[1] CANANI R B,DI COSTANZO M,LEONE L,et al.Epigenetic mechanisms elicited by nutrition in early life[J].Nutrition Research Reviews,2011,24(2):198-205.
[2] SIKANDAR A,ZANEB H,YOUNUS M,et al.Effect of sodium butyrate on performance,immune status,microarchitecture of small intestinal mucosa and lymphoid organs in broiler chickens[J].Asian-Australasian Journal of Animal Sciences,2017,30(5):690-699.
[3] XIA S,YAO W,ZOU B,et al.Effects of potassium diformate on the gastric function of weaning piglets[J].Animal Production Science,2016,56(7):1161-1166.
[4] 李丹丹,冯国强,钮海华,等.丁酸钠对断奶仔猪生长性能及免疫功能的影响[J].动物营养学报,2012,24(2):307-313.
[5] TOPPING D L,CLIFTON P M.Short-chain fatty acids and human colonic function:roles of resistant starch and nonstarch polysaccharides[J].Physiological Reviews,2001,81(3):1031-1064.
[6] KUMAR A,ALREFAI W A,BORTHAKUR A,et al.Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells[J].American Journal of Physiology:Gastrointestinal and Liver Physiology,2015,309(7):G602-G607.
[7] TAN J,MCKENZIE C,POTAMITIS M,et al.The role of short-chain fatty acids in health and disease[J].Advances in Immunology,2014,121:91-119.
[8] ROBERFROID M B.Introducing inulin-type fructans[J].British Journal of Nutrition,2005,93(S1):S13-S25.
[9] MACFARLANE S,MACFARLANE G T.Regulation of short-chain fatty acid production[J].The Proceedings of the Nutrition Society,2003,62(1):67-72.
[10] LATTIMER J M,HAUB M D.Effects of dietary fiber and its components on metabolic health[J].Nutrients,2010,2(12):1266-1289.
[11] MARTIN L J M,DUMON H J W,CHAMP M M J.Production of short-chain fatty acids from resistant starch in a pig model[J].Journal of the Science of Food and Agriculture,1998,77(1):71-80.
[12] ROY C C,KIEN C L,BOUTHILLIER L,et al.Short-chain fatty acids:ready for prime time?[J].Nutrition in Clinical Practice,2006,21(4):351-366.
[13] LOUIS P,HOLD G L,FLINT H J.The gut microbiota,bacterial metabolites and colorectal cancer[J].Nature Reviews Microbiology,2014,12(10):661-672.
[14] TAZOE H,OTOMO Y,KAJI I,et al.Roles of short-chain fatty acids receptors,GPR41 and GPR43 on colonic functions[J].Journal of Physiology and Pharmacology,2008,59 Suppl.2:251-262.
[15] FAN P X,LI L S,REZAEI A,et al.Metabolites of dietary protein and peptides by intestinal microbes and their impacts on gut[J].Current Protein & Peptide Science,2015,16(7):646-654.
[16] VITAL M,HOWE A C,TIEDJE J M.Revealing the bacterial butyrate synthesis pathways by analyzing (Meta)genomic data[J].MBio,2014,5(2):e00889-14.
[17] KOH A,DE VADDER F,KOVATCHEVA-DATCHARY P,et al.From dietary fiber to host physiology:short-chain fatty acids as key bacterial metabolites[J].Cell,2016,165(6):1332-1345.
[18] RIOS-COVIAN D,SALAZAR N,GUEIMONDE M,et al.Shaping the metabolism of intestinal Bacteroides population through diet to improve human health[J].Frontiers in Microbiology,2017,8:376.
[19] DEN BESTEN G,LANGE K,HAVINGA R,et al.Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids[J].American Journal of Physiology:Gastrointestinal and Liver Physiology,2013,305(12):G900-G910.
[20] REY F E,FAITH J J,BAIN J,et al.Dissecting the in vivo metabolic potential of two human gut acetogens[J].The Journal of Biological Chemistry,2010,285(29):22082-22090.
[21] RAGSDALE S W,PIERCE E.Acetogenesis and the Wood-Ijungdahl pathway of CO
2 fixation[J].Biochimica et Biophysica Acta:Proteins and Proteomics,2008,1784(12):1873-1898.
[22] SCOTT K P,MARTIN J C,CAMPBELL G,et al.Whole-genome transcription profiling reveals genes up-regulated by growth on fucose in the human gut bacterium "Roseburia inulinivorans"[J].Journal of Bacteriology,2006,188(12):4340-4349.
[23] HOSSEINI E,GROOTAERT C,VERSTRAETE W,et al.Propionate as a health-promoting microbial metabolite in the human gut[J].Nutrition Reviews,2011,69(5):245-258.
[24] DUNCAN S H,BARCENILLA A,STEWART C S,et al.Acetate utilization and butyryl coenzyme A (CoA):acetate-CoA transferase in butyrate-producing bacteria from the human large intestine[J].Applied and Environmental Microbiology,2002,68(10):5186-5190.
