综述 REVIEW

糖类调控动物采食的研究进展

  • 陈履双 ,
  • 王丽娜
展开
  • 华南农业大学动物科学学院, 广东省动物营养调控重点实验室, 广州 510642
陈履双(1993-),女,山东菏泽人,硕士研究生,从事动物采食调控方面的研究。E-mail:2377340358@qq.com

收稿日期: 2020-03-28

  网络出版日期: 2020-11-16

基金资助

国家自然科学基金面上项目(31672464,31572480)

Recent Advance on Regulation of Animal Feeding by Sugar

  • CHEN Lvshuang ,
  • WANG Lina
Expand
  • Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China

Received date: 2020-03-28

  Online published: 2020-11-16

摘要

糖类可分为单糖、双糖和多糖,不仅是人体内产生热能的主要物质,对动物采食也具有重要调控作用。采食行为主要受下丘脑食欲中枢的稳态调节,下丘脑弓状核可直接传导神经信号,也可分泌刺鼠相关蛋白(AgRP)和神经肽Y (NPY)等调节采食;动物在非饥饿状态下摄入可口食物会传入大脑奖赏系统产生奖赏效应,从而促进采食奖赏行为的发生,主要涉及到中脑边缘系统的多巴胺奖赏系统。目前对于不同糖类对畜禽采食量的调控和作用机制尚不完善,本文依据大量国内外研究成果对糖类调控畜禽采食行为的研究进展作一综述。

本文引用格式

陈履双 , 王丽娜 . 糖类调控动物采食的研究进展[J]. 动物营养学报, 2020 , 32(11) : 5030 -5037 . DOI: 10.3969/j.issn.1006-267x.2020.11.007

Abstract

Sugar, which can be divided into monosaccharides, disaccharides and polysaccharides, is one of the most important energy sources of an organism, and also play a significant role in feeding regulate. It is believed that feeding behavior is under the complex control of hypothalamic appetite center and midbrain dopamine reward system. The arcuate nucleus of hypothalamus could both conduct neural signal directly and secrete feeding-related peptides such as agouti-related protein (AgRP) and neuropeptide Y (NPY). Animals under non starvation condition, consumption of delicious food activates reward system mainly in midbrain thus to promote food intake. So far, the effects of different sugars on animal feeding regulation are incomplete yet, based on a large number of domestic and foreign studies, this article gave a review of the regulation effect of sugar on animal feeding behavior.

