞林,等.中药超微粉饲料添加剂对断奶仔猪生长性能和血清生化参数的影响[J].中国兽医学报,2008,28(2):184-188.

[7] 苏家宜,姬玉娇,张婷,等.发酵中药渣对断奶仔猪血浆生化参数和抗氧化指标的影响[J].天然产物研究与开发,2017,29(2):284-289.

[8] 任建波,胡忠宏,赵洪波,等.不同形式氧化锌对断奶仔猪生长性能及腹泻的影响[J].中国畜牧兽医,2013,40(6):125-128.

[9] 苏家宜,孔祥峰,李华伟,等.芪楂口服液药渣对断奶仔猪生长性能和肠道健康的影响[J].动物营养学报,2017,29(5):1730-1738.

[10] 刘辉,季海峰,张董燕,等.饲粮添加短乳杆菌对生长猪生长性能和血清生化指标的影响[J].动物营养学报,2013,25(1):182-189.

[11] MORRILL J L,MORRILL J M,FEYERHERM A M,et al.Plasma proteins and a probiotic as ingredients in milk replacer[J].Journal of Dairy Science,1995,78(4):902-907.  

[12] 李林,刘进辉.芪楂口服液中黄芪甲苷含量的测定[J].中兽医学杂志,2014(7):4-5.

[13] 谭兵兵,姬玉娇,丁浩,等.低聚木糖对断奶仔猪生长性能、腹泻率和血浆生化参数的影响[J].动物营养学报,2016,28(8):2556-2563.

[14] 常启发,白会新,石宝明,等.黄腐酸对生长猪生长性能、血清生化指标、血常规参数和免疫功能的影响[J].动物营养学报,2013,25(8):1836-1842.

[15] LV Y F,TANG C H,WANG X Q,et al.Effects of dietary supplementation with palygorskite on nutrient utilization in weaned piglets[J].Livestock Science,2015,174:82-86.

[16] LIU Y Y,KONG X F,JIANG G L,et al.Effects of dietary protein/energy ratio on growth performance,carcass trait,meat quality,and plasma metabolites in pigs of different genotypes[J].Journal of Animal Science and Biotechnology,2015,6(1):36.

[17] 李瑞,侯改凤,黄其永,等.德氏乳杆菌对哺乳仔猪生长性能、血清生化指标、免疫和抗氧化功能的影响[J].动物营养学报,2013,25(12):2943-2950.

[18] WANG K K,CUI H W,SUN J Y,et al.Effects of zinc on growth performance and biochemical parameters of piglets[J].Turkish Journal of Veterinary & Animal Sciences,2012,36(5):519-526.

[19] 汤继顺,吴金节,王希春,等.锌源和锌水平对断奶应激仔猪血清生化指标的影响[J].中国兽医学报,2007,27(6):927-930,934.

[20] CHEN Y Y,GONG X X,LI G D,et al.Effects of dietary alfalfa flavonoids extraction on growth performance,organ development and blood biochemical indexes of Yangzhou geese aged from 28 to 70 days[J].Animal Nutrition,2016,2(4):318-322.  

[21] MA S Q,MA M L,MU C L,et al.Comparisons of blood biochemical parameters,digestive enzyme activities and volatile fatty acid profile between Meishan and Yorkshire piglets[J].Animal Nutrition,2015,1(4):289-292.  

[22] CHEN Y B,HU J,LYU Q J,et al.The effects of Natucin C-Natucin P mixture on blood biochemical parameters,antioxidant activity and non-specific immune responses in tilapia (Oreochromis niloticus)[J].Fish & Shellfish Immunology,2016,55:367-373.

[23] 苏斌朝,王连生,王红,等.玉米干酒糟及其可溶物饲粮中添加共轭亚油酸或甜菜碱对肥育猪生长性能、血清生化指标及抗氧化功能的影响[J].动物营养学报,2012,24(9):1737-1744.

[24] 王彦华,程宁宁,郑爱荣,等.苜蓿草粉和苜蓿皂苷对肥育猪生长性能和抗氧化性能的影响[J].动物营养学报,2013,25(12):2981-2988.

[25] 王翠菊,王洪芳,陈辉,等.黄芪多糖对蛋鸡抗氧化性能和蛋品质的影响[J].动物营养学报,2011,23(2):280-284.

[26] 白东清,吴旋,郭永军,等.长期投喂黄芪多糖对黄颡鱼抗氧化及非特异性免疫指标的影响[J].动物营养学报,2011,23(9):1622-1630.
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