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过瘤胃胆碱和过瘤胃葡萄糖对围产期母羊健康、血清生化指标及产羔性能的影响

  • 涂远璐 ,
  • 汤海江 ,
  • 张凯 ,
  • 贾学敬 ,
  • 白云峰 ,
  • 洪伟
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  • 1. 江苏省农业科学院畜牧研究所, 南京 210014;
    2. 农业部种养结合重点实验室, 南京 210014;
    3. 邳州市小河科技发展有限公司, 徐州 221300;
    4. 上海美农生物科技股份有限公司, 上海 200157
涂远璐(1983—),女,江西南昌人,助理研究员,硕士,从事家畜营养与生态研究。E-mail:121663004@qq.com

收稿日期: 2022-05-25

  网络出版日期: 2022-12-15

基金资助

“十三五”国家重点研发计划"智慧牧场生产关键技术研究与营养"(2019YFE0125600)

Effects of Rumen-Protected Choline and Rumen-Protected Glucose on Health, Serum Biochemical Indices and Lambing Performance of Perinatal Ewes

  • TU Yuanlu ,
  • TANG Haijiang ,
  • ZHANG Kai ,
  • JIA Xuejing ,
  • BAI Yunfeng ,
  • HONG Wei
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  • 1. Institute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China;
    2. Key Laboratory of Crop and Livestock Integrated Farming, Ministry of Agriculture, Nanjing 210014, China;
    3. Xiaohe Technology Co., Ltd., Xuzhou 221300, China;
    4. Shanghai Menon Animal Nutrition Technology Co., Ltd., Shanghai 200157, China

Received date: 2022-05-25

  Online published: 2022-12-15

摘要

本研究旨在评估过瘤胃胆碱(RPC)和过瘤胃葡萄糖(RPG)对围产期母羊能量负平衡及其产羔性能的影响。选取80头湖羊,随机分为4组,每组20头,对照组饲喂基础饲粮,RPG组、RPC组和RPC+RPG组每头每天分别添加15 g RPG、3 g RPC、15 g RPG+3 g RPC。试验期50 d,结果表明:1)各组间妊娠毒血症的发病率无显著差异(P>0.05),但与对照组相比,试验组有提高羔羊断奶成活率的趋势(0.10>P>0.05),且RPC+RPG组羔羊初生重显著提高(P<0.05)。2)与对照组相比,添加RPG显著降低了分娩当天母羊血清中β-羟基丁酸含量(P<0.05),同时血清中总蛋白含量也显著提高(P<0.05),还显著提高了产后10 d时血清甲状腺素(T4)含量(P<0.05),对血清葡萄糖含量影响不显著(P>0.05)。3)与对照组相比,添加RPC对血清葡萄糖和β-羟基丁酸含量影响均不显著(P>0.05),相反还显著提高了分娩当天和产后20 d的血清谷丙转氨酶活性(P<0.05),添加RPC+RPG对血清生化指标无显著交互作用(P>0.05)。综上所述,围产期母羊饲粮中添加15 g/(d·头) RPG有助于缓解能量负平衡,而3 g/(d·头) RPC添加效果不显著,但添加RPC+RPG均可以提升羔羊断奶成活率,提高羔羊初生重。

本文引用格式

涂远璐 , 汤海江 , 张凯 , 贾学敬 , 白云峰 , 洪伟 . 过瘤胃胆碱和过瘤胃葡萄糖对围产期母羊健康、血清生化指标及产羔性能的影响[J]. 动物营养学报, 2022 , 34(12) : 7935 -7944 . DOI: 10.3969/j.issn.1006-267x.2022.12.042

Abstract

The aim of this study was to evaluate the effects of rumen-protected choline (RPC) and rumen- protected glucose (RPG) on negative energy balance and lambing performance of perinatal ewes. A total of 80 Hu sheep were selected and randomly divided into 4 groups with 20 sheep in each group. The control group was fed a basal diet. The RPG group, RPC group and RPC+RPG group were given 15 g RPG, 3 g RPC, 15 g RPG+3 g per day, respectively. The experimental period was 50 days. The results showed as follows:1) there was no significant difference in the incidence of pregnancy toxemia among groups (P>0.05), but the experimental group had a tendency to improve the survival rate of lambs weaning (0.10>P>0.05) and the birth weight of lambs increased significantly (P<0.05). 2) Compared with the control group, adding RPG significantly decreased the β-hydroxybutyric acid (BHBA) content in serum of the ewes on the day of delivery (P<0.05) and the total protein content in the serum also significantly increased (P<0.05), it also significantly increased the content of thyroxine (T4) at 10 days postpartum (P<0.05), but had no significant effect on serum glucose content (P>0.05). 3) Compared with the control group, the addition of RPC had no significant effect on serum glucose and BHBA contents (P>0.05), on the contrary, serum glutamic-pyruvic transaminase activity on the day of delivery and 20 days after delivery were also significantly improved (P<0.05), and the combination of RPC and RPG had no significant interaction on serum biochemical parameters (P>0.05). In conclusion, adding 15 g/d RPG per head to the perinatal ewe diet can help alleviate the negative energy balance, while the addition of 3 g/d of RPC per head has no significant effect, but the addition of RPC and RPG can improve lamb weaning survival rate and increase the birth weight of lambs.

