[1] 彭丹,郭贺,杨嘉盛.不同产地水飞蓟籽油理化特性及脂肪酸组成比较[J].河南工业大学学报(自然科学版),2020,41(1):8-12. PENG D,GUO H,YANG J S.Comparison of physicochemical properties and fatty acid composition of
Silybum marianum seed oils from different regions[J].Journal of Henan University of Technology (Natural Science Edition),2020,41(1):8-12.(in Chinese)
[2] 马星海.水飞蓟化学成分和药理作用研究进展[J].亚太传统医药,2015,11(19):62-65. MA X H.Progress in the chemical composition and pharmacological activity of
Silybum marianum[J].Asia-Pacific Traditional Medicine,2015,11(19):62-65.(in Chinese)
[3] KREN V,WALTEROVÁ D.Silybin and silymarin-new effects and applications[J].Biomedical Papers of the Medical Faculty of the University Palacky,Olomouc,Czechoslovakia,2005,149(1):29-41.
[4] BIJAK M.Silybin,a major bioactive component of milk thistle (
Silybum marianum L. Gaernt.) chemistry,bioavailability,and metabolism[J].Molecules,2017,22(11):1942.
[5] WIANOWSKA D,WIŚNIEWSKI M.Simplified procedure of silymarin extraction from
Silybum marianum L. Gaertner[J].Journal of Chromatographic Science,2015,53(2):366-372.
[6] 隋博.水飞蓟籽的亚临界萃取工艺及籽粕品质研究[D].硕士学位论文.郑州:郑州大学,2018. SUI B.Study on
Silybum marianum extraction by subcritical extraction technology and the quality of seed meal[D].Master's Thesis.Zhengzhou:Zhengzhou University,2018.(in Chinese)
[7] SAHIN E,BAGCI R,BEKTUR AYKANAT N E,et al.Silymarin attenuated nonalcoholic fatty liver disease through the regulation of endoplasmic reticulum stress proteins GRP78 and XBP-1 in mice[J].Journal of Food Biochemistry,2020,44(6):e13194.
[8] YUN D G,LEE D G.Silymarin exerts antifungal effects via membrane-targeted mode of action by increasing permeability and inducing oxidative stress[J].Biochimica et Biophysica Acta:Biomembranes,2017,1859(3):467-474.
[9] XIAO P,JI H,YE Y T,et al.Dietary silymarin supplementation promotes growth performance and improves lipid metabolism and health status in grass carp (
Ctenopharyngodon idellus) fed diets with elevated lipid levels[J].Fish Physiology and Biochemistry,2017,43(1):245-263.
[10] ABOELWAFA H R,EL-KOTT A F,ABD-ELLA E M,et al.The possible neuroprotective effect of silymarin against aluminum chloride-prompted Alzheimer's-like disease in rats[J].Brain Sciences,2020,10(9):628.
[11] 苟庚午,蒋明,文华,等.饲料中添加水飞蓟素对吉富罗非鱼生长性能、肝脏脂肪代谢酶和抗氧化能力的影响[J].水产学报,2016,40(9):1309-1320. GOU G W,JIANG M,WEN H,et al.Effects of dietary silymarin on growth performance,enzymes of hepatic lipid metabolism and antioxidant ability in GIFT
Oreochromis niloticus[J].Journal of Fisheries of China,2016,40(9):1309-1320.(in Chinese)
[12] PEBRIANSYAH A,LUKEŠOVÁ D,KNÍŽKOVÁ I,et al.The effect of natural phytoadditive
Silybum marianum on performance of broiler rabbits[J].Scientia Agriculturae Bohemica,2019,50(1):40-45.
[13] STASTNIK O,PAVLATA L,MRKVICOVA E.The milk thistle seed cakes and hempseed cakes are potential feed for poultry[J].Animals,2020,10(8):1384.
[14] GILLESSEN A,SCHMIDT H H J.Silymarin as supportive treatment in liver diseases:a narrative review[J].Advances in Therapy,2020,37(4):1279-1301.
[15] FAN L,MA Y L,LIU Y,et al.Silymarin induces cell cycle arrest and apoptosis in ovarian cancer cells[J].European Journal of Pharmacology,2014,743:79-88.
[16] DE MARCO A,LUONGO G,DI MARINO C,et al.Silymarin from
Silybum marianum by Naviglio's extractor:a new and very efficient approach[J/OL].Natural Product Research,2019:1-7.(2019-11-06)[2021-02-25].https://pubmed.ncbi.nlm.nih.gov/31691591/.DOI:10.1080/14786419.2019.1687474.
[17] GONZÁLEZ L T,MINSKY N W,ESPINOSA L E M,et al.