参考文献

[1] HAN P F,MOHEBBI M,SEO H S,et al.Sensitivity to sweetness correlates to elevated reward brain responses to sweet and high-fat food odors in young healthy volunteers[J].Neuroimage,2020,208:116413.
[2] ELLIOTT S S,KEIM N L,STERN J S,et al.Fructose,weight gain,and the insulin resistance syndrome[J].The American Journal of Clinical Nutrition,2002,76(5):911-922.  
[3] BOCARSLY M E,POWELL E S,AVENA N M,et al.High-fructose corn syrup causes characteristics of obesity in rats:increased body weight,body fat and triglyceride levels[J].Pharmacology Biochemistry and Behavior,2010,97(1):101-106.  
[4] LIU J J,MUKHERLEE D,HARITAN D,et al.High on food:the interaction between the neural circuits for feeding and for reward[J].Frontiers in Biology,2015,10(2):165-176.  
[5] SUZUKI K,SIMPSON K A,MINNION J S,et al.The role of gut hormones and the hypothalamus in appetite regulation[J].Endocrine Journal,2010,57(5):59-72.
[6] ESSNER R A,SMITH A G,JAMNIK A A,et al.AgRP neurons can increase food intake during conditions of appetite suppression and inhibit anorexigenic parabrachial neurons[J].The Journal of Neuroscience,2017,37(36):8678-8687.  
[7] WISE R A.Role of brain dopamine in food reward and reinforcement[J].Philosophical Transactions of the Royal Society B:Biological Sciences,2006,361(1471):1149-1158.  
[8] 李永祥,王嘉雯,江青艳,等.采食的奖赏性调节及其机制[J].中国畜牧杂志,2018,54(9):10-15.
[9] BERTHOUD H R,MORRISON C.The brain,appetite,and obesity[J].Annual Review of Psychology,2008,59:55-92.
[10] 李万华.糖类添加剂在生猪生产中的应用[J].山东畜牧兽医,2013,34(6):84.
[11] 孙克年.糖类添加剂在养鸡生产中应用[J].中国禽业导刊,1998(1):14.
[12] MA X S,ZUBCEVIC L,ASHCROFT F M.Glucose regulates the effects of leptin on hypothalamic POMC neurons[J].Proceedings of the National Academy of Sciences of the United States of America,2008,105(28):9811-9816.  
[13] COLLEY D,CASTONGUAY T W.Effects of sugar solutions on hypothalamic appetite regulation[J].Physiology & Behavior,2015,139:202-209.
[14] 沈福良,施全林,王利文,等.高营养水平日粮添加葡萄糖对高温应激哺乳母猪繁殖性能和产仔性能的影响[J].中国饲料,2020(4):91-94.
[15] 杨久仙,张荣飞,马秋刚,等.葡萄糖氧化酶对断奶仔猪生长性能及肠道健康的影响[J].中国畜牧兽医,2011,38(6):18-21.
[16] 于娟,庄明,杨景晁,等.饮水添加葡萄糖氧化酶对肉鸡生产性能的影响[J].家禽科学,2019(4):25-8.
[17] SHAPIRO A,MU W,RONCAL C,et al.Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding[J].American Journal of Physiology:Regulatory,Integrative and Comparative Physiology,2008,295(5):R1370-R1375.
[18] LÊ K A,TAPPY L.Metabolic effects of fructose[J].Current Opinion in Clinical Nutrition and Metabolic Care,2006,9(4):469-475.  
[19] TEFF K L,ELLIOTT S S,TSCHÖP M,et al.Dietary fructose reduces circulating insulin and leptin,attenuates postprandial suppression of ghrelin,and increases triglycerides in women[J].The Journal of Clinical Endocrinology & Metabolism,2004,89(6):2963-2972.  
[20] JIAO G F,ZHANG G Z,WANG H Y,et al.Glucose intake alters expression of neuropeptides derived from proopiomelanocortin in the lateral hypothalamus and the nucleus accumbens in fructose preference rats[J].Neural Plasticity,2017,2017:1-7.
[21] 马红艳,姚毅,赵辉.日粮添加α-半乳糖苷酶对断奶仔猪生长性能、养分消化率、肠道形态和消化酶活力的影响[J].中国饲料,2018(14):66-70.
[22] 高木珍,王俊菊,史艳艳,等.α-半乳糖苷酶对肉鸡生产性能、表观消化率和肠道菌群的影响[J].天津农业科学,2020,26(2):58-61.
[23] BAE Y J,BAK Y K,KIM B,et al.Coconut-derived D-xylose affects postprandial glucose and insulin responses in healthy individuals[J].Nutrition Research and Practice,2011,5(6):533-539.  
[24] LIM E,LIM J Y,SHIN J H,et al.D-xylose suppresses adipogenesis and regulates lipid metabolism genes in high-fat diet-induced obese mice[J].Nutrition Research,2015,35(7):626-636.  
[25] 孟宪生.日粮中添加蔗糖饲喂生长肥育猪的增重效果[J].当代畜牧,2002(2):41-42.
[26] HIGGINS K A,MATTES R D.A randomized controlled trial contrasting the effects of 4 low-calorie sweeteners and sucrose on body weight in adults with overweight or obesity[J].The American Journal of Clinical Nutrition,2019,109(5):1288-1301.  
[27] VAN ENGELEN M,KHODABANDEH S,AKHAVAN T,et al.Effect of sugars in solutions on subjective appetite and short-term food intake in 9- to 14-year-old normal weight boys[J].European Journal of Clinical Nutrition,2014,68(7):773-777.  
[28] YIN K J,XIE D Y,ZHAO L,et al.Effects of different sweeteners on behavior and neurotransmitters release in mice[J].Journal of Food Science and Technology,2020,57(1):113-121.  
