本试验旨在探究地鳖肽对氢化可的松诱导的氧化应激肉仔鸡生长性能、肉品质、脏器指数和抗氧化能力的影响。选用180只1日龄健康爱拔益加（AA）肉仔鸡，随机分为5组，分别为对照组、模型组（25 mg/L氢化可的松）和3个地鳖肽组［0.4、0.8和1.6 g/kg BW，每组6个重复，每个重复6只鸡。从第4天开始，3个地鳖肽组在饮水中加地鳖肽至第21天；从第8天开始，除对照组外，其余各组均在饮水中加氢化可的松，连续5 d。试验期21 d。结果表明：1）14日龄时，模型组肉仔鸡的血清皮质酮含量显著高于对照组和地鳖肽组（P<0.05）。2）1~14日龄时，与对照组相比，模型组肉仔鸡的平均日增重（ADG）显著降低（P<0.05），料重比（F/G）显著增加（P<0.05）；与模型组相比，地鳖肽组的F/G显著降低（P<0.05）。15~21日龄时，模型组的ADG和平均日采食量（ADFI）显著低于对照组（P<0.05）。1~21日龄时，模型组的ADG和ADFI显著低于对照组（P<0.05），F/G显著高于对照组（P<0.05）；与模型组相比，0.4和1.6 g/kg BW地鳖肽组的F/G显著降低（P<0.05）。3）14日龄时，与对照组相比，模型组肉仔鸡的胸肌pH_{45 min}和红度（a^*）值显著降低（P<0.05），胸肌、腿肌滴水损失显著升高（P<0.05）；与模型组相比，0.8 g/kg BW地鳖肽组的胸肌pH_{45 min}显著升高（P<0.05），胸肌滴水损失显著降低（P<0.05），0.4和1.6 g/kg BW地鳖肽组的腿肌滴水损失显著降低（P<0.05）。21日龄时，与模型组相比，0.4 g/kg BW地鳖肽组的胸肌a^*值显著升高（P<0.05），胸肌滴水损失显著降低（P<0.05）。4）14日龄时，模型组肉仔鸡的脾脏、胸腺和法氏囊指数显著低于对照组（P<0.05）；21日龄时，模型组的法氏囊指数显著低于对照组和1.6 g/kg BW地鳖肽组（P<0.05）。5）14日龄时，模型组肉仔鸡的肝脏和胸肌超氧化物歧化酶（SOD）活性显著低于对照组（P<0.05），肝脏和胸肌谷胱甘肽过氧化物酶（GSH-Px）活性显著低于对照组和0.4 g/kg BW地鳖肽组（P<0.05），肝脏和胸肌过氧化氢酶（CAT）活性显著低于对照组和0.8和1.6 g/kg BW地鳖肽组（P<0.05）。14和21日龄时，模型组的肝脏和胸肌丙二醛（MDA）含量显著高于对照组（P<0.05）。以上结果提示，地鳖肽可有效缓解氧化应激状态下肉仔鸡的应激反应，促进肉仔鸡生长，改善肉品质，提高机体抗氧化能力。

This experiment was conducted to investigate the effects of Eupolyphaga sinensis Walker polypeptides (ESWPs) on growth performance, meat quality, organ indexes and antioxidant capacity of broilers under oxidative stress induced by hydrocortisone. One hundred and eighty 1-day-old healthy Arbor Acres (AA) broilers were randomly divided into 5 groups with 6 replicates per group and 6 broilers per replicate. Five groups were control group, model group (25 mg/L hydrocortisone), and 0.4, 0.8 and 1.6 g/kg BW ESWPs groups, respectively. ESWPs were supplemented into the drinking water from the 4^th day to the 21^st day in the three ESWPs groups. At the 8^th day, hydrocortisone were supplemented into the drinking water in all groups except control group for 5 days. The experiment lasted for 21 days. The results showed as follows:1) serum corticosterone content of broilers in model group was significantly higher than that in control group and ESWPs groups at 14 days of age (P<0.05). 2) From 1 to 14 days of age, compared with control group, average daily gain (ADG) of broilers in model group was significantly decreased (P<0.05), and the ratio of feed to gain (F/G) significantly increased (P<0.05); compared with model group, F/G in ESWPs groups significantly decreased (P<0.05). From 15 to 21 days of age, ADG and average daily feed intake (ADFI) in model group were significantly lower than those in control group (P<0.05). From 1 to 21 days of age, ADG and ADFI in model group were significantly lower than those in control group (P<0.05), F/G in model group was significantly higher than that in control group (P<0.05); and F/G in 0.4 and 1.6 g/kg BW ESWPs groups was significantly lower than that in model group (P<0.05). 3) At 14 days of age, compared with control group, pH_{45 min} and redness (a^*) value in breast muscle of broilers in model group significantly decreased (P<0.05), and drip loss in breast and leg muscles significantly increased (P<0.05); compared with model group, pH_{45 min} in breast muscle in 0.8 g/kg BW ESWPs group significantly increased (P<0.05), drip loss in breast muscle was significantly decreased (P<0.05), and drip loss in leg muscle in 0.4 and 1.6 g/kg BW ESWPs groups was significantly decreased (P<0.05). At 21 days of age, compared with model group, the a^* value in breast muscle in 0.4 g/kg BW ESWPs group significantly increased (P<0.05), drip loss in breast muscle significantly decreased (P<0.05). 4) At 14 days of age, the indexes of spleen, thymus and bursa of Fabricius in model group were significantly lower than that in control group (P<0.05). At 21 days of age, bursa of Fabricius index in model group was significantly lower than that in control group and 1.6 g/kg BW ESWPs group (P<0.05). 5) At 14 days of age, the activity of superoxide dismutase (SOD) in liver and breast muscle of broilers in model group was significantly lower than that in control group (P<0.05), the activity of glutathione peroxidase (GSH-Px) in liver and breast muscle was significantly lower than that in control group and 0.4 g/kg BW ESWPs group (P<0.05), and the activity of catalase (CAT) in liver and breast muscle was significantly lower than that in control group and 0.8 and 1.6 g/kg BW ESWPs groups (P<0.05). At 14 and 21 days of age, the content of malondialdehyde (MDA) in liver and breast muscle in model group was significantly higher than that in control group (P<0.05). The results indicate that ESWPs can effectively alleviate the stress response of broilers under oxidative stress, promote broilers growth, improve meat quality, and enhance the antioxidant capacity of broilers.