施羽露 , 杨晓曦 , 郑尧 , 裘丽萍 , 胡庚东 , 邴旭文 , 陈家长 . 白藜芦醇对红罗非鱼肠道组织学和炎症因子含量的影响[J]. 动物营养学报, 2022 , 34(1) : 589 -599 . DOI: 10.3969/j.issn.1006-267x.2022.01.054

[1] KORTMAN G A M,MULDER M L M,RICHTERS T J W,et al.Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens[J].European Journal of Immunology,2015,45(9):2553-2567.  
[2] 呙于明,刘丹,张炳坤.家禽肠道屏障功能及其营养调节[C]//中国畜牧兽医学会动物营养学分会第七届中国饲料营养学术研讨会论文集.郑州:[s.n],2014:363. GOU Y M,LIU D,ZHANG B K,et al.Intestinal barrier function and nutritional regulation in poultry[C]//The Seventh Chinese Symposium on Feed Nutrition,Animal Nutrition Branch of Chinese Animal Husbandry and Veterinary Association.Zhengzhou:[s.n],2014:363.(in Chinese)
[3] PARK E J,PEZZUTO J M.The pharmacology of resveratrol in animals and humans[J].Biochimica et Biophysica Acta,2015,1852(6):1071-1113.  
[4] MAGYAR K,HALMOSI R,PALFI A,et al.Cardioprotection by resveratrol:a human clinical trial in patients with stable coronary artery disease[J].Clinical Hemorheology and Microcirculation,2012,50(3):179-187.  
[5] BO S,CICCONE G,CASTIGLIONE A,et al.Anti-inflammatory and antioxidant effects of resveratrol in healthy smokers a randomized,double-blind,placebo-controlled,cross-over trial[J].Current Medicinal Chemistry,2013,20(10):1323-1331.  
[6] 李先宽,李赫宇,李帅,等.白藜芦醇研究进展[J].中草药,2016,47(14):2568-2578. LI X K,LI H Y,LI S,et al.Advances in study on resveratrol[J].Chinese Traditional and Herbal Drugs,2016,47(14):2568-2578.(in Chinese)
[7] VELÁSQUEZ D A,MARTÍNEZ G,ROMERO A,et al.The central sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin[J].Diabetes,2011,60(4):1177-1185.  
[8] 董婧,王洋,郭锦晓,等.白藜芦醇强化卤虫对斑马鱼肠道的形态结构和抗氧化能力的影响[J].沈阳农业大学学报,2016,47(4):488-492. DONG J,WANG Y,GUO J X,et al.Effects of resveratrol enriched artemia on intestinal morphology and anti-oxidative capacities of zebrafish (Barchydanio rerio)[J].Journal of Shenyang Agricultural University,2016,47(4):488-492.(in Chinese)
[9] 胡瑶莲,张恒志,陈代文,等.白藜芦醇对生长育肥猪抗氧化能力、空肠黏膜免疫及结肠菌群的影响[J].动物营养学报,2019,31(1):459-468. HU Y L,ZHANG H Z,CHEN D W,et al.Effects of resveratrol on antioxidant capacity,jejunal mucosal immunity and colonic microflora of growing-finishing pigs[J].Chinese Journal of Animal Nutrition,2019,31(1):459-468.(in Chinese)
[10] ERSHAD M,SHIGENAGA M K,BANDY B.Differential protection by anthocyanin-rich bilberry extract and resveratrol against lipid micelle-induced oxidative stress and monolayer permeability in Caco-2 intestinal epithelial cells[J].Food & Function,2021,12(7):2950-2961.  
[11] 龚福来,林雪,王红权.不同维生素C源对吉富罗非鱼生长性能、抗氧化能力和免疫力的影响[J].动物营养学报,2021,33(4):2378-2389. GONG F L,LIN X,WANG H Q.Effects of different vitamin C sources on growth performance,antioxidant capacity and immunity of genetically improved farmed tilapia[J].Chinese Journal of Animal Nutrition,2021,33(4):2378-2389.(in Chinese)
[12] YANG G,JIAN S Q,CAO H Z,et al.Changes in microbiota along the intestine of grass carp (Ctenopharyngodon idella):community,interspecific interactions,and functions[J].Aquaculture,2019,498:151-161.
