综述 Review

功能性氨基酸对母猪胎盘功能影响的研究进展

  • 唐燕妮 ,
  • 施魁 ,
  • 管武太 ,
  • 陈芳
展开
  • 华南农业大学动物科学学院, 广州 510642
唐燕妮(1997-),女,湖南邵阳人,硕士研究生,研究方向为动物营养与饲料科学。E-mail:844704684@qq.com

收稿日期: 2019-04-05

  网络出版日期: 2019-11-19

基金资助

国家重点研发计划资助(2018YFD0501000)

Research Progress on Effects of Functional Amino Acids on Placental Function of Sows

  • TANG Yanni ,
  • SHI Kui ,
  • GUAN Wutai ,
  • CHEN Fang
Expand
  • College of Animal Sciences, South China Agricultural University, Guangzhou 510642, China

Received date: 2019-04-05

  Online published: 2019-11-19

摘要

功能性氨基酸是指可以通过调节动物机体的关键代谢通路,对人和动物的生长发育、繁殖健康有促进作用,对生命活动起到诸多生理调控作用的氨基酸。一些功能性氨基酸及其产物对母猪胎盘功能有着重要的作用。胎盘是妊娠期间由胚胎胚膜和母体子宫内膜联合长成的母子间组织结合器官,具备物质交换、代谢、防御及激素合成等重要功能。在孕期,胎盘是胎儿和母体之间传递物质的枢纽,它可以从母体运输氧气、二氧化碳、水和一些其他的胎儿生长发育所必需的营养物质,也可以将胎儿的代谢废物等通过母体排出。本文从几个研究较多的功能性氨基酸(精氨酸、脯氨酸、谷氨酰胺和支链氨基酸)入手,分别就其对母猪胎盘功能的影响进行了综述,旨在促进功能性氨基酸在母猪生产中更好地开发利用。

本文引用格式

唐燕妮 , 施魁 , 管武太 , 陈芳 . 功能性氨基酸对母猪胎盘功能影响的研究进展[J]. 动物营养学报, 2019 , 31(11) : 4927 -4932 . DOI: 10.3969/j.issn.1006-267x.2019.11.004

Abstract

Functional amino acids refer to a kind of amino acid that can promote the growth and reproduction of humans and animals by regulating the key metabolic pathways of the animals, and exert many physiological regulation effects on life activities. Some functional amino acids and their products play an important role on the sow's placental function. The placenta is a joint organ between the sow and piglet that is formed by the combination of the embryonic germ membrane and the maternal endometrium during pregnancy. It has important functions such as exchange of material, metabolism, defense and synthetic hormone. During the pregnancy period, the placenta is the hub of the material transfer between the fetus and the matrix. It can transport oxygen, carbon dioxide, water and some other nutrients necessary for the growth and development of the fetus from the matrix, and it can also discharge the metabolic waste of fetal through the matrix. This paper studied several functional amino acids, such as arginine, proline, glutamine and branched-chain amino acids, and reviewed respectively the effects of them on sow placenta function, in order to promote the development and utilization of functional amino acids in sow production.