参考文献

[1] 路斌, 毛岩崇, 谭春梅, 等.绵羊妊娠毒血症病例分析[J].中国畜牧业, 2020(17):82-83. LU B, MAO Y C, TAN C M, et al.Case analysis of sheep pregnancy toxemia[J].China Animal Industry, 2020(17):82-83.(in Chinese)
[2] 徐楠.皖北地区羊妊娠毒血症病因调查及生化指标分析[D].硕士学位论文.合肥:安徽农业大学, 2019:41-60. XU N.Investigation on the causes of pregnancy-induced toxemia in sheep in northern Anhui province and analysis of biochemical indicators[D].Master's Thesis.Hefei:Anhui Agricultural University, 2019:41-60.(in Chinese)
[3] 贾学敬, 汤海江, 张凯, 等.围产期母羊妊娠毒血症营养调控研究进展[J].饲料研究, 2020, 43(11):121-124. JIA X J, TANG H J, ZHANG K, et al.Research progress on nutrition regulation of pregnancy toxemia in perinatal ewe[J].Feed Research, 2020, 43(11):121-124.(in Chinese)
[4] 钟未来, 王雪莹, 李元晓, 等.母羊妊娠毒血症发病分子机制研究进展[J].黑龙江畜牧兽医, 2021(17):34-39. ZHONG W L, WANG X Y, LI Y X, et al.Research progress on molecular mechanism of pregnancy toxemia in ewes[J].Heilongjiang Animal Science and Veterinary Medicine, 2021(17):34-39.(in Chinese)
[5] 谭艳婵.绵羊妊娠毒血症的发病机制与治疗方法[J].当代畜禽养殖业, 2020(3):30. TAN Y C.The pathogenesis and treatment of pregnancy toxemia[J].Modern Animal Husbandry, 2020(3):30.(in Chinese)
[6] SCHLUMBOHM C, HARMEYER J.Twin-pregnancy increases susceptibility of ewes to hypoglycaemic stress and pregnancy toxaemia[J].Research in Veterinary Science, 2008, 84(2):286-299.  
[7] 袁耀武, 邱小为, 邢岗.羊妊娠毒血症的防治措施[J].现代畜牧科技, 2022, 88(4):79-80. YUAN Y W, QIU X W, XING G.Prevention and treatment of sheep pregnancy toxemia[J].Modern Animal Husbandry Science & Technology, 2022, 88(4):79-80.(in Chinese)
[8] 张帆, 呙于明, 熊本海.围产期奶牛能量负平衡营养调控研究进展[J].动物营养学报, 2020, 32(7):2966-2974. ZHANG F, GUO Y M, XIONG B H.Research progress on nutritional regulation of negative energy balance in dairy cows during transition period[J].Chinese Journal of Animal Nutrition, 2020, 32(7):2966-2974.(in Chinese)
[9] MCCARTHY C S, DOOLEY B C, BRANSTAD E H, et al.Energetic metabolism, milk production, and inflammatory response of transition dairy cows fed rumen-protected glucose[J].Journal of Dairy Science, 2020, 103(8):7451-7461.  
[10] LI X P, TAN Z L, JIAO J Z, et al.Supplementation with fat-coated rumen-protected glucose during the transition period enhances milk production and influences blood biochemical parameters of liver function and inflammation in dairy cows[J].Animal Feed Science and Technology, 2019, 252:92-102.
[11] 李红宇, 王德香, 黄萌, 等.过瘤胃胆碱调控围产期奶牛营养平衡和机体健康研究进展[J].中国畜牧杂志, 2022, 58(9):87-92. LI H Y, WANG D X, HUANG M, et al.Advances in the regulation of rumen-protected choline on nutrient balance and health in perinatal dairy cows[J].Chinese Journal of Animal Science, 2022, 58(9):87-92.(in Chinese)
[12] HUMER E, BRUGGEMAN G, ZEBELI Q.A meta-analysis on the impact of the supplementation of rumen-protected choline on the metabolic health and performance of dairy cattle[J].Animals:an Open Access Journal From MDPI, 2019, 9(8):566.
[13] 刘春海, 李伟, 孙亚波, 等.过瘤胃组合物对辽宁绒山羊母羊血液指标的影响[J].现代畜牧科技, 2022, 86(2):8-12, 18. LIU C H, LI W, SUN Y B, et al.Effect of rumen bypass composition on the blood index of Liaoning cashmere goat ewes[J].Modern Animal Husbandry Science & Technology, 2022, 86(2):8-12, 18.(in Chinese)
[14] 刘春海, 李伟, 孙亚波, 等.过瘤胃组合物对辽宁绒山羊母羊生产性能的影响[J].现代畜牧科技, 2022, 87(3):1-3. LIU C H, LI W, SUN Y B, et al.Effect of rumen-bypass composition on the performance of Liaoning cashmere goat ewes[J].Modern Animal Husbandry Science & Technology, 2022, 87(3):1-3.(in Chinese)