[13] 闫亚楠,夏斯蕾,田红艳,等.白藜芦醇对高脂胁迫团头鲂抗氧化能力、非特异免疫机能和抗病力的影响[J].水生生物学报,2017,41(1):155-164. YAN Y N,XIA S L,TIAN H Y,et al.Effects of resveratrol supplementation on growth performance,immunity,antioxidant capability and disease resistance of blunt snout bream fed high-fat diet[J].Acta Hydrobiologica Sinica,2017,41(1):155-164.(in Chinese)
[14] 贺艳辉,张红燕,龚赟翀,等.我国罗非鱼养殖品种及养殖发展分析[J].水产养殖,2009,30(2):12-14. HE Y H,ZHANG H Y,GONG Y C,et al.Analysis on species and development of tilapia culture in China[J].Journal of Aquaculture,2009,30(2):12-14.(in Chinese)
[15] 鲁康乐.高脂日粮诱导团头鲂脂肪肝发生机制及黄连素调控的研究[D].博士学位论文.南京:南京农业大学,2014. LU K L.Formation mechanism and regulation berberine for fatty liver induced by high-fat diet in blunt snout bream Megalobrama amblycephala[D].Ph.D.Thesis.Nanjing:Nanjing Agricultural University,2014.(in Chinese)
[16] 闫亚楠.白藜芦醇和槲皮素对高脂诱导团头鲂脂代谢、生长性能以及抗氧化能力的影响[D].硕士学位论文.南京:南京农业大学,2017. YAN Y N.Effects of resveratrol and quercetin on lipid metabolism,growth performance, antioxidant capacity of blunt snout bream (Megalobrama amblycephala) fed high fat diet[D].Master's Thesis.Nanjing:Nanjing Agricultural University,2017.(in Chinese)
[17] 赵志祥,史磊磊,张聪,等.饲料添加白藜芦醇对吉富罗非鱼生长免疫和肝脏结构的影响[J].中国农学通报,2018,34(8):111-117. ZHAO Z X,SHI L L,ZHANG C,et al.Effects of resveratrol on growth performance,immunity and liver microstructure of GIFT (Oreochromis niloticus)[J].Chinese Agricultural Science Bulletin,2018,34(8):111-117.(in Chinese)
[18] 李巍伟.白藜芦醇抑菌作用及其机制研究[D].硕士学位论文.石家庄:河北医科大学,2008. LI W W.Antibacterial effect of resveratrol and mechanism research[D].Master's Thesis.Shijiazhuang:Hebei Medical University,2008.(in Chinese)
[19] 楼允东.组织胚胎学[M].北京:中国农业出版社,1996:101-104. LOU Y D.Histology and embryology[M].Beijing:China Agriculture Press,1996:101-104.(in Chinese)
[20] ANDRES S F,SANTORO M A,MAH A T,et al.Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem,enteroendocrine,and Paneth cell mRNAs[J].American Journal of Physiology:Gastrointestinal and Liver Physiology,2015,308(2):G100-G111.
[21] ZHANG B W,XU Y C,LV H,et al.Intestinal pharmacokinetics of resveratrol and regulatory effects of resveratrol metabolites on gut barrier and gut microbiota[J].Food Chemistry,2021,357:129532.
[22] 唐茂妍,吴海坤.畜禽肠道杯状细胞的作用及其影响因素[J].畜牧产业,2021(2):75-78. TANG M Y,WU H K.The role of intestinal goblet cells in livestock and poultry and its influencing factors[J].Animal Agriculture,2021(2):75-78.(in Chinese)
[23] 于飞,李岩溪,任亚浩,等.白藜芦醇对高脂模型小鼠脂代谢影响[J].中国公共卫生,2010,26(11):1401-1402. YU F,LI Y X,REN Y H,et al.Short-term effects of resveratrol on lipid metabolism in mice with high-fat diet[J].Chinese Journal of Public Health,2010,26(11):1401-1402.(in Chinese)
[24] ZHAO L,CEN F,TIAN F,et al.Combination treatment with quercetin and resveratrol attenuates high fat diet-induced obesity and associated inflammation in rats via the AMPKα1/SIRT1 signaling pathway[J].Experimental and Therapeutic Medicine,2017,14(6):5942-5948.
