[1] HANGAUER M J,VAUGHN I W,MCMANUS M T.Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs[J].PLoS Genetics,2013,9(6):e1003569.
[2] PONTING C P,OLIVER P L,REIK W.Evolution and functions of long noncoding RNAs[J].Cell,2009,136(4):629-641.

[3] STRUHL K.Transcriptional noise and the fidelity of initiation by RNA polymerase Ⅱ[J].Nature Structural & Molecular Biology,2007,14(2):103-105.

[4] KOERNER M V,PAULER F M,HUANG R,et al.The function of non-coding RNAs in genomic imprinting[J].Development,2009,136(11):1771-1783.

[5] RINN J L,CHANG H Y.Genome regulation by long noncoding RNAs[J].Annual Review of Biochemistry,2012,81(1):145-166.

[6] FUKUZAWA R,HEATHCOTT R W,MORISON I M,et al.Imprinting,expression,and localisation of DLK1 in Wilms tumours[J].Journal of Clinical Pathology,2005,58(2):145-150.

[7] MILLIGAN L,ANTOINE E,BISBAL C,et al.H19 gene expression is up-regulated exclusively by stabilization of the RNA during muscle cell differentiation[J].Oncogene,2000,19(50):5810-5816.

[8] OUNZAIN S,MICHELETTI R,ARNAN C,et al.CARMEN,a human super enhancer-associated long noncoding RNA controlling cardiac specification,differentiation and homeostasis[J].Journal of Molecular and Cellular Cardiology,2015,89:98-112.
[9] VAKOC C,HENIKOFF S,ARMSTRONG S.Chromatin deregulation in cancer[M].[S.l.]:[s.n.],2016.
[10] CHANG C P,HAN P.Epigenetic and lncRNA regulation of cardiac pathophysiology[J].Biochimica et Biophysica Acta:Molecular Cell Research,2016,1863(7):1767-1771.

[11] ZHANG X,SHA M L,YAO Y T,et al.Increased B-type-natriuretic peptide promotes myocardial cell apoptosis via the B-type-natriuretic peptide/long non-coding RNA LSINCT5/caspase-1/interleukin 1β signaling pathway[J].Molecular Medicine Reports,2015,12(5):6761-6767.

[12] ZHAO J J,ZHANG W,LIN M Y,et al.
MYOSLID is a novel serum response factor-dependent long noncoding RNA that amplifies the vascular smooth muscle differentiation program[J].Arteriosclerosis,Thrombosis,and Vascular Biology,2016,36(10):2088-2099.

[13] GORE-PANTER S R,HSU J,BARNARD J,et al.PANCR,the PITX2 adjacent noncoding RNA,is expressed in human left atria and regulates PITX2c expression[J].Circulation.Arrhythmia and Electrophysiology,2016,9(1):e003197.
[14] LI P,RUAN X B,YANG L,et al.A liver-enriched long non-coding RNA,lncLSTR,regulates systemic lipid metabolism in mice[J].Cell Metabolism,2015,21(3):455-467.

[15] ZHAO X Y,LI S M,WANG G X,et al.A long noncoding RNA transcriptional regulatory circuit drives thermogenic adipocyte differentiation[J].Molecular Cell,2014,55(3):372-382.

[16] PANZITT K,TSCHERNATSCH M M O,GUELLY C,et al.Characterization of
HULC,a novel gene with striking up-regulation in hepatocellular carcinoma,as noncoding RNA[J].Gastroenterology,2007,132(1):330-342.

[17] SUN L,GOFF L A,TRAPNELL C,et al.Long noncoding RNAs regulate adipogenesis[J].Proceedings of the National Academy of Sciences of the United States of America,2013,110(9):3387-3392.

[18] XU B,GERIN I,MIAO H Z,et al.Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity[J].PLoS One,2010,5(12):e14199.
[19] GONG C G,LI Z Z,RAMANUJAN K,et al.A long non-coding RNA,LncMyoD,regulates skeletal muscle differentiation by blocking IMP2-mediated mRNA translation[J].Developmental Cell,2015,34(2):181-191.

[20] ZHU L,XU P C.Downregulated LncRNA-ANCR promotes osteoblast differentiation by targeting
EZH2 and regulating
Runx2 expression[J].Biochemical and Biophysical Research Communications,2013,432(4):612-617.

[21] HAIJUN Z,YONGHUI Y,JIAKE C.Expression signatures of lncRNAs in skeletal muscles at the early flow phase revealed by microarray in burned rats[J].Ulusal Travma ve Acil Cerrahi Dergisi,2016,22(3):224-232.
[22] MUELLER A C,CICHEWICZ M A,DEY B K,et al.MUNC,a long noncoding RNA that facilitates the function of MyoD in skeletal myogenesis[J].Molecular and Cellular Biology,2015,35(3):498-513.

[23] BASILE V,BARUFFALDI F,DOLFINI D,et al.NF-YA splice variants have different roles on muscle differentiation[J].Biochimica et Biophysica Acta:Gene Regulatory Mechanisms,2016,1859(4):627-638.

[24] WANG G Q,WANG Y,XIONG Y,et al.
Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a[J].Scientific Reports,2016,6:21865.
[25] LANZ R B,MCKENNA N J,ONATE S A,et al.A steroid receptor coactivator,SRA,functions as an RNA and is present in an SRC-1 complex[J].Cell,1999,97(1):17-27.

