动物营养学报 >

2020 , Vol. 32 >Issue 4: 1850 - 1858

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.04.044

特种经济动物营养与饲料 SPECIAL ECONOMIC ANIMAL NUTRITION AND FEED

饲粮泛酸添加水平对冬毛生长期水貂生产性能、血清生化指标及毛囊发育的影响

  • 王卓 ,
  • 刘晗璐 ,
  • 刘可园 ,
  • 张海华 ,
  • 史鸿鹏 ,
  • 张新宇 ,
  • 陈丽红 ,
  • 李光玉
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  • 1. 中国农业科学院特产研究所, 吉林省特种经济动物分子生物学省部共建国家重点实验室, 长春 130112;
    2. 河北科技师范学院动物科技学院, 河北省特色动物种质资源挖掘与创新重点实验室, 秦皇岛 066004
王卓(1986-),女,吉林吉林人,硕士,研究方向为动物营养与饲料科学。E-mail:wangzhuo6321@126.com

收稿日期: 2019-10-10

  网络出版日期: 2020-04-16

基金资助

中国农业科学院创新工程经费资助项目（CAAS-ASTIP-2019-ISAPS）；河北省青年拔尖人才项目；河北省高校百名优秀创新人才项目；河北省自然科学基金面上项目（C2019407111）

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Effects of Dietary Pantothenic Acid Supplemental Level on Performance, Serum Biochemical Indices and Hair Follicle Development of Minks during Winter Fur-Growing Period

  • WANG Zhuo ,
  • LIU Hanlu ,
  • LIU Keyuan ,
  • ZHANG Haihua ,
  • SHI Hongpeng ,
  • ZHANG Xinyu ,
  • CHEN Lihong ,
  • LI Guangyu
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  • 1. State Key Laboratory of Special Economic Animal Molecular Biology, Institute of Special Animal and Plant Science, Chinese Academy of Agriculture Sciences, Changchun 130112, China;
    2. Hebei Normal University of Science and Technology, Hebei Key Laboratory of Specialty Animal Germplasm Resources Innovation and Utilization, Qinhuangdao 066004, China

Received date: 2019-10-10

  Online published: 2020-04-16

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摘要

本试验旨在研究饲粮泛酸添加水平对冬毛生长期水貂生产性能、血清生化指标及毛囊发育的影响。采用单因子试验设计，选用（140±5）日龄、平均体重（1.94±0.19）kg的健康雄性短毛黑水貂60只，随机分成6组，每组10个重复，每个重复1只。基础饲粮中泛酸含量为8.91 mg/kg，各组饲粮泛酸添加水平分别为0（Ⅰ组，对照组）、10（Ⅱ组）、20（Ⅲ组）、30（Ⅳ组）、40（Ⅴ组）、80 mg/kg（Ⅵ组）。预试期5 d，正试期65 d。结果表明：1）Ⅵ组水貂鲜皮重显著高于Ⅰ~Ⅳ组（P<0.05）。2）随着饲粮泛酸添加水平的增加，Ⅰ~Ⅴ组血清泛酸含量逐渐增加，但差异不显著（P>0.05），Ⅵ组血清泛酸含量显著高于其他各组（P<0.05）；各组之间肝脏泛酸含量差异不显著（P>0.05）。3）Ⅲ组血清球蛋白（GLOB）含量显著高于Ⅰ、Ⅱ和Ⅴ组（P<0.05），Ⅲ组血清胆固醇（CHO）和高密度脂蛋白胆固醇（HDL-C）含量极显著低于Ⅴ和Ⅵ组（P<0.05）。4）Ⅱ组冬毛生长前期血清褪黑激素含量显著低于Ⅰ组（P<0.05），Ⅲ组显著高于Ⅱ组（P<0.01），Ⅳ、Ⅴ、Ⅵ组极显著低于Ⅲ组（P<0.01）。Ⅲ组冬毛生长后期血清褪黑激素含量显著低于其他各组（P<0.05）。5）Ⅵ组毛囊深度显著高于Ⅳ组（P<0.05），极显著高于Ⅰ组（P<0.01）；各组毛囊密度和次级毛囊密度/初级毛囊密度无显著差异（P>0.05）。综上所述，饲粮泛酸添加水平为20 mg/kg时（饲粮中总泛酸含量为28.91 mg/kg），水貂皮长增加2.37%，同时增加了血清GLOB含量，降低了血清CHO和HDL-C含量；饲粮泛酸添加水平为80 mg/kg时（饲粮中总泛酸含量为88.91 mg/kg），降低了水貂冬毛生长前期血清褪黑激素含量，增加了毛囊深度，增加了水貂鲜皮重。

