[1] 何玉新,李海燕.犊牛腹泻的类型、流行与诊治措施[J].现代畜牧科技,2016(5):107. HE Y X,LI H Y.Types,prevalence,diagnosis and treatment of calf diarrhea[J].Modern Animal Husbandry Science & Technology,2016(5):107.(in Chinese)
[2] 范勇,胡光荣,王丽娟,等.微藻育种研究进展[J].生物学杂志,2017,34(2):3-8,35. FAN Y,HU G R,WANG L J,et al.Research progress on microalgae breeding[J].Journal of Biology,2017,34(2):3-8,35.(in Chinese)
[3] 李润植,季春丽,崔红利.微藻生物技术助力功能农业[J].山西农业大学学报(自然科学版),2018,38(3):1-12. LI R Z,JI C L,CUI H L.Microalgal biotechnology promotes functional agriculture[J].Journal of Shanxi Agricultural University (Natural Science Edition),2018,38(3):1-12.(in Chinese)
[4] HORROCKS L A,YEO Y K.Health benefits of docosahexaenoic acid (DHA)[J].Pharmacological Research,1999,40(3):211-225.
[5] 黄明发,吴桂苹,焦必宁.二十二碳六烯酸和二十碳五烯酸的生理功能[J].食品与药品,2007,9(2):69-71. HUANG M F,WU G P,JIAO B N.Research advance in physiological function of DHA and EPA[J].Food and Drug,2007,9(2):69-71.(in Chinese)
[6] 阿拉腾珠拉.裂壶藻与乳铁蛋白对哺乳犊牛生长和胃肠道健康的影响[D].硕士学位论文.北京:中国农业科学院,2020. ALATENGZHULA.Effects of
Schizochytrium sp.and lactoferrin on growth and gastrointestinal health of pre-weaning dairy calves[D].Master's Thesis.Beijing:Chinese Academy of Agricultural Sciences,2020.(in Chinese)
[7] MEALE S J,CHAVES A V,HE M L,et al.Dose-response of supplementing marine algae (
Schizochytrium spp.) on production performance,fatty acid profiles,and wool parameters of growing lambs[J].Journal of Animal Science,2014,92(5):2202-2213.
[8] FLAGA J,KORYTKOWSKI Ł,GÓRKA P,et al.The effect of docosahexaenoic acid-rich algae supplementation in milk replacer on performance and selected immune system functions in calves[J].Journal of Dairy Science,2019,102(10):8862-8873.
[9] 李婧.裂殖壶菌利用混合碳源发酵生产DHA的研究[D].硕士学位论文.无锡:江南大学,2015. LI J.A strategy of highly DHA production by
Aurantiochytrium limacinum SR21 with mixed carbon sources[D].Master's Thesis.Wuxi:Jiangnan University,2015.(in Chinese)
[10] ZHANG M L,WU W B,GUO X L,et al.Mathematical modeling of fed-batch fermentation of
Schizochytrium sp. FJU-512 growth and DHA production using a shift control strategy[J].3 Biotech,2018,8(3):162.
[11] LIAN M,HUANG H,REN L J,et al.Increase of docosahexaenoic acid production by
Schizochytrium sp. through mutagenesis and enzyme assay[J].Applied Biochemistry and Biotechnology,2010,162(4):935-941.
[12] 吕小义,付杰,尹佳,等.高产DHA裂壶藻突变株的选育[J].中国酿造,2015,34(4):106-109. LV X Y,FU J,YIN J,et al.Screening of
Schizochytrium limacinum mutant strain with high DHA yield[J].China Brewing,2015,34(4):106-109.(in Chinese)
[13] 龚定芳,熊祎楠,孙佼文,等.常压室温等离子体诱变选育DHA高产菌株[J].中国油脂,2019,44(3):118-122. GONG D F,XIONG Y N,SUN J W,et al.Mutation breeding
Schizochytrium strains producing high-yield DHA via atmospheric and room temperature plasmas[J].China Oils and Fats,2019,44(3):118-122.(in Chinese)
[14] 袁军,赵犇,孙梦玉,等.常压室温等离子体(ARTP)诱变快速选育高产DHA的裂殖壶菌突变株[J].生物技术通报,2015,31(10):199-204. YUAN J,ZHAO B,SUN M Y,et al.Rapid mutation breeding
Schizochytrium strains producing high-yield docosahexenoic acid by atmospheric and room temperature plasmas (ARTP)[J].Biotechnology Bulletin,2015,31(10):199-204.(in Chinese)
[15] ZHAO B,LI Y F,LI C L,et al.Enhancement of
Schizochytrium DHA synthesis by plasma mutagenesis aided with malonic acid and zeocin screening[J].Applied Microbiology and Biotechnology,2018,102(5):2351-2361.
