[1] 王云鹏,马越.养殖业抗生素的使用及其潜在危害[J].中国抗生素杂志,2008,33(9):519-523.
[2] ZHANG L,GU J,WANG X J,et al.Fate of antibiotic resistance genes and mobile genetic elements during anaerobic co-digestion of Chinese medicinal herbal residues and swine manure[J].Bioresource Technology,2018,250:799-805.
[3] CHIU Y H,LIN S L,TSAI J J,et al.Probiotic actions on diseases:implications for therapeutic treatments[J].Food & Function,2014,5(4):625-634.

[4] LIAO S F,NYACHOTI M.Using probiotics to improve swine gut health and nutrient utilization[J].Animal Nutrition,2017,3(4):331-343.

[5] QIU Y Q,JIANG Z Y,HU S L,et al.
Lactobacillus plantarum enhanced IL-22 production in natural killer (NK) cells that protect the integrity of intestinal epithelial cell barrier damaged by enterotoxigenic
Escherichia coli[J].International Journal of Molecular Sciences,2017,18(11):2409.
[6] WU Y P,ZHU C,CHEN Z,et al.Protective effects of
Lactobacillus plantarum on epithelial barrier disruption caused by enterotoxigenic
Escherichia coli in intestinal porcine epithelial cells[J].Veterinary Immunology and Immunopathology,2016,172:55-63.
[7] YI H B,WANG L,XIONG Y X,et al.Effects of
Lactobacillus reuteri LR1 on the growth performance,intestinal morphology,and intestinal barrier function in weaned pigs[J].Journal of Animal Science,2018,96(6):2342-2351.

[8] YANG K M,JIANG Z Y,ZHENG C T,et al.Effect of
Lactobacillus plantarum on diarrhea and intestinal barrier function of young piglets challenged with enterotoxigenic
Escherichia coli K88[J].Journal of Animal Science,2014,92(4):1496-1503.

[9] WANG X Q,YANG F,LIU C,et al.Dietary supplementation with the probiotic
Lactobacillus fermentum I5007 and the antibiotic aureomycin differentially affects the small intestinal proteomes of weanling piglets[J].The Journal of Nutrition,2012,142(1):7-13.

[10] SUO C,YIN Y S,WANG X N,et al.Effects of
Lactobacillus plantarum ZJ316 on pig growth and pork quality[J].BMC Veterinary Research,2012,8:89.
[11] GAO P F,MA C,SUN Z,et al.Feed-additive probiotics accelerate yet antibiotics delay intestinal microbiota maturation in broiler chicken[J].Microbiome,2017,5(1):91.
[12] YI H B,WANG L,XIONG Y X,et al.
Lactobacillus reuteri LR1 improved expression of genes of tight junction proteins via the MLCK pathway in IPEC-1 cells during infection with enterotoxigenic
Escherichia coli K88[J].Mediators of Inflammation,2018,2018:6434910.
[13] YANG J J,WANG C L,LIU L Q,et al.
Lactobacillus reuteri KT260178 supplementation reduced morbidity of piglets through its targeted colonization,improvement of cecal microbiota profile,and immune functions[J].Probiotics and Antimicrobial Proteins,2019,doi:10.1007/s12602-019-9514-3.
[14] CUI C,SHEN C J,JIA G,et al.Effect of dietary
Bacillus subtilis on proportion of Bacteroidetes and Firmicutes in swine intestine and lipid metabolism[J].Genetics and Molecular Research,2013,12(2):1766-1776.

[15] MENG Q W,YAN L,AO X,et al.Influence of probiotics in different energy and nutrient density diets on growth performance,nutrient digestibility,meat quality,and blood characteristics in growing-finishing pigs[J].Journal of Animal Science,2010,88(10):3320-3326.

[16] SHENG Q K,ZHOU K F,HU H M,et al.Effect of
Bacillus subtilis Natto on meat quality and skatole content in TOPIGS pigs[J].Asian-Australasian Journal of Animal Sciences,2016,29(5):716-721.
[17] LAN R X,LEE S I,KIM I H.Effects of multistrain probiotics on growth performance,nutrient digestibility,blood profiles,faecal microbial shedding,faecal score and noxious gas emission in weaning pigs[J].Journal of Animal Physiology and Animal Nutrition,2016,100(6):1130-1138.