关键词： 泛酸; 水貂; 冬毛生长期; 生产性能; 血清生化指标

本文引用格式

王卓 , 刘晗璐 , 刘可园 , 张海华 , 史鸿鹏 , 张新宇 , 陈丽红 , 李光玉 . 饲粮泛酸添加水平对冬毛生长期水貂生产性能、血清生化指标及毛囊发育的影响[J]. 动物营养学报, 2020 , 32(4) : 1850 -1858 . DOI: 10.3969/j.issn.1006-267x.2020.04.044

Abstract

This experiment was conducted to evaluate the effects of dietary pantothenic acid supplemental level on performance, serum biochemical indices and hair follicle development of minks during winter fur-growing period. A single factor test design was adopted, sixty healthy male short haired black minks at (140±5) days of age with similar body weight of (1.94±0.19) kg were randomly divided into 6 groups with 10 replicates per group and 1 mink per replicate. The content of pantothenic acid in the basal diet was 8.91 mg/kg, and dietary pantothenic acid supplemental level of each group were 0 (group Ⅰ, control group), 10 (group Ⅱ), 20 (group Ⅲ), 30 (group Ⅳ), 40 (group Ⅴ) and 80 mg/kg (group Ⅵ), respectively. The pre-experimental period lasted for 5 days, and the experimental period lasted for 65 days. The results showed as follows:1) the fresh pelt weight of minks of group Ⅵ was significantly higher than groups Ⅰ to Ⅳ (P<0.05). 2) With the dietary pantothenic acid supplemental level increased, the serum pantothenic acid content of groups Ⅰ to Ⅴ was increased, but had no significant difference (P>0.05), and the serum pantothenic acid content of group Ⅵ was significantly higher than that of other groups (P<0.05); there was no significant difference on the liver pantothenic acid content among all groups (P>0.05). 3) The serum globulin content of group Ⅲ was significantly higher than that of groups Ⅰ, Ⅱ and Ⅴ (P<0.05), the contents of cholesterol (CHO) and high density lipoprotein cholesterol (HDL-C) in serum of group Ⅲ were significantly lower than those of groups Ⅴ and Ⅵ (P<0.05). 4) The serum melatonin content in early stage of winter fur-growing period of group Ⅱ was significantly lower than that of group Ⅰ (P<0.05), group Ⅲ was significantly higher than that of group Ⅱ (P<0.01), and groups Ⅳ, Ⅴ and Ⅵ was significantly lower than that of group Ⅲ (P<0.01). The serum melatonin content in later stage of winter fur-growing period of group Ⅲ was significantly lower than that of other groups (P<0.05). 5) The hair follicle depth of group Ⅵ was significantly higher than that of group Ⅳ (P<0.05), and significantly higher than that of group Ⅰ (P<0.01), there were no significant differences on the hair follicle density and secondary hair follicle density/primary hair follicle density among all groups (P>0.05). In conclusion, when dietary pantothenic acid supplemental level is 20 mg/kg (dietary total pantothenic acid content is 28.91 mg/kg), the pelt length of minks increases by 2.37%, the serum GLOB content is increased, and the contents of CHO and HDL-C in serum are reduced; when dietary pantothenic acid supplemental level is 80 mg/kg (dietary total pantothenic acid content is 88.91 mg/kg), the serum melatonin content of minks in early stage of winter fur-growing period is reduced, and the fresh pelt weight is increased.

Key words： pantothenic acid; minks; winter fur-growing period; performance; serum biochemical indices