[16] OKUYAMA H,ORIKASA Y,NISHIDA T.Significance of antioxidative functions of eicosapentaenoic and docosahexaenoic acids in marine microorganisms[J].Applied and Environmental Microbiology,2008,74(3):570-574.
[17] ZONG H,ZHAN Y,LI X,et al.A new mutation breeding method for
Streptomyces albulus by an atmospheric and room temperature plasma[J].African Journal of Microbiology Research,2012,6(13):3154-3158.
[18] 李仁民,王菊芳,马爽,等.利用脂肪酸合成酶抑制剂和磷酸香草醛反应筛选高产油脂酵母菌[J].微生物学通报,2008,35(4):545-549. LI R M,WANG J F,MA S,et al.Selection of yeast high in lipids-yield by fatty acid synthetase inhibitor and phosphoric acid-vanillin reaction[J].Microbiology China,2008,35(4):545-549.(in Chinese)
[19] 赵犇.提高
Schizochytrium DHA产量的诱变筛选方法研究及高产机理解析[D].博士学位论文.无锡:江南大学,2018. ZHAO B.Specific mutagenesis and screening methods for breeding higher DHA producer of
Schizochytrium sp. and the related mechanism analysis[D].Ph.D.Thesis.Wuxi:Jiangnan University,2018.(in Chinese)
[20] 王申强.裂殖壶菌产DHA的发酵工艺研究及高产菌株选育[D].硕士学位论文.无锡:江南大学,2013. WANG S Q.Study on DHA fermentation technology by
Schizochytrium limacinum SR21and breeding of high-producing strain[D].Master's Thesis.Wuxi:Jiangnan University,2013.(in Chinese)
[21] MA Y B,WANG Z Y,ZHU M,et al.Increased lipid productivity and TAG content in
Nannochloropsis by heavy-ion irradiation mutagenesis[J].Bioresource Technology,2013,136:360-367.
[22] COOKE M S,EVANS M D,DIZDAROGLU M,et al.Oxidative DNA damage:mechanisms,mutation,and disease[J].FASEB Journal,2003,17(10):1195-1214.
[23] GAUNT L F,BEGGS C B,GEORGHIOU G E.Bactericidal action of the reactive species produced by gas-discharge nonthermal plasma at atmospheric pressure:a review[J].IEEE Transactions on Plasma Science,2006,34(4):1257-1269.
[24] METZ J G,ROESSLER P,FACCIOTTI D,et al.Production of polyunsaturated fatty acids by polyketide synthases in both prokaryotes and eukaryotes[J].Science,2001,293(5528):290-293.
[25] RATLEDGE C.Fatty acid biosynthesis in microorganisms being used for single cell oil production[J].Biochimie,2004,86(11):807-815.
[26] HASSAN H M,SCHRUM L W.Roles of manganese and iron in the regulation of the biosynthesis of manganese-superoxide dismutase in
Escherichia coli[J].FEMS Microbiology Reviews,1994,14(4):315-323.
[27] 许永,臧晓南,徐涤,等.裂殖壶菌诱变筛选的研究[J].中国海洋大学学报(自然科学版),2012,42(12):54-58. XU Y,ZANG X N,XU D,et al.Mutation of
Schizochytrium limacinum and screening of elite mutants[J].Periodical of Ocean University of China,2012,42(12):54-58.(in Chinese)
[28] JAKOBSEN A N,AASEN I M,JOSEFSEN K D,et al.Accumulation of docosahexaenoic acid-rich lipid in thraustochytrid
Aurantiochytrium sp. strain T66:effects of N and P starvation and O2 limitation[J].Applied Microbiology and Biotechnology,2008,80(2):297-306.
[29] CHANG G F,GAO N S,TIAN G W,et al.Improvement of docosahexaenoic acid production on glycerol by
Schizochytrium sp. S31 with constantly high oxygen transfer coefficient[J].Bioresource Technology,2013,142:400-406.
[30] HUANG T Y,LU W C,CHU I M.A fermentation strategy for producing docosahexaenoic acid in
Aurantiochytrium limacinum SR21 and increasing C22:6 proportions in total fatty acid[J].Bioresource Technology,2012,123:8-14.
[31] CHEN W,ZHOU P P,ZHU Y M,et al.Improvement in the docosahexaenoic acid production of
Schizochytrium sp. S056 by replacement of sea salt[J].Bioprocess and Biosystems Engineering,2016,39(2):315-321.
[32] 赵犇,王武,李昌灵,等.EMS-ARTP复合诱变选育高产DHA裂殖壶菌[J].食品与机械,2018,34(2):19-24. ZHAO B,WANG W,LI C L,et al.Enhancement of docosahexaenoic acid production in
Schizochytrium sp. 31 combining ethylmethylsulfone and atmospheric and room temperature plasma treatment[J].Food & Machinery,2018,34(2):19-24.(in Chinese)
京公网安备 11010802041926号