综述 Review

尿苷酸的营养代谢与生理功能研究进展

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  • 1. 湖南农业大学动物科学技术学院, 湖南省畜禽安全生产协同创新中心, 长沙 410128;
    2. 中国科学院亚热带农业生态研究所, 亚热带农业生态过程重点实验室, 湖南省畜禽健康养殖工程技术中心, 农业部中南动物营养与饲料科学观测实验站, 畜禽养殖污染控制与资源化技术国家工程实验室, 长沙 410125
李彪(1982-),男,四川大竹人,博士研究生,研究方向为动物营养和生理。E-mail:12942508@qq.com

收稿日期: 2018-11-21

  网络出版日期: 2019-06-17

基金资助

国家重点研发计划项目(2016YFD0500504);中国科学院STS项目;湖南农业科技创新资金项目(2018ZD12)

Research Progresses on Nutrition Metabolism and Physiological Function of Uridine Monophosphate

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  • 1. Hunan Co-Innovation Center of Safety Animal Production, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China;
    2. Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Changsha 410125, China

Received date: 2018-11-21

  Online published: 2019-06-17

摘要

在猪乳的5种核苷酸(尿苷酸、胞苷酸、肌苷酸、鸟苷酸以及腺苷酸)中,尿苷酸的含量最为丰富,占乳汁中总核苷酸的90%以上。与母猪乳汁相比,仔猪教槽料中尿苷酸最为缺乏,这种现象在仔猪断奶早期尤其明显,因此,尿苷酸可能对仔猪正常的生长发育起着重要的作用。尿苷酸作为一种基础的嘧啶核苷酸类化合物,具有非常重要的生理功能。本文从尿苷酸的结构、吸收代谢、生理功能、与三大营养物质代谢关系及在动物生产中的潜在应用等方面予以综述,旨在为单核苷酸在动物生产中的添加和单核苷酸营养提供参考。

本文引用格式

李彪, 吴信, 张彬, 印遇龙 . 尿苷酸的营养代谢与生理功能研究进展[J]. 动物营养学报, 2019 , 31(6) : 2487 -2494 . DOI: 10.3969/j.issn.1006-267x.2019.06.006

Abstract

Uridine monophosphate is the most abundant nucleotide among the five nucleotides (uridine monophosphate, cytidine monophosphate, inosine monophosphate, guanosine monophosphate and adenosine monophosphate) in sow's milk, and it is more than 90% of total nucleotides in sow's milk. Compared with the sow's milk, the content of uridine monophosphate in creep feeds is the most lacking, and this phenomenon is evident especially in the early weaning stage. Therefore, uridine monophosphate may play important roles in the normal growth and development of piglets. As a basic pyrimidine nucleotide compound, uridine monophosphate has very important physiological functions. This paper reviews the structure, absorption and metabolism, biological functions, metabolism relationship with three major nutrients and potential application in animal production and so on, aims to providing reference for single nucleotide supplementation to diets for animals and single nucleotide nutrition.

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