动物营养学报 >

2021 , Vol. 33 >Issue 2: 1055 - 1062

DOI: https://doi.org/10.3969/j.issn.1006-267x.2021.02.045

特种经济动物营养与饲料 SPECIAL ECONOMIC ANIMAL NUTRITION AND FEED

乳酸锌对断奶肉兔生长性能、肠道发育和血清生化指标的影响

  • 俞成浩 ,
  • 郭志强 ,
  • 雷岷 ,
  • 李丛艳 ,
  • 任永军 ,
  • 郑洁 ,
  • 梅秀丽 ,
  • 杨锐 ,
  • 谢晓红 ,
  • 邝良德
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  • 1. 四川省畜牧科学研究院, 成都 610066;
    2. 西南民族大学生命科学与技术学院, 成都 610041;
    3. 四川省动物遗传育种重点实验室, 成都 610066
俞成浩(1996-),男,安徽马鞍山人,硕士研究生,研究方向为家兔繁殖与饲养。E-mail:879928402@qq.com

收稿日期: 2020-07-27

  网络出版日期: 2021-02-04

基金资助

肉兔健康养殖关键技术集成示范与推广应用（2019JDZH002）；国家兔产业技术体系项目（CARS-43-D-3）；四川省重点研发项目（2018NZ0137）；四川白兔优良种质资源扩繁与健康养殖技术示范推广（2020JDZH0029）；肉兔配套系培育及配套技术研究与示范（SASA2020CZYX004）；优质肉兔配套系选育及配套技术研究与示范（2016NYZ0046）

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Effects of Zinc Lactate on Growth Performance, Intestinal Development and Serum Biochemical Indexes of Weaned Rabbits

  • YU Chenghao ,
  • GUO Zhiqiang ,
  • LEI Min ,
  • LI Congyan ,
  • REN Yongjun ,
  • ZHENG Jie ,
  • MEI Xiuli ,
  • YANG Rui ,
  • XIE Xiaohong ,
  • KUANG Liangde
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  • 1. Sichuan Animal Science Academy, Chengdu 610066, China;
    2. College of Life Science and Technology, Southwest Minzu University, Chengdu 610041, China;
    3. Genetics Key Laboratory of Sichuan Province, Chengdu 610066, China

Received date: 2020-07-27

  Online published: 2021-02-04

Supported by

 

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摘要

本试验旨在研究饲粮中添加乳酸锌对断奶肉兔生长性能、肠道发育和血清生化指标的影响。选择28日龄同期断奶新西兰兔420只，随机分为5组：对照组（饲喂基础饲粮，饲粮中添加硫酸锌形式的锌0 mg/kg）、硫酸锌组（在基础饲粮中添加硫酸锌形式的锌80 mg/kg）以及3个乳酸锌组（在基础饲粮中分别添加乳酸锌形式的锌20、40、80 mg/kg），每组14个重复，每个重复6只（公母各占1/2）。预试期7 d，正试期42 d。结果表明：1）与对照组相比，饲粮中添加40和80 mg/kg乳酸锌可以显著提高断奶肉兔的试验末重和平均日增重（P<0.05），显著降低料重比、腹泻率和死亡率（P<0.05），但对平均日采食量无显著影响（P>0.05）；40 mg/kg乳酸锌组肉兔的试验末重、平均日增重和料重比与硫酸锌组差异不显著（P>0.05），但腹泻率和死亡率较低。2）与对照组相比，饲粮中添加40和80 mg/kg乳酸锌可以显著提高断奶肉兔小肠绒毛高度和绒毛高度/隐窝深度（P<0.05），显著降低十二指肠隐窝深度（P<0.05）；80 mg/kg乳酸锌组肉兔十二指肠绒毛高度显著高于同水平硫酸锌组（P<0.05）。3）与对照组相比，饲粮中添加40和80 mg/kg乳酸锌可以显著提高断奶肉兔血清抗氧化酶活性及生长激素和胰岛素样生长因子-Ⅰ含量（P<0.05）；40 mg/kg乳酸锌组肉兔血清生化指标与硫酸锌组差异不显著（P>0.05），80 mg/kg乳酸锌组在提高肉兔血清铜锌超氧化物歧化酶活性和生长激素含量方面优于同水平硫酸锌组。综上所述，饲粮中添加乳酸锌可以促进肉兔生长、降低腹泻率和死亡率、改善血清生化指标和肠道发育；乳酸锌的添加效果显著优于相同水平的硫酸锌，养兔生产中乳酸锌适宜添加水平为40 mg/kg。

关键词： 乳酸锌; 断奶肉兔; 肠道发育; 血清生化指标

本文引用格式

俞成浩 , 郭志强 , 雷岷 , 李丛艳 , 任永军 , 郑洁 , 梅秀丽 , 杨锐 , 谢晓红 , 邝良德 . 乳酸锌对断奶肉兔生长性能、肠道发育和血清生化指标的影响[J]. 动物营养学报, 2021 , 33(2) : 1055 -1062 . DOI: 10.3969/j.issn.1006-267x.2021.02.045