参考文献

[1] FOWDEN A L,FORHEAD A J,COAN P M,et al.The placenta and intrauterine programming[J].Journal of Neuroendocrinology,2008,20(4):439-450.  
[2] 胡健,姚姣姣,颜培实.母猪胎盘效率及胎盘中糖代谢相关基因的研究[C]//中国畜牧兽医学会2014年家畜环境卫生学分会学术年会论文集.武汉:中国畜牧兽医学会家畜环境卫生学分会,2014.
[3] DUAN Y H,LI F N,LI Y H,et al.The role of leucine and its metabolites in protein and energy metabolism[J].Amino Acids,2016,48(1):41-51.  
[4] 朱玉华,薛欣合,周天骄,等.谷氨酰胺、精氨酸和亮氨酸缺乏诱导猪肠道上皮细胞自噬的研究[C]//中国畜牧兽医学会动物营养学分会第十一次全国动物营养学术研讨会论文集.长沙:中国畜牧兽医学会动物营养学分会,2012.
[5] 聂新志,蒋宗勇,林映才,等.精氨酸和谷氨酰胺对猪小肠上皮细胞增殖的影响及机理探讨[J].中国农学通报,2012,28(2):1-5.
[6] 陈云平,吕春梅,朱辉.胎盘氨基酸转运体的研究进展[J].中国妇幼保健,2013,28(26):4416-4418.
[7] WU G Y,BAZER F W,HU J B,et al.Polyamine synthesis from proline in the developing porcine placenta[J].Biology of Reproduction,2005,72(4):842-850.  
[8] 符晨星.功能性氨基酸对猪上皮细胞蛋白周转及母猪繁殖性能的作用机制研究[D].博士学位论文.长沙:湖南农业大学,2015.
[9] 刘俊锋,吴琛,孔祥峰,等.精氨酸对妊娠环江香猪胎儿生长发育的影响[J].中国农业科学,2011,44(5):1040-1045.
[10] BAUMANN M U,DEBORDE S,ILLSLEY N P.Placental glucose transfer and fetal growth[J].Endocrine,2002,19(1):13-22.  
[11] 郭棚,朱翠,高开国,等.精氨酸对怀孕母猪胎盘滋养层细胞调控作用研究进展[J].东北农业大学学报,2017,48(3):89-96.
[12] JANSSON T.Amino acid transporters in the human placenta[J].Pediatric Research,2001,49(2):141-147.  
[13] 陈翠玲.日粮精氨酸在妊娠母猪中的应用[J].饲料博览,2012(7):20-23.
[14] MATEO R D,WU G Y,BAZER F W,et al.Dietary L-arginine supplementation enhances the reproductive performance of gilts[J].The Journal of Nutrition,2007,137(3):652-656.  
[15] BAZER F W,KIM J,KA H,et al.Select nutrients in the uterine lumen of sheep and pigs affect conceptus development[J].Journal of Reproduction and Development,2012,58(2):180-188.  
[16] 查伟.饲粮添加脯氨酸对环江香猪繁殖性能及其后代生长发育的影响[D].硕士学位论文.南昌:江西农业大学,2015.
[17] 晋超,吴德,方正峰,等.精氨酸对妊娠母猪繁殖性能的调节作用[J].动物营养学报,2010,22(6):1495-1500.
[18] ZENG X F,WANG F L,FAN X,et al.Dietary arginine supplementation during early pregnancy enhances embryonic survival in rats[J].The Journal of Nutrition,2008,138(8):1421-1425.  
[19] WU G Y,BAZER F W,DAVIS T A,et al.Important roles for the arginine family of amino acids in swine nutrition and production[J].Livestock Science,2007,112(1/2):8-22.
[20] 郭长义,蒋宗勇,林韬.精氨酸在猪营养中应用的研究进展[J].中国饲料,2009(8):31-36.
[21] WU G Y,BAZER F W,BURGHARDT R C,et al.Proline and hydroxyproline metabolism:implications for animal and human nutrition[J].Amino Acids,2011,40(4):1053-1063.  
[22] KWON H,FORD S P,BAZER F W,et al.Maternal nutrient restriction reduces concentrations of amino acids and polyamines in ovine maternal and fetal plasma and fetal fluids[J].Biology of Reproduction,2004,71(3):901-908.  
[23] 谢春艳,张宇喆,吴信,等.胎盘胎儿复合体谷氨酸-谷氨酰胺循环和交换的生理作用及其调控[J].动物营养学报,2014,26(6):1430-1434.
[24] WU G,BAZER F W,DATTA S,et al.Proline metabolism in the conceptus:implications for fetal growth and development[J].Amino Acids,2008,35(4):691-702.  
[25] HATANAKA T,HATANAKA Y,TSUCHIDA J I,et al.Amino acid transporter ATA2 is stored at the trans-Golgi network and released by insulin stimulus in adipocytes[J].Journal of Biological Chemistry,2006,281(51):39273-39284.  
[26] WU G,BAZER F W,BURGHARDT R C,et al.Impacts of amino acid nutrition on pregnancy outcome in pigs:mechanisms and implications for swine production[J].Journal of Animal Science,2010,88(Suppl.13):E195-E204.
[27] 陈秋萍,徐生祥,刘庆友,等.脯氨酸对母猪繁殖性能影响的研究进展[J].中国畜牧兽医,2017,44(3):767-772.
[28] 伍国耀,武振龙,戴兆来,等.猪对"非必需氨基酸"的营养需要[J].饲料工业,2013,34(16):60-64.
[29] 林可.氨基酸对妊娠母猪繁殖性能的影响及其作用机理(续完)[J].国外畜牧学(猪与禽),2010,30(5):39-42.
[30] 陈昭光.PPARγ对胎盘滋养层细胞氨基酸转运体的调节及机制研究[D].硕士学位论文.上海:第二军医大学,2014.
[31] 王仁华,刘晓兰,王琤韡.亮氨酸对母猪的营养作用与应用[J].饲料研究,2011(11):13-15.
[32] KIM J Y,BURGHARDT R C,WU G Y,et al.Select nutrients in the ovine uterine lumen.Ⅶ.Effects of arginine,leucine,glutamine,and glucose on trophectoderm cell signaling,proliferation,and migration[J].Biology of Reproduction,2011,84(1):62-69.  
[33] AGOSTINELLI E.Role of polyamines,their analogs and transglutaminases in biological and clinical perspectives[J].Amino Acids,2012,42(2/3):397-409.
[34] ZHANG X,WANG H M,QIAN D,et al.Effect of NO on the expression of VEGF and its receptors in mouse uterus during peri-implantation[J].Acta Zoologica Sinica,2004,50(1):55-61.
文章导航

/