[18] ALEXOPOULOS C,GEORGOULAKIS I E,TZIVARA A,et al.Field evaluation of the efficacy of a probiotic containing
Bacillus licheniformis and
Bacillus subtilis spores,on the health status and performance of sows and their litters[J].Journal of Animal Physiology and Animal Nutrition,2004,88(11/12):381-392.
[19] WANG Y,WU Y P,WANG B K,et al.Effects of probiotic
Bacillus as a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets[J].AMB Express,2017,7(1):52.
[20] 田志梅,蒋宗勇,王丽,等.益生菌的功能及其在生猪养殖产业中的应用[J].动物营养学报,2019,31(3):1020-1030.
[21] ZHANG H,TSAO R.Dietary polyphenols,oxidative stress and antioxidant and anti-inflammatory effects[J].Current Opinion in Food Science,2016,8:33-42.
[22] GONZALES G B,SMAGGHE G,GROOTAERT C,et al.Flavonoid interactions during digestion,absorption,distribution and metabolism:a sequential structure-activity/property relationship-based approach in the study of bioavailability and bioactivity[J].Drug Metabolism Reviews,2015,47(2):175-190.

[23] SMITH B N,DILGER R N.Immunomodulatory potential of dietary soybean-derived isoflavones and saponins in pigs[J].Journal of Animal Science,2018,96(4):1288-1304.

[24] NORRBY M,MADSEN M,SARAVIA F,et al.Genistein alters the release of oxytocin,prostaglandins,cortisol and LH during insemination in gilts[J].Reproduction in Domestic Animals,2011,46(2):316-324.

[25] CHENG C S,XIA M,ZHANG X M,et al.Supplementing oregano essential oil in a reduced-protein diet improves growth performance and nutrient digestibility by modulating intestinal bacteria,intestinal morphology,and antioxidative capacity of growing-finishing pigs[J].Animals,2018,8(9):159.
[26] ARIZA-NIETO C,BAIDOO S K,HATHAWAY M R.饲料中添加植物提取物对断奶-育肥猪生长性能及胴体品质的影响[J].纪少丽,李爱花,姜洁凌译.中国畜牧杂志,2013,49(8):61-67.
[27] 史东辉,陈俊锋,赵连生,等.唇形科植物提取物对肉鸡血清抗氧化功能和鸡肉脂类氧化的影响研究[J].中国畜牧杂志,2013,49(7):63-67.
[28] 史东辉,李爱花,马学会,等.植物提取物对肉仔鸡生产和屠宰性能、血清IgG和粪便球虫卵囊数量的影响[J].中国畜牧杂志,2013,49(6):61-64.
[29] BAKKALI F,AVERBECK S,AVERBECK D,et al.Biological effects of essential oils-a review[J].Food and Chemical Toxicology,2008,46(2):446-475.

[30] SMITH B N,MORRIS A,OELSCHLAGER M L,et al.Effects of dietary soy isoflavones and soy protein source on response of weanling pigs to porcine reproductive and respiratory syndrome viral infection[J].Journal of Animal Science,2019,97(7):2989-3006.

[31] SIROTKIN A V,HRABOVSZKA S,ŠTOCHMAL'OVÁ A,et al.Effect of quercetin on ovarian cells of pigs and cattle[J].Animal Reproduction Science,2019,205:44-51.
[32] GUO Q,XUAN M F,LUO Z B,et al.Baicalin improves IVM of pig oocytes and subsequent preimplantation embryo development by inhibiting apoptosis[J].Reproduction,Fertility and Development,2019,31(5):983-992.

[33] CUI K,WANG Q,WANG S Q,et al.The facilitating effect of Tartary buckwheat flavonoids and
Lactobacillus plantarum on the growth performance,nutrient digestibility,antioxidant capacity,and fecal microbiota of weaned piglets[J].Animals,2019,9(11):986.
[34] MA T,CHEN D D,TU Y,et al.Dietary supplementation with mulberry leaf flavonoids inhibits methanogenesis in sheep[J].Animal Science Journal,2017,88(1):72-78.