Abstract

The purpose of this experiment was to study the effects of zinc lactate on growth performance, intestinal development and serum biochemical indexes of weaned rabbits. In the experiment, 420 weaned New Zealand rabbits at 28 days of age were randomly divided into 5 group: control group (fed a basal diet supplemented with 0 mg/kg zinc sulfate), zinc sulfate group (fed the basal diet supplemented with 80 mg/kg zinc sulfate) and three zinc lactate groups (fed the basal diet supplemented with 20, 40 and 80 mg/kg zinc lactate, respectively), and each group had 14 replicates with 6 rabbits (half male and half female) per replicate. The pre-experimental period lasted for 7 days,and the experimental period lasted for 42 days.The results showed as follows: 1) compared with control group, the diet supplemented with 40 and 80 mg/kg zinc lactate significantly increased the final body weight and average daily gain of weaned rabbits (P<0.05), decreased the feed to weight ratio, diarrhea rate and mortality (P<0.05), but had no significant effect on the average daily intake (P>0.05); the final body weight, average daily gain and feed to weight ratio of 40 mg/kg zinc lactate group was not different from zinc sulfate group (P>0.05), but diarrhea rate and mortality were lower. 2) Compared with control group, adding 40 and 80 mg/kg zinc lactate to the diet could significantly increase the villus height and villus height/crypt depth of small intestine (P<0.05), and significantly decrease the depth of duodenal crypt (P<0.05); the height of duodenal villus in 80 mg/kg zinc lactate group was significantly higher than that in the same level zinc sulfate group (P<0.05). 3) Compared with control group, adding 40 and 80 mg/kg zinc lactate to the diet could significantly improve the serum antioxidant enzyme activity, growth hormone and insulin-like growth factor-Ⅰ contents of weaned rabbits (P<0.05); the serum biochemical indexes in 40 mg/kg zinc lactate group were not different from those in zinc sulfate group (P>0.05), and 80 mg/kg zinc lactate group was superior to the same level zinc sulfate group in improving the serum copper zinc superoxide dismutase activity and growth hormone content of weaned rabbits. Therefore, zinc lactate added to the diet can promote the growth of meat rabbits, reduce the diarrhea rate and mortality rate, improve serum biochemical indexes and intestinal development; the effects of zinc lactate added is significantly better than that of zinc sulfate at the same level, and the appropriate amounts of zinc lactate in diet is 40 mg/kg in rabbit production.

Key words： zinc lactate; weaned rabbit; intestinal development; serum biochemical indexes