参考文献

[1] SMITH C M,SONG W O.Comparative nutrition of pantothenic acid[J].The Journal of Nutritional Biochemistry,1996,7(6):312-321.  
[2] WILLIAMS R J,LYMAN C M,GOODYEAR G H,et al."Pantothenic acid",a growth determinant of universal biological occurrence[J].Journal of the American Chemical Society,1933,55(7):2912-2927.  
[3] MORGAN A F,SIMMS H D.Greying of fur and other disturbances in several species due to a vitamin deficiency:three figures[J].The Journal of Nutrition,1940,19(3):233-250.  
[4] PETERSON W H,PETERSON M S.Relationship of bacteria to vitamins and the other growth factor[J].Bacteriological Reviews,1945,9:49-86.
[5] SANDZA J G,CERECEDO L R.Requirement of the mouse for pantothenic acid and for a new factor of the vitamin B complex:two figures[J].The Journal of Nutrition,1941,21(6):609-615.  
[6] FENTON P F,COWGILL G R,STONE M A,et al.The nutrition of the mouse:Ⅷ.Studies on pantothenic acid,biotin,inositol and p-aminobenzoic acid[J].The Journal of Nutrition,1950,42(2):257-269.  
[7] BEER A E,SCOTT M L,NESHEIM M C.The effects of graded levels of pantothenic acid on the breeding performance of white leghorn pullets[J].British Poultry Science,1963,4(3):243-253.  
[8] GRIES C L,SCOTT M L.The pathology of thiamin,riboflavin,pantothenic acid and niacin deficiencies in the chick[J].The Journal of Nutrition,1972,102(10):1269-1285.  
[9] KRATZER F H,WILLIAMS D.The pantothenic acid requirement of poults for early growth[J].Poultry Science,1948,27(4):518-523.  
[10] RAM T.A histopathologic study of chicks deficient in pantothenic acid[J].Poultry Science,1949,28(3):425-430.  
[11] WINTROBE M M,FOLLIS R H,ALCAYAGA R,et al.Pantothenic acid deficiency in swine[J].Bulletin Johns Hopkins Hospital,1943,73:313-342.
[12] 祁树彬.貉维生素缺乏的临床症状及其防治[J].养殖技术顾问,2009(1):123.
[13] 赵楠.日粮泛酸水平对生长獭兔生产性能、抗氧化性能和脂肪代谢的影响[D].硕士学位论文.泰安:山东农业大学,2016.
[14] NRC.Nutrient requirements of mink and foxes[S].2nd ed.Washington,D.C.:National Academy Press,1982.
[15] CAMARGO F B,Jr,GASPAR L R,CAMPOS P M M.Skin moisturizing effects of panthenol-based formulations[J].Journal of Cosmetic Science,2011,62(4):361-370.
[16] 王卓,李光玉,刘可园.饲粮泛酸水平对育成期水貂生长性能、营养物质消化率、氮代谢和血清生化指标的影响[J].动物营养学报,2020,32(1):
[17] 张肖,王宝维,岳斌,等.泛酸对5-16周龄五龙鹅生长性能、屠宰性能、肌肉品质、营养物质利用率及血清生化指标的影响[J].动物营养学报,2015,27(11):3411-3419.
[18] 汪梦萍.兽医微生物学[M].北京:化学工业出版社,2006.
[19] AVOGARO P,BON G B,FUSELLO M.Effect of pantethine on lipids,lipoproteins and apolipoproteins in man[J]. Current Therapeutic Research-Clinical and Experimental,1983,33(3):488-493.
[20] 王孝胜,张志明,毕全秀,等.埋植褪黑激素促进水貂生长、换毛、毛皮早熟的试验报告[J].毛皮动物饲养,1995(2):3-5.
[21] 孔庆松,刘志平,景松岩,等.褪黑激素促进水貂冬皮早熟的研究[J].野生动物,1995(4):22-26.
[22] 陈玉林,张小辉.不同绵羊品种褪黑激素的季节性及昼夜变化规律研究[J].家畜生态学报,2005,26(1):35-38.
[23] 王昊.辽宁绒山羊绒毛生长、血液中相关激素变化及皮肤中基因的表达分析[D].硕士学位论文.沈阳:沈阳农业大学,2016.
[24] 杨延辉,肖春玲.泛酸的功能和生物合成[J].生命的化学,2008,28(4):448-452.
[25] 李维克.外源性褪黑激素对蓝狐、蓝霜狐及乌苏里貉毛皮性状影响的研究[D].硕士学位论文.哈尔滨:东北林业大学,2009.
[26] KOBAYASHI D,KUSAMA M,ONDA M,et al.The effect of pantothenic acid deficiency on keratinocyte proliferation and the synthesis of keratinocyte growth factor and collagen in fibroblasts[J].Journal of Pharmacological Sciences,2011,115(2):230-234.  
[27] KELLY G S.Pantothenic acid.Monograph[J].Alternative Medicine Review:A Journal of Clinical Therapeutic,2011,16(3):263-274.
[28] GAISA N T,KÖSTER J,REINARTZ A,et al.Expression of acyl-CoA synthetase 5 in human epidermis[J].Histology and Histopathology,2008,23(4):451-458.
[29] WIEDERHOLT T,HEISE R,SKAZIK C,et al.Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts[J].Experimental Dermatology,2009,18(11):969-978.  
[30] WEIMANN B I,HERMANN D.Studies on wound healing:effects of calcium D-pantothenate on the migration,proliferation and protein synthesis of human dermal fibroblasts in culture[J].International Journal for Vitamin and Nutrition Research,1999,69(2):113-119.  
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