[35] KONG L X,YANG C T,DONG L F,et al.Rumen fermentation characteristics in pre-and post-weaning calves upon feeding with mulberry leaf flavonoids and
Candida tropicalis individually or in combination as a supplement[J].Animals,2019,9(11):990.
[36] 贾淑庚,任灵肖,梁剑峰,等.丝兰属植物提取物对蛋鸡生产性能及蛋品质的影响[J].中国家禽,2014,36(16):34-37.
[37] REN M Q,KUHN G,WEGNER J,et al.Feeding daidzein to late pregnant sows influences the estrogen receptor beta and type 1 insulin-like growth factor receptor mRNA expression in newborn piglets[J].Journal of Endocrinology,2001,170(1):129-135.

[38] 李成洪,王孝友,杨睿,等.植物提取物饲料添加剂对生长猪生产性能的影响[J].饲料工业,2012,33(17):14-16.
[39] 刘则学,彭首策,沈峰,等.植物提取物绿原酸对仔猪生长性能和经济效益的影响研究[J].养猪,2013(2):43-44.
[40] 李泽政,肖英平,洪奇华,等.樟属植物提取物作为畜禽除臭剂的应用研究[J].饲料研究,2014(17):18-21.
[41] 陈鹏,单安山.女贞子对肉仔鸡生长性能和胴体品质的影响[J].中国饲料,2009(4):15-17.
[42] 郭晓秋,单安山,曲哲会.女贞子对动物免疫功能的影响[J].中国饲料,2006(1):9-11.
[43] 李建平,单安山,陈志辉,等.女贞子对断奶仔猪生长性能和血液生化指标的影响[J].东北农业大学学报,2011,42(9):26-30.
[44] 郭巧萍.抗生素替代物对畜禽生产的影响研究进展[J].山西农业科学,2012,40(5):553-554,558.
[45] OLAGARAY K E,BROUK M J,MAMEDOVA L K,et al.Dietary supplementation of
Scutellaria baicalensis extract during early lactation decreases milk somatic cells and increases whole lactation milk yield in dairy cattle[J].PLoS One,2019,14(1):e0210744.
[46] BAI X M,YAN X,XIE L Q,et al.Effects of pre-slaughter stressor and feeding preventative Chinese medicinal herbs on glycolysis and oxidative stability in pigs[J].Animal Science Journal,2016,87(8):1028-1033.

[47] SU J Y,ZHU Q,ZHAO Y,et al.Dietary supplementation with Chinese herbal residues or their fermented products modifies the colonic microbiota,bacterial metabolites,and expression of genes related to colon barrier function in weaned piglets[J].Frontiers in Microbiology,2018,9:3181.
[48] 鲁慧杰,陈卫东,田志梅,等.丝兰提取物生理功能及其在养殖生产上的应用[J].动物营养学报,2019,31(5):1990-2001.
[49] 崔艺燕,田志梅,李贞明,等.植物提取物的生物学功能及其在仔猪生产上的应用[J].中国畜牧兽医,2018,45(12):3419-3430.
[50] KUMALASARI I D,NISHI K,PUTRA A B N,et al.Activation of macrophages stimulated by the bengkoang fiber extract through Toll-like receptor 4[J].Food & Function,2014,5(7):1403-1408.

[51] GURUSMATIKA S,NISHI K,HARMAYANI E,et al.Immunomodulatory activity of octenyl succinic anhydride modified porang (
Amorphophallus oncophyllus) glucomannan on mouse macrophage-like J774.1 cells and mouse primary peritoneal macrophages[J].Molecules,2017,22(7):1187.
[52] 田明明,刘奇.天然多糖在免疫调节活性方面的研究进展[J].云南中医中药杂志,2018,39(8):80-82.
[53] 李万坤,郭福存,赵兴绪.天然免疫活性多糖替代抗生素添加剂的作用研究[J].家畜生态学报,2007,28(1):10-17.
[54] GERRITSEN R,VAN DER AAR P,MOLIST F.Insoluble nonstarch polysaccharides in diets for weaned piglets[J].Journal of Animal Science,2012,90(Suppl.4):318-320.
[55] CLARK O G,MOEHN S,EDEOGU I,et al.Manipulation of dietary protein and nonstarch polysaccharide to control swine manure emissions[J].Journal of Environmental Quality,2005,34(5):1461-1466.