参考文献

[1] NAYERI A,UPAH N C,SUCU E,et al.Effect of the ratio of zinc amino acid complex to zinc sulfate on the performance of Holstein cows[J].Journal of Dairy Science,2014,97(7):4392-4404.  
[2] 白国勇.乳酸锌的研究进展及在兔营养中的应用[J].四川畜牧兽医,2007,34(8):34-35. BAI G Y.Research progress of zinc lactate and its application in the nutrient of rabbits[J].Sichuan Animal Husbandry and veterinary,2007,34(8):34-35.(in Chinese)
[3] 杨翠军,葛剑,吴淑琴.日粮锌水平对生长期獭兔生长性能和血清生化指标的影响[J].中国养兔,2019,2(1):4-7. YANG C J,GE J,WU S Q.Effects of dietary zinc supplemental level on growth performance and serum biochemical indexes of growing Rex rabbits[J].Chinese Journal of Rabbit Farming,2019,2(1):4-7.(in Chinese)
[4] 杨国雨,刘公言,陈晓阳,等.饲粮锌添加水平对生长獭兔生长性能、屠宰性能、肌肉品质、毛皮质量及氮代谢的影响[J].动物营养学报,2019,31(4):1936-1942. YANG G Y,LIU G Y,CHEN X Y,et al.Effects of dietary zinc supplemental level on growth performance,slaughter performance, meat quality, fur quality and nitrogen metabolism of growing Rex rabbits[J].Chinese Journal of Animal Nutrition,2019,31(4):1936-1942.(in Chinese)
[5] 任战军,白彦,李发弟.不同锌源及水平对幼龄艾哥兔生长性能与组织锌沉积的影响[J].草业学报,2014,23(1):283-290. REN Z J,BAI Y,LI F D.Effects of different sources and levels of zinc on growth performance and tissue zinc accumulation of the young Elco rabbit[J].Acta Prataculturae Sinica,2014,23(1):283-290.(in Chinese)
[6] WANG C,ZHANG L G,YING Z X,et al.Effects of dietary zinc oxide nanoparticles on growth,diarrhea,mineral deposition,intestinal morphology,and barrier of weaned piglets[J].Biological Trace Element Research,2018,185(2):364-374.  
[7] ZHANG H B,WANG M S,WANG Z S,et al.Supplementation dietary zinc levels on growth performance,carcass traits,and intramuscular fat deposition in weaned piglets[J].Biological Trace Element Research,2014,161(1):69-77.  
[8] 张斌,刘磊,李福昌.家兔饲料和营养需要量研究进展[J].中国兽医学报,2018,38(11):2234-2240. ZHANG B,LIU L,LI F C.The research progress of rabbit dietary nutrition and requirement[J].Chinese Journal of Veterinary Science,2018,38(11):2234-2240.(in Chinese)
[9] CUI H,ZHANG T T,NIE H,et al.Effects of sources and concentrations of zinc on growth performance,nutrient digestibility,and fur quality of growing-furring female mink (Mustela vison)[J].Journal of Animal Science,2017,95(12):5420-5429.  
[10] SUN J Y,WANG J F,ZI N T,et al.Effects of zinc supplementation and deficiency on bone metabolism and related gene expression in rat[J].Biological Trace Element Research,2011,143(1):394-402.  
[11] KREBS N F.Overview of zinc absorption and excretion in the human gastrointestinal tract[J].The Journal of Nutrition,2000,130(5):1374S-1377S.
[12] LI B T,VAN KESSEL A G,CAINE W R,et al.Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide[J].Canadian Journal of Animal Science,2001,81(4):511-516.  
[13] ZHU C,LV H,CHEN Z,et al.Dietary zinc oxide modulates antioxidant capacity,small intestine development,and jejunal gene expression in weaned piglets[J].Biological Trace Element Research,2017,175(2):331-338.  
[14] HU C H,GU L Y,LUAN Z S,et al.Effects of montmorillonite-zinc oxide hybrid on performance,diarrhea,intestinal permeability and morphology of weanling pigs[J].Animal Feed Science and Technology,2012,177(1/2):108-115.
[15] SHAO Y X,LEI Z,YUAN J M,et al.Effect of zinc on growth performance,gut morphometry,and cecal microbial community in broilers challenged with Salmonella enterica serovar typhimurium[J].Journal of Microbiology,2014,52(12):1002-1011.  
[16] PRASAD A S.Discovery of human zinc deficiency and studies in an experimental human model[J].The American Journal of Clinical Nutrition,1991,53(2):403-412.  
[17] KARA E,GUNAY M,CICIOGLU Ī,et al.Effect of zinc supplementation on antioxidant activity in young wrestlers[J].Biological Trace Element Research,2010,134(1):55-63.  
[18] MA W Q,NIU H H,FENG J,et al.Effects of zinc glycine chelate on oxidative stress,contents of trace elements,and intestinal morphology in broilers[J].Biological Trace Element Research,2011,142(3):546-556.  
[19] 张彩英,曹华斌,胡国良,等.日粮高锌对断奶仔猪某些血清生化指标的影响[J].黑龙江畜牧兽医,2013(10):65-67. ZHANG C Y,CAO H B,HU G L,et al.Effects of high zinc on certain serum biochemical indexes of weaned piglets[J].Heilongjiang Animal Husbandry and Veterinary,2013(10):65-67.(in Chinese)
[20] TAPIERO H,TEW K D.Trace elements in human physiology and pathology:zinc and metallothioneins[J].Biomedicine & Pharmacotherapy,2003,57(9):399-411.  
[21] NAGALAKSHMI D,SRIDHAR K,PARASHURAMULU S.Replacement of inorganic zinc with lower levels of organic zinc (zinc nicotinate) on performance,hematological and serum biochemical constituents,antioxidants status,and immune responses in rats[J].Veterinary World,2015,8(9):1156-1162.  
[22] NINH N X,THISSEN J P,MAITER D,et al.Reduced liver insulin-like growth factor-Ⅰ gene expression in young zinc-deprived rats is associated with a decrease in liver growth hormone (GH) receptors and serum GH-binding protein[J].Journal of Endocrinology,1995,144(3):449-456.  
[23] MACDONALD R S.The role of zinc in growth and cell proliferation[J].The Journal of Nutrition,2000,130(5S Suppl.):1500S-1508S.
[24] CESUR Y,YORDAM N,DOĞAN M.Serum insulin-like growth factor-Ⅰ and insulin-like growth factor binding protein-3 levels in children with zinc deficiency and the effect of zinc supplementation on these parameters[J].Journal of Pediatric Endocrinology and Metabolism,2009,22(12):1137-1143.
[25] NINH N X,MAITER D,VERNIERS J,et al.Failure of exogenous IGF-Ⅰ to restore normal growth in rats submitted to dietary zinc deprivation[J].Journal of Endocrinology,1998,159(2):211-217.  
[26] 朱宇旌,王浩然,李方方,等.半胱胺螯合锌对仔猪生长性能、血清生化指标、养分消化率及粪中微生物菌群的影响[J].动物营养学报,2015,27(10):3225-3232. ZHU Y J,WANG H R,LI F F,et al.Effects of cysteamine chelated zinc on growth performance,serum biochemical indices, nutrient digestibility and fecal microbial flora of piglets[J].Chinese Journal of Animal Nutrition,2015,27(10):3225-3232.(in Chinese)
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