In vitro assessment of hepatoprotective agents against damage induced by acetaminophen and CCl
4[J].BMC Complementary and Alternative Medicine,2017,17(1):39.
[18] WU J P,TSAI C C,YEH Y L,et al.Silymarin accelerates liver regeneration after partial hepatectomy[J].Evidence-based Complementary and Alternative Medicine,2015,2015:603529.
[19] 李爱云.水飞蓟油对脂肪肝干预的初步研究[J].中南药学,2017,15(2):175-177. LI A Y.Therapeutic effect of
Silybum marianum oil on fatty liver disease[J].Central South Pharmacy,2017,15(2):175-177.(in Chinese)
[20] LUSHCHAK V I.Free radicals,reactive oxygen species,oxidative stress and its classification[J].Chemico-Biological Interactions,2014,224:164-175.
[21] NIKI E.Biomarkers of lipid peroxidation in clinical material[J].Biochimica et Biophysica Acta:General Subjects,2014,1840(2):809-817.
[22] ADEMOWO O S,DIAS H K I,BURTON D G A,et al.Lipid (per) oxidation in mitochondria:an emerging target in the ageing process?[J].Biogerontology,2017,18(6):859-879.
[23] MACDONALD-RAMOS K,MICHÁN L,MARTÍNEZ-IBARRA A,et al.Silymarin is an ally against insulin resistance:a review[J].Annals of Hepatology,2020,23:100255.
[24] DARVISHI-KHEZRI H,SALEHIFAR E,KOSARYAN M,et al.Iron-chelating effect of silymarin in patients with β-thalassemia major:a crossover randomised control trial[J].Phytotherapy Research,2018,32(3):496-503.
[25] SURAI P F.Silymarin as a natural antioxidant:an overview of the current evidence and perspectives[J].Antioxidants,2015,4(1):204-247.
[26] SAMANTA R,PATTNAIK A K,PRADHAN K K,et al.Wound healing activity of silibinin in mice[J].Pharmacognosy Research,2016,8(4):298-302.
[27] 胡思琪,邓谷霖,李华,等.卡托普利与水飞蓟宾联用对大鼠酒精性脂肪肝的作用及抗氧化应激机制[J].中药药理与临床,2019,35(4):100-102. HU S Q,DENG G L,LI H,et al.The effect of captopril and silybin on the alcoholic fatty liver and the mechanism of antioxidant stress in rats[J].Pharmacology and Clinics of Chinese Materia Medica,2019,35(4):100-102.(in Chinese)
[28] 荣家闵,于明,葛雅琨,等.水飞蓟宾对H
2O
2诱导SH-SY5Y细胞损伤的保护作用及机制[J].南京医科大学学报(自然科学版),2020,40(4):515-520. RONG J M,YU M,GE Y K,et al.Protective effects and mechanism of silibinin on SH-SY5Y cell injury induced by hydrogen peroxide[J].Journal of Nanjing Medical University (Natural Sciences Edition),2020,40(4):515-520.(in Chinese)
[29] 秦帅,吴丽丽,秦灵灵,等.水飞蓟宾对C2C12细胞胰岛素抵抗的影响及机制研究[J].世界科学技术-中医药现代化,2020,22(10):3450-3455. QIN S,WU L L,QIN L L,et al.Study on effects and mechanisms of silybin on insulin resistance of C2C12 cells[J].Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology,2020,22(10):3450-3455.(in Chinese)
[30] 邵飞,金露,沈山梅,等.水飞蓟素对多囊卵巢综合征模型大鼠炎症因子、纤维化指标及性激素水平的影响[J].现代中西医结合杂志,2019,28(26):2855-2859,2877. SHAO F,JIN L,SHEN S M,et al.Effects of silymarin on inflammatory factors,fibrosis markers and sex hormone levels in rats with polycystic ovary syndrome[J].Modern Journal of Integrated Traditional Chinese and Western Medicine,2019,28(26):2855-2859,2877.(in Chinese)
[31] UMETSU T,INOUE J,KOGURE T,et al.Inhibitory effect of silibinin on hepatitis B virus entry[J].Biochemistry and Biophysics Reports,2018,14:20-25.
[32] TAN J,HU J P,HE Y H,et al.Retraction note:protective role of silymarin in a mouse model of renal ischemia-reperfusion injury[J].Diagnostic Pathology,2018,13:71.
[33] ZHANG B L,XU D,SHE L L,et al.Silybin inhibits NLRP3 inflammasome assembly through the NAD
+/SIRT2 pathway in mice with nonalcoholic fatty liver disease[J].The FASEB Journal,2018,32(2):757-767.