[25] ELLUL P,BOYER L,GROC L,et al.Interleukin-1β-targeted treatment strategies in inflammatory depression:toward personalized care[J].Acta Psychiatrica Scandinavica,2016,134(6):469-484.  
[26] PAPANICOLAOU D A,WILDER R L,MANOLAGAS S C,et al.The pathophysiologic roles of interleukin-6 in human disease[J].Annals of Internal Medicine,1998,128(2):127-137.  
[27] BAUD V,KARIN M.Signal transduction by tumor necrosis factor and its relatives[J].Trends in Cell Biology,2001,11(9):372-377.  
[28] 杨汉春.动物免疫学[M].2版.北京:中国农业大学出版社,2003:95-108. YANG H C.Animal immunology[M].2nd ed.Beijing:China Agricultural University Press,2003:95-108.(in Chinese)
[29] ZHANG S.The role of transforming growth factor β in T helper 17 differentiation[J].Immunology,2018,155(1):24-35.  
[30] GAITANTZI H,MEYER C,RAKOCZY P,et al.Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis[J].Cell Death & Disease,2018,9(2):51.
[31] PORET J M,SOUZA-SMITH F,MARCELL S J,et al.High fat diet consumption differentially affects adipose tissue inflammation and adipocyte size in obesity-prone and obesity-resistant rats[J].International Journal of Obesity,2018,42(3):535-541.  
[32] 刘继法,胡渊龙,邱占军,等.中药有效成分治疗脓毒症急性肺损伤作用机制研究进展[J].辽宁中医药大学学报,2021,23(1):171-176. LIU J F,HU Y L,QIU Z J,et al.Advances in the pathogenesis of active ingredients of traditional Chinese medicine in the treatment of acute lung injury in sepsis[J].Journal of Liaoning University of Traditional Chinese Medicine,2021,23(1):171-176.(in Chinese)
[33] ANDRADE J M O,PARAÍSO A F,DE OLIVEIRA M V M,et al.Resveratrol attenuates hepatic steatosis in high-fat fed mice by decreasing lipogenesis and inflammation[J].Nutrition,2014,30(7/8):915-919.
[34] YOSHIZAKI T,MILNE J C,IMAMURA T,et al.SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes[J].Molecular and Cellular Biology,2009,29(5):1363-1374.  
[35] PFLUGER P T,HERRANZ D,VELASCO-MIGUEL S,et al.Sirt1 protects against high-fat diet-induced metabolic damage[J].Proceedings of the National Academy of Sciences of the United States of America,2008,105(28):9793-9798.  
[36] 董娇娥,刘洁,胡璇,等.高脂饮食对肠道功能的影响[J].生命的化学,2019,39(6):1098-1106. DONG J E,LIU J,HU X,et al.The effect of high-fat diet on intestinal function[J].Chemistry of Life,2019,39(6):1098-1106.(in Chinese)
[37] STENGEL S,MESSNER B,FALK-PAULSEN M,et al.Regulated proteolysis as an element of ER stress and autophagy:implications for intestinal inflammation[J].Biochimica et Biophysica Acta:Molecular Cell Research,2017,1864(11 Pt B):2183-2190.
[38] YANG J W,TIAN G,CHEN D W,et al.Involvement of PKA signalling in anti-inflammatory effects of chitosan oligosaccharides in IPEC-J2 porcine epithelial cells[J].Journal of Animal Physiology and Animal Nutrition,2018,102(1):252-259.  
[39] SHI L,FANG B,YONG Y H,et al.Chitosan oligosaccharide-mediated attenuation of LPS-induced inflammation in IPEC-J2 cells is related to the TLR4/NF-κB signaling pathway[J].Carbohydrate Polymers,2019,219:269-279.
[40] 瞿秋红.白藜芦醇对猪肠道微生物区系、炎症相关基因和紧密连接蛋白表达的影响研究[D].硕士学位论文.南宁:广西大学,2020. QU Q H.Study on the effect of resveratrol on gut microflora,the expression of the genes related to inflammation and tight junction protein in pigs[D].Master's Thesis.Nanning:Guangxi University,2020.(in Chinese)
[41] CIANCIULLI A,CALVELLO R,CAVALLO P,et al.Modulation of NF-κB activation by resveratrol in LPS treated human intestinal cells results in downregulation of PGE2 production and COX-2 expression[J].Toxicology in Vitro,2012,26(7):1122-1128.