动物营养学报 >

2019 , Vol. 31 >Issue 11: 5256 - 5261

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.11.042

饲料科学与技术 Feed science and technology

艾蒿水提物对脂多糖刺激的肉仔鸡小肠黏膜形态的影响

  • 张凌会 ,
  • 杜海东 ,
  • 毛晨羽 ,
  • 张鹏飞 ,
  • 金晓 ,
  • 徐元庆 ,
  • 史彬林
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  • 内蒙古农业大学动物科学学院, 呼和浩特 010018
张凌会(1993-),女,内蒙古巴彦淖尔人,博士研究生,从事动物环境与营养的研究。E-mail:Zhanglinghui19@yeah.net

收稿日期: 2019-04-15

  网络出版日期: 2019-11-19

基金资助

国家自然科学基金项目（31660674）

收起

Effects of Artemisia argyi Aqueous Extract on Intestinal Mucosal Morphology of Broilers Stimulated with Lipopolysaccharide

  • ZHANG Linghui ,
  • DU Haidong ,
  • MAO Chenyu ,
  • ZHANG Pengfei ,
  • JIN Xiao ,
  • XU Yuanqing ,
  • SHI Binlin
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  • College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China

Received date: 2019-04-15

  Online published: 2019-11-19

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摘要

本试验旨在研究艾蒿水提物（AAE）对脂多糖（LPS）刺激的肉仔鸡小肠黏膜形态的影响。选用1日龄健康爱拔益加（AA）肉仔鸡96只，随机分为4个处理（每个处理设6个重复，每个重复4只鸡），处理1和2饲喂基础饲粮，处理3和4饲喂在基础饲粮中添加1 000 mg/kg AAE的试验饲粮。于试验第14、16、18、20天时，处理2和4肉仔鸡腹腔注射500 μg/kg BW LPS溶液，处理1和3肉仔鸡注射等量生理盐水。试验期共21 d。结果表明：当饲粮中不添加AAE（基础饲粮）时，注射LPS的肉仔鸡十二指肠和空肠绒毛高度显著低于注射生理盐水的肉仔鸡（P<0.05），但饲粮中添加AAE可缓解因LPS引起的肉仔鸡绒毛高度的下降，且AAE与LPS存在显著互作效应（P<0.05）；而各处理间回肠绒毛高度、隐窝深度以及绒毛高度/隐窝深度均无显著差异（P>0.05）。上述结果提示，AAE可在一定程度上缓解LPS对肉仔鸡免疫应激所带来的肠黏膜损伤。

关键词： 艾蒿水提物; 肉仔鸡; 肠黏膜形态; 脂多糖

本文引用格式

张凌会 , 杜海东 , 毛晨羽 , 张鹏飞 , 金晓 , 徐元庆 , 史彬林 . 艾蒿水提物对脂多糖刺激的肉仔鸡小肠黏膜形态的影响[J]. 动物营养学报, 2019 , 31(11) : 5256 -5261 . DOI: 10.3969/j.issn.1006-267x.2019.11.042

Abstract

This experiment was conducted to investigate the effects of Artemisia argyi aqueous extract (AAE) on intestinal mucosal morphology of broilers stimulated with lipopolysaccharide (LPS). A total of 96 one-day-old AA broilers were randomly divided into 4 treatments (6 replicates per treatment, 4 broilers per replicate). Treatments 1 and 2 were fed a basal diet, and treatments 3 and 4 were fed the basal diet supplemented with 1 000 mg/kg AAE. On days 14, 16, 18 and 20, respectively, the broilers in treatments 2 and 4 were intraperitoneally injected with LPS solution at a dose of 500 μg/kg BW, and the broilers in treatments 1 and 3 were injected with the same amount of normal saline. The test period was 21 days. The results showed as follows:when no AAE was added in diets, the villus height of duodenum and jejunum of broilers injected with LPS was significantly lower than that of broilers injected with normal saline (P<0.05), but the addition of AAE to the diet alleviated the decrease of villus height caused by LPS, and there was significant interaction between AAE and LPS (P<0.05); but for ileum, there were no significant differences in villus height, crypt depth, and the ratio of villus height to crypt depth (P>0.05). The above results suggest that AAE can alleviate the intestinal mucosal damage caused by immune stress in broilers stimulated with LPS to a certain extent.

Key words： Artemisia argyi aqueous extract; broiler; intestinal mucosal morphology; lipopolysaccharide

参考文献

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