本研究旨在探讨饲粮中铜添加量对断奶至2月龄长毛兔生产性能、血清生化指标及血清中酶活性的影响。选用蒙阴细毛型长毛兔180只，随机分为6组，每组30只，试验兔单笼饲养。6组试验兔分别饲喂在基础饲粮中添加0、10、20、40、80和160 mg/kg铜（添加形式为五水硫酸铜）的试验饲粮，试验饲粮中铜含量的实测值分别为3.25、13.13、23.40、43.56、83.58及163.87 mg/kg。预试期为7 d，正试期为23 d。结果表明：饲粮中铜添加量对长毛兔平均日增重（ADG）、料重比（F/G）的影响极显著（P<0.01），当铜添加量为80 mg/kg时，ADG最高，F/G最低。饲粮中铜添加量对长毛兔胎毛产量、毛直径及皮张面积的影响不显著（P>0.05）。饲粮中铜添加量对长毛兔血清中总蛋白（TP）、白蛋白（ALB）、球蛋白（GLB）、尿素氮（UN）含量及白球比（A/G）均有显著影响（P<0.05）。血清中UN含量随饲粮中铜添加量的升高呈现先下降后升高的趋势，当铜的添加量为80 mg/kg时，血清中UN的含量最低。饲粮中铜添加量对长毛兔血清中铜锌超氧化物歧化酶（Cu-Zn SOD）活性的影响不显著（P>0.05），但对血清中铜蓝蛋白（CP）活性的影响显著（P<0.05）。随着饲粮中铜添加量的升高，血清中铜蓝蛋白活性先升高后降低，在铜添加量为80 mg/kg时有最高值。饲粮中铜添加量对长毛兔肝脏指数有显著影响（P<0.05），而对其他内脏器官指数无显著影响（P>0.05）。当铜添加量为20 mg/kg时，肝脏指数最高。综合本试验测定指标，推荐断奶至2月龄长毛兔饲粮适宜的铜添加量为20~80 mg/kg。

This experiment was conducted to study the effects of dietary copper addition on performance, serum biochemical indices and serum enzymatic activities of weaning to 2-month-old long hairy rabbits. One hundred and eighty weaning Mengyin fine wool type long hairy rabbits were randomly assigned to 6 groups with 30 rabbits in each group, and the rabbits were feed separately. Rabbits in 6 groups were fed experimental diets which supplemented with 0, 10, 20, 40, 80 and 160 mg/kg copper (the form was CuSO₄·5H₂O) based on a basal diet, and the measured values of the copper in them were 3.25, 13.13, 23.40, 43.56, 83.58 and 163.87 mg/kg, respectively. The trail lasted for 7 days for adaption, and 23 days for test. The results showed as follows:dietary copper addition had extremely significant effects on average daily gain (ADG) and feed/gain (F/G) (P<0.01), and the highest value of ADG and lowest value of F/G were found when copper addition was 80 mg/kg. Dietary copper addition had no significant effects on lanugo production, wool diameter and fur area (P>0.05). Dietary copper addition had significant effects on the contents of total protein (TP), albumin (ALB), globulin (GLB) and urea nitrogen (UN), albumin/globulin (A/G) in serum (P<0.05). The serum UN content was firstly decreased and then increased with dietary copper addition increasing, and its lowest value was found when copper addition was 80 mg/kg. Dietary copper addition had no significant effect on serum copper-zinc superoxide dismutase (Cu-Zn SOD) activity (P>0.05), but it had significant effect on serum ceruloplasmin activity (P<0.05). The serum ceruloplasmin activity was firstly increased and then decreased with dietary copper addition increasing, and its highest value was found when copper addition was 80 mg/kg. Dietary copper addition had significant effect on liver index (P<0.05), but it had no significant effects on other organ indices (P>0.05). When copper addition was 80 mg/kg, the liver index had the highest value. Considering all indices of this experiment, the appropriate copper addition is 20 to 80 mg/kg for weaning to 2-month-old long hairy rabbits.