[26] LIU S,XU R C,GERIN I,et al.SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling[J].PLoS One,2014,9(4):e95416.
[27] LIU S,SHENG L,MIAO H Z,et al.SRA gene knockout protects against diet-induced obesity and improves glucose tolerance[J].Journal of Biological Chemistry,2014,289(19):13000-13009.

[28] CHEN G,YU D S,NIAN X,et al.LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (
ATGL)[J].Scientific Reports,2016,6:35531.
[29] HUANG H J,TINDALL D J.Regulation of FOXO protein stability via ubiquitination and proteasome degradation[J].Biochimica et Biophysica Acta (BBA):Molecular Cell Research,2011,1813(11):1961-1964.

[30] LIU J Y,YAO J,LI X M,et al.Pathogenic role of lncRNA-MALAT1 in endothelial cell dysfunction in diabetes mellitus[J].Cell Death & Disease,2014,5(10):e1506.
[31] YAN B,TAO Z F,LI X M,et al.Aberrant expression of long noncoding RNAs in early diabetic retinopathy[J].Investigative Opthalmology & Visual Science,2014,55(2):941-951.

[32] WATTS R,GHOZLAN M,HUGHEY C C,et al.Myostatin inhibits proliferation and insulin-stimulated glucose uptake in mouse liver cells[J].Biochemistry and Cell Biology,2014,92(3):226-234.

[33] YAN C F,CHEN J F,CHEN N Q.Long noncoding RNA MALAT1 promotes hepatic steatosis and insulin resistance by increasing nuclear SREBP-1c protein stability[J].Scientific Reports,2016,6:22640.
[34] BIDDINGER S B,ALMIND K,MIYAZAKI M,et al.Effects of diet and genetic background on sterol regulatory element-binding protein-1c,stearoyl-CoA desaturase 1,and the development of the metabolic syndrome[J].Diabetes,2005,54(5):1314-1323.

[35] WANG F,TONG Q.Transcription factor PU.1 is expressed in white adipose and inhibits adipocyte differentiation[J].American Journal of Physiology:Cell Physiology,2008,295(1):C213-C220.
[36] EBRALIDZE A K,GUIBAL F C,STEIDL U,et al.
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element[J].Genes & Development,2008,22(15):2085-2092.

[37] PANG W J,LIN L G,XIONG Y,et al.Knockdown of PU.1 AS lncRNA inhibits adipogenesis through enhancing
PU.1 mRNA translation[J].Journal of Cellular Biochemistry,2013,114(11):2500-2512.

[38] WEI N,WANG Y,XU R X,et al.
PU.1 antisense lncRNA against its mRNA translation promotes adipogenesis in porcine preadipocytes[J].Animal Genetics,2015,46(2):133-140.

[39] 荣灿,崔县伟,相俐至,等.长链非编码RNA uc.417的生物信息学分析及其在棕色脂肪细胞中的表达研究[J].中华糖尿病杂志,2015,7(4):257-262.
[40] VAN MARKEN LICHTENBELT W D,VANHOMMERIG J W,SMULDERS N M,et al.Cold-activated brown adipose tissue in healthy men[J].The New England Journal of Medicine,2009,360(15):1500-1508.

[41] CUI X,YOU L,LI Y,et al.A transcribed ultraconserved noncoding RNA,uc.417,serves as a negative regulator of brown adipose tissue thermogenesis[J].FASEB Journal,2016,30(12):4301-4312.

[42] LIU W H,MA C L,YANG B,et al.LncRNA Gm15290 sponges miR-27b to promote PPARγ-induced fat deposition and contribute to body weight gain in mice[J].Biochemical and Biophysical Research Communications,2017,493(3):1168-1175.

[43] DIVOUX A,KARASTERGIOU K,XIE H,et al.Identification of a novel lncRNA in gluteal adipose tissue and evidence for its positive effect on preadipocyte differentiation[J].Obesity,2014,22(8):1781-1785.

[44] LI M X,SUN X M,CAI H F,et al.Long non-coding RNA ADNCR suppresses adipogenic differentiation by targeting miR-204[J].Biochimica et Biophysica Acta:Gene Regulatory Mechanisms,2016,1859(7):871-882.

[45] CHEN J,LIU Y,LU S,et al.The role and possible mechanism of lncRNA U90926 in modulating 3T3-L1 preadipocyte differentiation[J].International Journal of Obesity,2016,41(2):299-308.
[46] YANG Y R,JANG H J,CHOI S S,et al.Obesity resistance and increased energy expenditure by white adipose tissue browning in
Oga+/- mice[J].Diabetologia,2015,58(12):2867-2876.

[47] SUÁREZ-ZAMORANO N,FABBIANO S,CHEVALIER C,et al.Microbiota depletion promotes browning of white adipose tissue and reduces obesity[J].Nature Medicine,2015,21(12):1497-1501.

[48] TRAN C M,MUKHERJEE S,YE L,et al.Rapamycin blocks induction of the thermogenic program in white adipose tissue[J].Diabetes,2016,65(4):927-941.

[49] YOU L H,ZHOU Y H,CUI X W,et al.GM13133 is a negative regulator in mouse white adipocytes differentiation and drives the characteristics of brown adipocytes[J].Journal of Cellular Physiology,2018,233(1):313-324.

[50] YE L,WU J,COHEN P,et al.Fat cells directly sense temperature to activate thermogenesis[J].Proceedings of the National Academy of Sciences of the United States of America,2013,110(30):12480-12485.