[34] 罗颂,张羽,何彦瑶,等.水飞蓟宾通过调控AMPK活性抑制自由脂肪酸诱导的肝细胞炎症因子分泌[J].西北药学杂志,2019,34(1):72-75. LUO S,ZHANG Y,HE Y Y,et al.Silybin inhibits inflammatory cytokine secretion of hepatocytes induced by free fatty acid through regulating AMPK activity[J].Northwest Pharmaceutical Journal,2019,34(1):72-75.(in Chinese)
[35] CHANG K J,LIN J A,CHEN S Y,et al.Silymarin protects against high fat diet-evoked metabolic injury by induction of glucagon-like peptide 1 and sirtuin 1[J].Journal of Functional Foods,2019,56:136-144.
[36] BAGCI R,SAHINTURK V,SAHIN E.Azoramide ameliorates fructose-induced nonalcoholic fatty liver disease in mice[J].Tissue & Cell,2019,59:62-69.
[37] 高华武,陈明,龙子江,等.水飞蓟宾对高脂诱导非酒精性脂肪肝大鼠的调脂保肝作用[J].药物评价研究,2017,40(6):773-777. GAO H W,CHEN M,LONG Z J,et al.Lipid hepatoprotective effect of silibinin on fat-induced nonalcoholic fatty liver rat model[J].Drug Evaluation Research,2017,40(6):773-777.(in Chinese)
[38] SUH H J,CHO S Y,KIM E Y,et al.Blockade of lipid accumulation by silibinin in adipocytes and zebrafish[J].Chemico-Biological Interactions,2015,227:53-62.
[39] JIANG X,LIN S,LIN Y,et al.Effects of silymarin supplementation during transition and lactation on reproductive performance,milk composition and haematological parameters in sows[J].Journal of Animal Physiology and Animal Nutrition,2020,104(6):1896-1903.
[40] FARMER C,LAPOINTE J,PALIN M F.Effects of the plant extract silymarin on prolactin concentrations,mammary gland development,and oxidative stress in gestating gilts[J].Journal of Animal Science,2014,92(7):2922-2930.
[41] GRELA E R,ŚWIATKIEWICZ M,FLOREK M,et al.Impact of milk thistle (
Silybum marianum L.) seeds in fattener diets on pig performance and carcass traits and fatty acid profile and cholesterol of meat,backfat and liver[J].Livestock Science,2020,239:104180.
[42] ZAREI A,MOROVAT M,CHAMANI M,et al.Effect of
in ovo feeding and dietary feeding of
Silybum marianum extract on performance,immunity and blood cation-anion balance of broiler chickens exposed to high temperatures[J].Iranian Journal of Applied Animal Science,2016,6(3):697-705.
[43] JAHANIAN E,MAHDAVI A H,ASGARY S,et al.Effects of dietary inclusion of silymarin on performance,intestinal morphology and ileal bacterial count in aflatoxin-challenged broiler chicks[J].Journal of Animal Physiology and Animal Nutrition,2017,101(5):e43-e54.
[44] NIK H A,MAKKI O F,EBRAHIMZADEH A,et al.Evaluation of blood chemical,lipids profile and immune response on broiler chicks fed with milk thistle (
Silybum marianum L.) and thyme (
Thymus vulgaris L.) seeds in south-eastern Iran[J].Veterinary Science Development,2015,5(1):5621.
[45] RADKO L,CYBULSKI W.The decrease of lasalocid residue in the edible tissues by silymarin supplementation of chicken diet[J].Food Additives & Contaminants:Part A,2019,36(5):722-728.
[46] AHMAD M,CHAND N,KHAN R U,et al.Dietary supplementation of milk thistle (
Silybum marianum):growth performance,oxidative stress,and immune response in natural summer stressed broilers[J].Tropical Animal Health and Production,2020,52(2):711-715.
[47] ABOU S M,HAMED S,KHALIFAH M M,et al.Effect of silymarin supplementation on the performance of developed chickens under summer condition[J].Egyptian Poultry Science,2016,36:1233-124.
[48] WANG J Y,ZHOU H H,WANG X,et al.Effects of silymarin on growth performance,antioxidant capacity and immune response in turbot (
Scophthalmus maximus L.)[J].Journal of the World Aquaculture Society,2019,50:1168-1181.
[49] WEI L,WU P,ZHOU X Q,et al.Dietary silymarin supplementation enhanced growth performance and improved intestinal apical junctional complex on juvenile grass carp (
Ctenopharyngodon idella)[J].Aquaculture,2020,525:735311.
[50] OWATARI M S,ALVES JESUS G F,BRUM A,et al.Sylimarin as hepatic protector and immunomodulator in Nile tilapia during
Streptococcus agalactiae infection[J].Fish & Shellfish Immunology,2018,82:565-572.
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