综述 REVIEW

富勒烯[C60]抗氧化应激的研究进展及在畜禽生产中的应用前景

  • 刘广 ,
  • 罗友谊 ,
  • 唐宇龙 ,
  • 印遇龙
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  • 1. 湖南农业大学动物科学与技术学院, 长沙 410125;
    2. 中国科学院亚热带农业生态研究所, 中国科学院亚热带农业生态过程重点实验室, 湖南省畜禽健康养殖工程技术中心, 农业部中南动物营养与饲料科学观测实验站, 长沙 410125;
    3. 湖南省沅江市畜牧水产事务中心, 益阳 413100
刘广(1998-),男,湖南益阳人,硕士研究生,畜牧专业。E-mail:lg19980905@163.com

收稿日期: 2021-06-22

  网络出版日期: 2022-01-18

基金资助

湖南省科技支撑计划(2019RS3021);湖南省科技支撑计划(2019NK2161,2019NK2171);动物营养生理与代谢过程湖南省重点实验室(ISA2020212);广西自然科学基金(2020JJA130108);畜禽产品安全工程安徽省重点实验室(XM2003)

Research Progress on Antioxidant Stress of Fullerenes[C60] and Its Application Prospect in Livestock and Poultry Production

  • LIU Guang ,
  • LUO Youyi ,
  • TANG Yulong ,
  • YIN Yulong
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  • 1. College of Animal Science, Hunan Agricultural University, Changsha 410125, China;
    2. Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South Central, Ministry of Agriculture, Provincial Engineering Research Center of Healthy Livestock, Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;
    3. Animal Husbandry and Aquatic Products Affairs Center of Hunan Province Yuanjiang, Yiyang 413100, China

Received date: 2021-06-22

  Online published: 2022-01-18

摘要

氧化应激损伤是指机体在遭受有害刺激时,体内高活性分子,如活性氧自由基(ROS)或活性氮自由基(RNS)产生过多,导致细胞、组织和动物机体受到严重损伤。畜禽在应激和疾病的条件下会造成氧化应激并引发各种炎症。减少氧化应激以提高畜禽生长性能、减少疾病发病率是畜禽生产中的重要研究内容。近年来,富勒烯[C60]被认为是一种强大的抗氧化剂,大量研究表明富勒烯[C60]及其衍生物在自由基清除和缓解机体氧化应激反应中发挥重要作用。本文对富勒烯[C60]及其衍生物的抗氧化作用和机制进行归纳总结,旨在为畜禽生产中抗氧化剂和抗生素替代物的开发利用找到新的方向,使富勒烯能应用到畜禽生产以代替抗生素解决食品安全问题,更好地发展绿色、健康、安全的养殖业。

本文引用格式

刘广 , 罗友谊 , 唐宇龙 , 印遇龙 . 富勒烯[C60]抗氧化应激的研究进展及在畜禽生产中的应用前景[J]. 动物营养学报, 2022 , 34(1) : 59 -67 . DOI: 10.3969/j.issn.1006-267x.2022.01.007

Abstract

Oxidative stress injury refers to the excessive production of extremely reactive molecules within the body, like reactive oxygen species (ROS) or reactive nitrogen species (RNS), once the body is subjected to harmful stimuli, it causes serious harm to cells, tissues and animal's body. Livestock and poultry under stress and disease conditions can cause oxidative stress and various types of inflammation. Reducing oxidative stress is an important research component in livestock production to improve animal performance and reduce disease incidence. In recent years, fullerene is considered to be a powerful antioxidant, and numerous studies have shown that the fullerene[C60] and its derivatives play an important role in free radical scavenging and alleviation of oxidative stress in the body. In this paper, the antioxidant effect and mechanism of fullerene[C60] and its derivatives were summarized, to find a new direction for the development and utilization of antioxidants and antibiotic substitutes in animal production. The application of fullerene to livestock and poultry production can replace antibiotics to solve food safety problems, and can better develop the green, healthy and safe breeding industries.

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