综述 Review

宿主防御肽在奶牛乳腺中的表达及应用

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  • 黑龙江八一农垦大学动物科技学院, 大庆 163319
王可鑫(1995-),女,黑龙江鹤岗人,硕士研究生,研究方向为动物营养与饲料科学。E-mail:1677572962@qq.com

收稿日期: 2018-10-31

  网络出版日期: 2019-05-15

基金资助

国家自然科学基金项目(31472120);黑龙江省农垦总局十三五重点研发项目(HNK135-04-03);黑龙江省科技厅中央引导地方项目(ZY17C08);黑龙江省自然科学基金项目(JJ2019LH0397)

Expression and Applications of Host Defense Peptides in Cow Mammary Gland

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  • College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing 163319, China

Received date: 2018-10-31

  Online published: 2019-05-15

摘要

宿主防御肽是生物体内产生的一类具有抗菌作用的阳离子多肽,是生物体非特异性免疫功能的重要组成部分。宿主防御肽具有广谱、抗菌、耐热、无毒、不易产生耐药性等诸多特性,在畜牧生产中具有广阔的应用前景。本文主要对宿主防御肽在先天免疫系统中的作用、奶牛乳腺中的表达及乳房炎诊断与治疗应用的研究进展进行综述,为宿主防御肽作为抗生素替代品在畜牧生产中的研究与应用提供理论支持。

本文引用格式

王可鑫, 王鑫, 姜宁, 张爱忠 . 宿主防御肽在奶牛乳腺中的表达及应用[J]. 动物营养学报, 2019 , 31(5) : 2038 -2044 . DOI: 10.3969/j.issn.1006-267x.2019.05.009

Abstract

Host defense peptides are a kind of antibacterial cationic peptides, which are produced in living organisms. They are important parts of the nonspecific immune function of organisms. As their characteristics of broad spectrum, antibacterial, heat resistance, no residue, and non-drug resistance, host defense peptides have broad application prospects in livestock production. Overall, the role of host defense peptides in the innate immune system, the expression in the mammary gland of cows and the research progress in application of diagnosis and treatment of mastitis were reviewed in this paper, which would provide a theoretical basis for the further research and application of host defense peptides in livestock production.

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