本文旨在探讨壳聚糖锌（CS-Zn）对断奶仔猪生长性能、血清激素和生化指标的影响。选择均重7.25 kg的断奶仔猪120头，随机分为5组（每组3个重复，每个重复8头）。对照组饲喂基础饲粮，试验组饲粮在基础饲粮中分别添加50 mg/kg CS-Zn、100 mg/kg CS-Zn、100 mg/kg硫酸锌（ZnSO4）和3 000 mg/kg氧化锌（ZnO），均以锌计。饲养期35 d。结果表明：1）与对照组和100 mg/kg ZnSO4组相比，饲粮添加100 mg/kg CS-Zn能显著提高断奶仔猪日增重，降低料重比和腹泻率（P＜0.05），但与3 000 mg/kg ZnO组无显著差异（P＞0.05）；2）100 mg/kg CS-Zn组血清胰岛素样生长因子-Ⅰ含量显著高于对照组和100 mg/kg ZnSO4组（P<0.05）；3）与对照组相比，100 mg/kg CS-Zn组血清碱性磷酸酶活性和白蛋白含量均显著升高（P＜0.05），血清尿素氮含量显著降低（P＜0.05）。结果提示，饲粮中添加100 mg/kg CS-Zn能提高断奶仔猪生长性能，降低腹泻率，其效果与添加3 000 mg/kg ZnO相当

This experiment was conducted to study the effects of chitosan-zinc (CS-Zn) on growth performance, serum hormone and biochemical indices of weanling piglets. One hundred and twenty weanling piglets with an average body weight of 7.25 kg were randomly allocated into 5 groups (3 replicates in each group and 8 piglets per replicate) and fed with basal diet (control), basal diet supplemented with 50 mg/kg Zn as CS-Zn, basal diet supplemented with 100 mg/kg Zn as CS-Zn, basal diet supplemented with 100 mg/kg Zn as ZnSO4 or 3 000 mg/kg Zn as ZnO, respectively. Feeding trial lasted for 35 d. The results showed as follows: 1) compared with the control and 100 mg/kg ZnSO4 groups, diet supplemented with 100 mg/kg Zn as CS-Zn could significantly improve average daily gain (P＜0.05), and significantly decrease the ratio of feed to gain and diarrhea rate (P＜0.05), but there was no significant difference between the 100 mg/kg CS-Zn and 3 000 mg/kg ZnO groups (P>0.05); 2) serum insulin-like growth factor-Ⅰ content in the 100 mg/kg CS-Zn group was significantly higher than that of the control and 100 mg/kg ZnSO4 groups (P＜0.05); 3) compared with the control group, serum alkaline phosphatase activity and albumin content in the 100 mg/kg CS-Zn group were significantly improved (P＜0.05), but serum urea nitrogen content in this group was significantly decreased (P＜0.05). These results indicate that diet supplemented with 100 mg/kg Zn as CS-Zn can improve growth performance and decrease diarrhea rate of weanling piglets, and has similar effects on 3 000 mg/kg Zn as ZnO.［Chinese Journal of Animal Nutrition, 2010，22（5）:1355-1360］