[25] CUMMINGS J H,BINGHAM S A,HEATON K W,et al.Fecal weight,colon cancer risk,and dietary intake of nonstarch polysaccharides (dietary fiber)[J].Gastroenterology,1992,103(6):1783-1789.
[26] MACFARLANE S,QUIGLEY M E,HOPKINS M J,et al.Polysaccharide degradation by human intestinal bacteria during growth under multi-ubstrate limiting conditions in a three-tage continuous culture system[J].FEMS Microbiology Ecology,1998,26(3):231-243.
[27] BYRNE C S,CHAMBERS E S,MORRISON D J,et al.The role of short chain fatty acids in appetite regulation and energy homeostasis[J].International Journal of Obesity,2015,39(9):1331-1338.
[28] KIM M,QIE Y Q,PARK J,et al.Gut microbial metabolites fuel host antibody responses[J].Cell Host & Microbe,2016,20(2):202-214.
[29] RICHARDS J L,YAP Y A,MCLEOD K H,et al.Dietary metabolites and the gut microbiota:an alternative approach to control inflammatory and autoimmune diseases[J].Clinical & Translational Immunology,2016,5(5):e82.
[30] CHANG P V,HAO L M,OFFERMANNS S,et al.The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition[J].Proceedings of the National Academy of Sciences of the United States of America,2014,111(6):2247-2252.
[31] LE POUL E,LOISON C,STRUYF S,et al.Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation[J].Journal of Biological Chemistry,2003,278(28):25481-25489.
[32] MASLOWSKI K M,VIEIRA A T,NG A,et al.Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43[J].Nature,2009,461(7268):1282-1286.
[33] ARPAIA N,CAMPBELL C,FAN X Y,et al.Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation[J].Nature,2013,504(7480):451-455.
[34] FURUSAWA Y,OBATA Y,FUKUDA S,et al.Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells[J].Nature,2013,504(7480):446-450.
[35] THANGARAJU M,CRESCI G A,LIU K B,et al.GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon[J].Cancer Research,2009,69(7):2826-2832.
[36] SINGH N,GURAV A,SIVAPRAKASAM S,et al.Activation of GPR109A,receptor for niacin and the commensal metabolite butyrate,suppresses colonic inflammation and carcinogenesis[J].Immunity,2014,40(1):128-139.
[37] KIM H J,BAE S C.Histone deacetylase inhibitors:molecular mechanisms of action and clinical trials as anti-cancer drugs[J].American Journal of Translational Research,2011,3(2):166-179.
[38] FLINT H J,SCOTT K P,LOUIS P,et al.The role of the gut microbiota in nutrition and health[J].Nature Reviews Gastroenterology & Hepatology,2012,9(10):577-589.
[39] DAVIE J R.Inhibition of histone deacetylase activity by butyrate[J].Journal of Nutrition,2003,133(7 Suppl):2485S-2493S.
[40] LIU H,WANG J,HE T,et al.Butyrate:a double-edged sword for health?[J].Advances in Nutrition,2018,9(1):21-29.
[41] SUN M M,WU W,LIU Z J,et al.Microbiota metabolite short chain fatty acids,GPCR,and inflammatory bowel diseases[J].Journal of Gastroenterology,2017,52(1):1-8.
[42] LIN M Y,DE ZOETE M R,VAN PUTTEN J P M,et al.Redirection of epithelial immune responses by short-chain fatty acids through inhibition of histone deacetylases[J].Frontiers in Immunology,2015,6:554.
[43] VINOLO M A R,HATANAKA E,LAMBERTUCCI R H,et al.Effects of short chain fatty acids on effector mechanisms of neutrophils[J].Cell Biochemistry & Function,2009,27(1):48-55.
[44] GURAV A,SIVAPRAKASAM S,BHUTIA Y D,et al.SLC5A8,a Na
+-coupled high-affinity transporter for short-chain fatty acids,is a conditional tumor suppressor in colon that protects against colitis and colon cancer under low-fiber dietary conditions[J].The Biochemical Journal,2015,469(2):267-278.
[45] PARK J,KIM M,KANG S G,et al.Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway[J].Mucosal Immunology,2015,8(1):80-93.
[46] ISHIKAWA T,NANJO F.Dietary cycloinulooligosaccharides enhance intestinal immunoglobulin A production in mice[J].Bioscience,Biotechnology,and Biochemistry,2009,73(3):677-682.
[47] NEPELSKA M,DE WOUTERS T,JACOUTON E,et al.Commensal gut bacteria modulate phosphorylation-dependent PPARγ transcriptional activity in human intestinal epithelial cells[J].Scientific Reports,2017,7:43199.
[48] BYNDLOSS M X,OLSAN E E,RIVERA-CHÁVEZ F,et al.Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion[J].Science,2017,357(6351):570-575.
