Abstract：This experiment studied the effects of dietary linoleic acid to α-linolenic acid ratio (LA/ALA) on growth performance and serum biochemical indices of finishing pig. Ninety Duroc×Landrace×Yorkshire crossbred finishing pigs with an average initial body weight of around 70 kg were divided randomly into 6 groups of 15 pigs (5 replicates in each group, 3 pigs per replicate). Dietary LA/ALA of 32:1, 22:1, 13:1, 9:1, 6:1 and 3:1 were obtained by replacing corm oil with the same amount of linseed oil, respectively. The results showed as follows:1) with the decreasing of dietary LA/ALA, average daily gain (ADG) and average daily feed intake (ADFI) of finishing pigs increased first and then decreased (P<0.05), and 13:1 and 9:1 groups were the highest,respectively; while feed/gain was the lowest in 6:1 group, and significantly lower than that in other groups (P<0.05). 2) The dietary LA/ALA of 3:1 significantly increased serum triglyceride content (P<0.05) and high density lipoprotein cholesterol (HDL-C)/low density lipoprotein cholesterol (LDL-C) increased with the decreasing of dietary LA/ALA (P<0.05). Serum total cholesterol, HDL-C and LDL-C contents had no significant difference among groups (P>0.05). 3) Serum immuneglobulin M content significantly increased with the decreasing of dietary LA/ALA (P<0.05). Serum lysozyme activity was the highest in 13:1 group, and significantly higher than that in 32:1, 6:1 and 3:1 groups (P<0.05). Serum interleukin (IL)-2 and IL-6 contents had no significant difference among groups (P>0.05). In conclusion, reducing dietary LA/ALA can improve growth performance, lipid metabolism and immune function of finishing pigs to a certain extent.
陈静, 刘显军, 王彤, 李建涛, 何洋, 杨营, 李海东, 程奇. 饲粮必需脂肪酸组成对育肥猪生长性能和血清生化指标的影响[J]. 动物营养学报, 2019, 31(8): 3543-3550.
CHEN Jing, LIU Xianjun, WANG Tong, LI Jiantao, HE Yang, YANG Ying, LI Haidong, CHENG Qi. Effects of Dietary Essential Fatty Acid Composition on Growth Performance and Serum Biochemical Indices of Finishing Pigs. Chinese Journal of Animal Nutrition, 2019, 31(8): 3543-3550.
YAND L G,SONG Z X,YIN H,et al.Low n-6/n-3 PUFA ratio improves lipid metabolism,inflammation,oxidative stress and endothelial function in rats using plant oils as n-3 fatty acid source[J].Lipids,2016,51(1):49-59.
[14]
GEELEN M J H,SCHOOTS W J,BIJLEVELD C,et al.Dietary medium-chain fatty acids raise and (n-3) polyunsaturated fatty acids lower hepatic triacylglycerol synthesis in rats[J].Journal of Nutrition,1995,125(10):2449-2456.
[17]
MA J,WANG J,ZHANG D,et al.Estimation of optimum docosahexaenoic to eicosapentaenoic acid ratio (DHA/EPA) for juvenile starry flounder,Platichthys stellatus[J].Aquaculture,2014,433:105-114.
[10]
DE TONNAC A,KARIM-LUISSET S,MOUROT J.Effect of different dietary linseed sources on fatty acid composition in pig tissues[J].Livestock Science,2017,203:124-131.
CHEN C Y,CHEN J S,WANG S Q,et al.Effects of different dietary ratios of linolenic to linoleic acids or docosahexaenoic to eicosapentaenoic acids on the growth and immune indices in grouper,Epinephelus coioides[J].Aquaculture,2017,473:153-160.
[12]
PAULINO R R,PEREIRA R T,FONTES T V,et al.Optimal dietary linoleic acid to linolenic acid ratio improved fatty acid profile of the juvenile tambaqui (Colossoma macropomum)[J].Aquaculture,2018,488:9-16.
[15]
RIDKER P M,RIFAI N,ROSE L,et al.Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events[J].New England Journal of Medicine,2002,347(20):1557-1565.
[1]
LIU W C,KIM I H.Effects of different dietary n-6:n-3 PUFA ratios on growth performance,blood lipid profiles,fatty acid composition of pork,carcass traits and meat quality in finishing pigs[J].Annals of Animal Science,2018,18(1):143-154.
[3]
DE OLIVEIRA M R,NABAVI S F,NABAVI S M,et al.Omega-3 polyunsaturated fatty acids and mitochondria,back to the future[J].Trends in Food Science & Technology,2017,67:76-92.
[8]
DUAN Y H,LI F N,LI L L,et al.n-6:n-3 PUFA ratio is involved in regulating lipid metabolism and inflammation in pigs[J].British Journal Nutrition,2014,111(3):445-451.
[9]
LI F N,DUAN Y H,LI Y H.Effects of dietary n-6:n-3 PUFA ratio on fatty acid composition,free amino acid profile and gene expression of transporters in finishing pigs[J].British Journal of Nutrition,2015,113(5):739-748.
[11]
TILTON S L,MILLER P S,LEWIS A J,et al.Addition of fat to the diets of lactating sows:Ⅰ.Effects on milk production and composition and carcass composition of the litter at weaning[J].Journal Animal Science,1999,77(9):2491-2500.
[16]
CHEN G F,LIU Y,JIANG J,et al.Effect of dietary arginine on the immune response and gene expression in head kidney and spleen following infection of Jian carp with Aeromonas hydrophila[J].Fish & Shellfish Immunology,2015,44(1):195-202.
[18]
LI Q L,TIAN Z X,WANG M H,et al.Luteoloside attenuates neuroinflammation in focal cerebral ischemia in rats via regulation of the PPARγ/Nrf2/NF-κB signaling pathway[J].International Immunopharmacology,2019,66:309-316.
[19]
MAYER K,MEYER S,REINHOLZ-MUHLY M.Short-time infusion of fish oil-based lipid emulsions,approved for parenteral nutrition,reduces monocyte proinflammatory cytokine generation and adhesive interaction with endothelium in humans[J].The Journal of Immunology,2003,171(9):4837-4843.
