Abstract：This experiment was conducted to evaluate the effects of Pediococcus acidilactici on growth performance, fecal microbiota, serum biochemical and immune indexes of growing pigs. A total of 140 "Landrace×Yorkshire" crossbred growing pigs with an average body weight of (23.21±0.84) kg were divided into 2 groups: control group and experimental group. Each group had 5 replicates with 14 pigs per replicate. Pigs in the control group were fed a basal diet, and those in the experimental group were fed the basal diet supplemented with 2.70×109 CFU/kg Pediococcus acidilactici freeze-drying preparation. The adjustment period was 5 d, and the experiment period was 34 d. The results showed that compared with the control group: 1) the average daily gain (ADG) of growing pigs was increased by 5.64% (P<0.05), and the feed/gain (F/G) was decreased by 4.62% (P<0.05) in the experimental group; 2) the number of fecal lactic acid bacteria of growing pigs was significantly increased (P<0.05), and the numbers of Escherichia coli and Staphylococcus aureus were significantly decreased (P<0.05) in the experimental group; 3) Pediococcus acidilactici increased the fecal microbiota species richness, the proportions of Firmicutes, Prevotella, Megasphaera and Lactobacillus were also increased in the experimental group; 4) the contents of serum total protein (TP), globulin (GLB), immunoglobulin G (IgG) and immunoglobulin A (IgA) were increased by 13.45% (P<0.05), 14.91% (P<0.05), 20.91% (P<0.05) and 44.00% (P<0.05), and the contents of serum urea nitrogen (UN) and haptoglobin (HP) were decreased by 19.46% (P<0.05) and 38.71% (P<0.05) in the experimental group, respectively. The results indicate that dietary supplemented with 2.70×109 CFU/kg Pediococcus acidilactici can improve the intestinal microbiota composition, enhance the immune function and improve the growth performance of growing pigs.
刘辉, 季海峰, 王四新, 张董燕, 王晶, 张伟, 王雅民. 乳酸片球菌对生长猪生长性能、粪便菌群、血清生化和免疫指标的影响[J]. 动物营养学报, 2020, 32(6): 2558-2566.
LIU Hui, JI Haifeng, WANG Sixin, ZHANG Dongyan, WANG Jing, ZHANG Wei, WANG Yamin. Effects of Pediococcus acidilactici on Growth Performance, Fecal Microbiota, Serum Biochemical and Immune Indexes of Growing Pigs. Chinese Journal of Animal Nutrition, 2020, 32(6): 2558-2566.
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