[49] MA X,FAN P X,LI L S,et al.Butyrate promotes the recovering of intestinal wound healing through its positive effect on the tight junctions[J].Journal of Animal Science,2012,90(Suppl.4):266-268.
[50] KIMURA I,INOUE D,MAEDA T,et al.Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41(GPR41)[J].Proceedings of the National Academy of Sciences of the United States of America,2011,108(19):8030-8035.
[51] TONG L C,WANG Y,WANG Z B,et al.Propionate ameliorates dextran sodium sulfate-induced colitis by improving intestinal barrier function and reducing inflammation and oxidative stress[J].Frontiers in Pharmacology,2016,7:253.
[52] PENG L Y,LI Z R,GREEN R S,et al.Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers[J].The Journal of Nutrition,2009,139(9):1619-1625.
[53] HUANG C,SONG P X,FAN P X,et al.Dietary sodium butyrate decreases postweaning diarrhea by modulating intestinal permeability and changing the bacterial communities in weaned piglets[J].The Journal of Nutrition,2015,145(12):2774-2780.
[54] MARCIL V,DELVIN E,SEIDMAN E,et al.Modulation of lipid synthesis,apolipoprotein biogenesis,and lipoprotein assembly by butyrate[J].American Journal Physiology:Gastrointestinal and Liver Physiology,2002,283(2):G340-G346.
[55] SHEN H,LU Z Y,XU Z H,et al.Associations among dietary non-fiber carbohydrate,ruminal microbiota and epithelium G-protein-coupled receptor,and histone deacetylase regulations in goats[J].Microbiome,2017,5(1):123.
[56] KUNZELMANN K,MALL M.Electrolyte transport in the mammalian colon:mechanisms and implications for disease[J].Physiological Reviews,2002,82(1):245-289.
[57] RABBANI G H,ALBERT M J,RAHMAN H,et al.Short-chain fatty acids inhibit fluid and electrolyte loss induced by cholera toxin in proximal colon of rabbit in vivo[J].Digestive Diseases and Sciences,1999,44(8):1547-1553.
[58] BINDER H J,MEHTA P.Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon[J].Gastroenterology,1989,96(4):989-996.
[59] VIDYASAGAR S,RAMAKRISHNA B S.Effects of butyrate on active sodium and chloride transport in rat and rabbit distal colon[J].Journal of Physiology,2010,539(1):163-173.
[60] LIEM A,PESTI G M,EDWARDS H M,Jr.The effect of several organic acids on phytate phosphorus hydrolysis in broiler chicks[J].Poultry Science,2008,87(4):689-693.
[61] HUANG X Z,LI Z R,ZHU L B,et al.Inhibition of p38 mitogen-activated protein kinase attenuates butyrate-induced intestinal barrier impairment in a Caco-2 cell monolayer model[J].Journal of Pediatric Gastroenterology and Nutrition,2014,59(2):264-269.
[62] VAN IMMERSEEL F,FIEVEZ V,DE BUCK J,et al.Microencapsulated short-chain fatty acids in feed modify colonization and invasion early after infection with Salmonella enteritidis in young chickens[J].Poultry Science,2004,83(1):69-74.
[63] 郭传珍,曹兵海.丁酸钠对肉鸡肠道pH值、微生物菌群和挥发性脂肪酸的影响研究[J].中国家禽,2009,31(21):14-17,21.
[64] TROMPETTE A,GOLLWITZER E S,YADAVA K,et al.Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis[J].Nature Medicine,2014,20(2):159-166.
[65] CANI P D.Gut cell metabolism shapes the microbiome[J].Science,2017,357(6351):548-549.
[66] 寇莎莎,王诏升,徐德旺,等.日粮中添加不同水平丁酸钠对断奶仔猪生长性能、腹泻率及血液生化指标的影响[J].中国畜牧兽医,2018,45(7):1841-1848.
[67] 李虹瑾,沙万里,尹柏双,等.包膜丁酸钠对断奶仔猪肠道菌群及生长性能的影响[J].家畜生态学报,2017,38(9):30-34.
[68] 黄建华,李春莲,杨凤梅,等.二甲酸钾对断奶仔猪大肠杆菌和乳酸杆菌的影响[J].湖北农业科学,2013,52(1):124-126.
[69] 钟翔,黄小国,陈莎莎,等.丁酸钠对断奶仔猪生长性能和肠道消化酶活性的影响[J].动物营养学报,2009,21(5):719-726.
[70] RAGAA N M,KORANY R M S.Studying the effect of formic acid and potassium diformate on performance,immunity and gut health of broiler chickens[J].Animal Nutrition,2016,2(4):296-302.
[71] 张浩,董磊,王英俊,等.丁酸甘油酯对肉鸡生长性能、养分表观消化率、屠宰性能、肠道形态及微生物菌群的影响[J].中国畜牧兽医,2016,43(8):2013-2019.
[72] 赵民,徐小芳,余荣.包膜丁酸钠对青脚麻种鸡生产性能的影响[J].饲料工业,2012,33(20):33-34.
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