综述 REVIEW

非编码RNAs在肉牛肌肉发育和脂肪沉积中的研究进展

  • 曾斌 ,
  • 高骞 ,
  • 沈维军 ,
  • 万发春
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  • 湖南农业大学动物科学技术学院, 长沙 410128
曾斌(1991-),男,湖南永州人,博士,从事反刍动物营养调控研究。E-mail:zengbinyx@163.com

收稿日期: 2021-03-07

  网络出版日期: 2021-09-18

基金资助

国家肉牛牦牛产业技术体系(CARS-37);国家自然科学基金项目(31772633)

Research Progress of Non-Coding RNAs in Muscle Development and Fat Deposition in Beef Cattle

  • ZENG Bin ,
  • GAO Qian ,
  • SHEN Weijun ,
  • WAN Fachun
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  • College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China

Received date: 2021-03-07

  Online published: 2021-09-18

Supported by

 

摘要

肌肉和脂肪作为动物机体的主要组成部分,同时是畜牧生产中重要的经济性状。动物肌肉发育和脂肪沉积都是复杂的生物学过程,受到严密而精确的调控。近年来研究表明,非编码RNAs作为一类调节因子,在肌肉发育和脂肪沉积过程中发挥重要调控作用。牛肉是我国主要的肉类来源之一。肉牛肌肉发育和脂肪沉积过程与牛肉产量和牛肉品质密切相关。本文在简要概括肉牛肌肉发育、脂肪沉积过程和非编码RNAs作用机制的基础上,详细总结了非编码RNAs(微小RNA、长链非编码RNA和环状RNA)在肉牛肌肉发育和脂肪沉积中的最新生物学功能研究进展,并对非编码RNAs在肉牛肌肉发育和脂肪沉积中的研究进行展望,以期为今后非编码RNAs在肉牛营养调控和分子育种方面的研究提供科学理论依据和参考。

本文引用格式

曾斌 , 高骞 , 沈维军 , 万发春 . 非编码RNAs在肉牛肌肉发育和脂肪沉积中的研究进展[J]. 动物营养学报, 2021 , 33(9) : 4827 -4838 . DOI: 10.3969/j.issn.1006-267x.2021.09.004

Abstract

As the main components of animal body, muscle and fat are important economic traits in animal husbandry. Muscle development and fat deposition in animals are complex biological processes, which are strictly and precisely regulated. Recent studies have shown that non-coding RNAs, as a class of regulatory factors, play an important regulatory role in muscle development and fat deposition. Beef is one of the main meat sources in our country. The process of muscle development and fat deposition in beef cattle is closely related to the yield and quality of beef. This review briefly summarized the process of muscle development and fat deposition in beef cattle and non-coding RNAs mechanism, detail summarized the biological functions of non-coding RNAs (microRNA, long non-coding RNAs and circRNAs) in muscle development and fat deposition of beef cattle, and put forward the research prospects of non-coding RNAs in muscle development and fat deposition in beef cattle, in order to provide a scientific basis and reference for the future research of non-coding RNAs in nutritional regulation and molecular breeding of beef cattle.

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