[29] TEY S L,SALLEH N B,HENRY J,et al.Effects of aspartame-,monk fruit-,stevia- and sucrose-sweetened beverages on postprandial glucose,insulin and energy intake[J].International Journal of Obesity,2017,41(3):450-457.  
[30] SØBERG S,SANDHOLT C H,JESPERSEN N Z,et al.FGF21 is a sugar-induced hormone associated with sweet intake and preference in humans[J].Cell Metabolism,2017,25(5):1045-1053.e6.  
[31] 吕路芳,谢文惠,姜宁,等.乳果糖生产方法及其在肉鸡生产中的应用[J].中国饲料,2018(19):15-19.
[32] ZHU C J,XU P W,HE Y L,et al.Heparin increases food intake through AgRP neurons[J].Cell Reports,2017,20(10):2455-2467.  
[33] YANG L S,WANG L N,ZHU C J,et al.Laminarin counteracts diet-induced obesity associated with glucagon-like peptide-1 secretion[J].Oncotarget,2017,8(59):99470-99481.  
[34] ZHAO F Q,LIU Q B,CAO J,et al.A sea cucumber (Holothuria leucospilota) polysaccharide improves the gut microbiome to alleviate the symptoms of type 2 diabetes mellitus in Goto-Kakizaki rats[J].Food and Chemical Toxicology,2020,135:110886.
[35] YU R Q,YIN Y X,CAO M K,et al.Fructo-oligosaccharides lower serum lipid levels and suppress high-fat/high-sugar diet-induced inflammation by elevating serum and gut levels of short-chain fatty acids[J/OL].The Journal of International Medical Research,2019,doi:10.1177/0300060519896714.
[36] 孙海清.母猪妊娠日粮中可溶性纤维调控泌乳期采食量的机制及改善母猪繁殖性能的作用[D].博士学位论文.武汉:华中农业大学,2013.
[37] COLANTUONI C,SCHWENKER J,MCCARTHY J,et al.Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain[J].Neuroreport,2001,12(16):3549-3552.  
[38] VAN OPSTAL A M,VAN DEN BERG-HUYSMANS A A,HOEKSMA M,et al.The effect of consumption temperature on the homeostatic and hedonic responses to glucose ingestion in the hypothalamus and the reward system[J].The American Journal of Clinical Nutrition,2018,107(1):20-25.  
[39] CHONG C P,SHAHAR S,HARON H,et al.Habitual sugar intake and cognitive impairment among multi-ethnic Malaysian older adults[J].Clinical Interventions in Aging,2019,(14):1331-1342.
[40] ROSS A P,BARTNESS T J,MIELKE J G,et al.A high fructose diet impairs spatial memory in male rats[J].Neurobiology of Learning and Memory,2009,92(3):410-416.  
[41] FRANCO-PÉREZ J,MANJARREZ-MARMOLEJO J,BALLESTEROS-ZEBADÚ A P,et al.Chronic consumption of fructose induces behavioral alterations by increasing orexin and dopamine levels in the rat brain[J].Nutrients,2018,10(11):1722.
[42] SCLAFANI A,ZUKERMAN S,ACKROFF K.Postoral glucose sensing,not caloric content,determines sugar reward in C57BL/6J mice[J].Chemical Senses,2015,40(4):245-258.  
[43] SMAIL-CREVIER R L,MARACLE A C,WASH S I J,et al.Binge-like intake of sucrose reduces the rewarding value of sucrose in adult rats[J].Physiology & Behavior,2018,194:420-429.
[44] KREISLER A D,MATTOCK M,ZORRILLA E P.The duration of intermittent access to preferred sucrose-rich food affects binge-like intake,fat accumulation,and fasting glucose in male rats[J].Appetite,2018,130:59-69.
[45] TENK C M,FELFELI T.Sucrose and fat content significantly affects palatable food consumption in adolescent male and female rats[J].Appetite,2017,118:49-59.
[46] BLANCAS-VELAZQUEZ A S,UNMEHOPA U A,EGGELS L,et al.A free-choice high-fat high-sugar diet alters day-night Per2 gene expression in reward-related brain areas in rats[J].Frontiers in Endocrinology,2018,9:154.
[47] AVENA N M,RADA R,HOEBEL B G.Underweight rats have enhanced dopamine release and blunted acetylcholine response in the nucleus accumbens while bingeing on sucrose[J].Neuroscience,2008,156(4):865-871.  
[48] RORABAUGH J M,STRATFORD J M,ZAHNISER N R.Differences in bingeing behavior and cocaine reward following intermittent access to sucrose,glucose or fructose solutions[J].Neuroscience,2015,301:213-220.
[49] WANG J W,LI Y X,LUO P,et al.Oral supplementation with ginseng polysaccharide promotes food intake in mice[J].Brain and Behavior,2019,9(9):e1340.
[50] LOW Y,LACY K,KEAST R.The role of sweet taste in satiation and satiety[J].Nutrients,2014,6(9):3431-3450.  
[51] HAJNAL A,SMITH G P,NORGREN R.Oral sucrose stimulation increases accumbens dopamine in the rat[J].American Journal of Physiology:Regulatory,Integrative and Comparative Physiology,2004,286(1):R31-R37.
文章导航

/