[15] 赵政, 严同云.包被氯化胆碱对乳山羊繁殖性能、乳成分及瘤胃发酵性能的影响[J].中国饲料, 202120):45-48. ZHAO Z, YAN T Y.Effects of coated choline chloride on reproductive performance, milk composition and rumen fermentation performance of dairy goats[J].China Feed, 2021(20):45-48.(in Chinese)
[16] 张凯, 张志鹏, 白云峰, 等.日粮中添加过瘤胃胆碱对湖羊生长性能和营养物质表观消化率的影响[J].江苏农业科学, 2021, 49(5):137-142. ZHANG K, ZHANG Z P, BAI Y F, et al.Effects of feeding with different proportions of rumen protected choline on growth performance and nutrient apparent digestibility of Hu sheep[J].Jiangsu Agricultural Sciences, 2021, 49(5):137-142.(in Chinese)
[17] 张宏福.动物营养参数与饲养标准[M].2版.北京:中国农业出版社, 2010. ZHANG H F.Nutrition parameters and feeding standard for animals[M].2nd ed.Beijing:China Agriculture Press, 2010.(in Chinese)
[18] 宋玉锡, 白云龙, 钱伟东, 等.肉牛能量负平衡发生风险的预警指标建立[J].动物医学进展, 2019, 40(9):133-136. SONG Y X, BAI Y L, QIAN W D, et al.Establishment of early warning indicators for the risk of negative energy balance in beef cattle[J].Progress in Veterinary Medicine, 2019, 40(9):133-136.(in Chinese)
[19] AFFAN A A, AMIRUL F, GHANI A, et al.Serum biochemical, hormonal and fatty acid profiles during the late gestation of pregnancy ketosis in Boer cross goats[J].Jurnal Ilmu Ternak dan Veteriner, 2019, 23(4):180-188.  
[20] XU W, VAN KNEGSEL A T M, VERVOORT J J M, et al.Prediction of metabolic status of dairy cows in early lactation with on-farm cow data and machine learning algorithms[J].Journal of Dairy Science, 2019, 102(11):10186-10201.  
[21] ADEDEJI T A, OZOJE M O, PETERS S O, et al.Effect of coat color and wattle genes on the morphometric characteristics and scrotal dimensions of traditionally reared West African dwarf (WAD) bucks[J].International Journal of Agriculture Environment and Biotechnolog, 2011, 4(2):157-162.
[22] WANG Y P, CAI M, HUA D K, et al.Metabolomics reveals effects of rumen-protected glucose on metabolism of dairy cows in early lactation[J].Animal Feed Science and Technology, 2020, 269:114620.
[23] 李妍, 薛倩, 高艳霞, 等.瘤胃保护葡萄糖对围产后期荷斯坦奶牛生产性能及血清生化指标的影响[J].畜牧兽医学报, 2016, 47(1):113-119. LI Y, XUE Q, GAO Y X, et al.Effects of rumen-protected glucose on performance and blood biochemical parameters during postpartum period in dairy cows[J].Acta Veterinaria et Zootechnica Sinica, 2016, 47(1):113-119.(in Chinese)
[24] 张凡建, 安立刚, 李丹, 等.产前添加过瘤胃胆碱对围产期奶牛生产性能和肝脏功能的影响[J].中国畜牧杂志, 2020, 56(6):91-95. ZHANG F J, AN L G, LI D, et al.Effects of prepartum supplementation of rumen protected choline on production performance and hepatic function in transition dairy cows[J].Chinese Journal of Animal Science, 2020, 56(6):91-95.(in Chinese)
[25] 孙菲菲.胆碱和蛋氨酸对奶牛围产期营养平衡和机体健康的影响及机制[D].博士学位论文.杨凌:西北农林科技大学, 2017:85-153. SUN F F.Choline and methionine regulate nutrient balance and health of transition dairy cows:responses and potential mechnisms[D].Ph.D.Thesis.Yangling:Northwest A&F University, 2017:85-153.(in Chinese)
[26] LEMASTER C T, TAYLOR R K, RICKS R E, et al.The effects of late gestation maternal nutrient restriction with or without protein supplementation on endocrine regulation of newborn and postnatal beef calves[J].Theriogenology, 2017, 87:64-71.
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