[56] 侯凯.木聚糖酶与小刺猴头多糖替代抗生素在肉鸡生产中的应用[D].硕士学位论文.长春:吉林农业大学,2017.
[57] 北京爱地科技有限公司技术部.免疫多糖在家禽饲料中替代抗生素的饲喂试验[C]//中国禽业发展大会暨中国畜牧业协会禽业分会第二届会员代表大会论文集.北京:中国畜牧业协会,2007:3.
[58] 李静.酵母细胞壁多糖替代抗生素对肉鸡生产性能的影响[J].内江科技,2017,38(11):134-135.
[59] MA X,TIAN Z,XIONG Y,et al.Effect of yeast polysaccharide on meat quality of finishing pigs[J].Journal of Animal Science,2017,95(Suppl.4):184.
[60] 王露懿,朱华旭.多糖资源的开发应用现状及存在问题分析[J].药物生物技术,2018,25(1):90-94.
[61] FILLION M,VALOIS-PAILLARD G,LORIN A,et al.Membrane interactions of synthetic peptides with antimicrobial potential:effect of electrostatic interactions and amphiphilicity[J].Probiotics and Antimicrobial Proteins,2015,7(1):66-74.

[62] LAUGHLIN T F,AHMAD Z.Inhibition of
Escherichia coli ATP synthase by amphibian antimicrobial peptides[J].International Journal of Biological Macromolecules,2010,46(3):367-374.

[63] YEAMAN M R,YOUNT N Y.Mechanisms of antimicrobial peptide action and resistance[J].Pharmacological Reviews,2003,55(1):27-55.

[64] 李方方,苏航,张勇,等.饲粮添加复合抗菌肽与包被氧化锌对断奶仔猪生长性能及血清生化指标的影响[J].动物营养学报,2015,27(9):2811-2819.
[65] TANG Z R,YIN Y L,ZHANG Y M,et al.Effects of dietary supplementation with an expressed fusion peptide bovine lactoferricin-lactoferrampin on performance,immune function and intestinal mucosal morphology in piglets weaned at age 21 d[J].British Journal of Nutrition,2009,101(7):998-1005.
[66] 皮灿辉,彭永鹤,李永新,等.抗菌肽制剂对母猪死胎率和仔猪成活率的影响[J].中国畜牧兽医,2008,35(6):90-91.
[67] BAO H,SHE R,LIU T,et al.Effects of pig antibacterial peptides on growth performance and intestine mucosal immune of broiler chickens[J].Poultry Science,2009,88(2):291-297.

[68] 郭文洁,高锋,吕磊,等.腹泻鸡粪培养蝇蛆抗菌肽对患病鸡疗效的研究[J].黑龙江畜牧兽医,2017(9):154-156.
[69] GEBRU E,LEE J S,SON J C,et al.Effect of probiotic-,bacteriophage-,or organic acid-supplemented feeds or fermented soybean meal on the growth performance,acute-phase response,and bacterial shedding of grower pigs challenged with
Salmonella enterica serotype Typhimurium[J].Journal of Animal Science,2010,88(12):3880-3886.

[70] CREUS E,PÉREZ J F,PERALTA B,et al.Effect of acidified feed on the prevalence of
Salmonella in market-age pigs[J].Zoonoses and Public Health,2007,54(8):314-319.

[71] ERIKSEN J,NØRGAARD J V,POULSEN H D,et al.Effects of acidifying pig diets on emissions of ammonia,methane,and sulfur from slurry during storage[J].Journal of Environmental Quality,2014,43(6):2086-2095.

[72] HAMID H,SHI H Q,MA G Y,et al.Influence of acidified drinking water on growth performance and gastrointestinal function of broilers[J].Poultry Science,2018,97(10):3601-3609.

[73] RAGAA N M,KORANY R M S.Studying the effect of formic acid and potassium diformate on performance,immunity and gut health of broiler chickens[J].Animal Nutrition,2016,2(4):296-302.

[74] TRAN T H T,EVERAERT N,BINDELLE J.Review on the effects of potential prebiotics on controlling intestinal enteropathogens
Salmonella and
Escherichia coli in pig production[J].Journal of Animal Physiology and Animal Nutrition,2018,102(1):17-32.