Effects of Benzoic Acid on Growth Performance, Diarrhea Rate and Intestinal Flora of Weaned Piglets
WEN Xiaolu1, ZHENG Chuntian1, YANG Xuefen1, JIANG Zongyong1, GAO Kaiguo1, ZHANG Jie2, WANG Li1
1. State Key Laboratory of Livestock and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
2. Guangdong Engineering Technology Rresearch Center of Pig Breeding, Qingyuan Longfa Pig Breeding Co., Ltd., Qingyuan 513058, China
Abstract：The objective of this study was to investigate the effects of dietary benzoic acid on growth performance, diarrhea rate and intestinal flora of weaned piglets. A total of 72 Duroc×Landrace×Yorkshire weaned piglets at aged of 21 days were allotted to control group and benzoic acid group according to body weight with 6 replicates, and 6 pigs (3 barrows and 3 gilts) per replicate. The experiment lasted for 42 days, which was divided into three stages: days 1 to 14, days 15 to 28 and days 29 to 42. The control group were fed a basal diet, while benzoic acid group were fed the basal diet supplemented with 5 000 mg/kg benzoic acid. The results showed that compared with control group, 1) dietary supplementation of 5 000 mg/kg benzoic acid significantly increased the body weight of piglets on day 14 (P<0.05), the average daily gain from days 1 to 14 was significantly increased (P<0.05), and the feed to gain ratio of piglets from days 29 to 42 and days 1 to 42 after weaning was significantly decreased (P<0.05); 2) diarrhea rate and fecal score of piglets from days 1 to 14, days 15 to 28, days 29 to 42 and days 1 to 42 after weaning were significantly decreased (P<0.05); 3) the number of Bacillus in ileum, cecum and colon were significantly reduced on day 14 (P<0.05), the number of Bacillus in cecum was significantly reduced on day 42 (P<0.05), the number of total bacteria in colon, cecum and colon was significantly reduced on day 14 (P<0.05), and the number of Lactobacillus in ileum was significantly increased on day 42 (P<0.05). There was a tendency to increase the number of Lactobacillus in ileum on day 14 (P=0.083), and to decrease the number of E.coli in colon on day 42 (P=0.065). In conclusion, dietary supplemented 5 000 mg/kg benzoic acid significantly reduce the diarrhea rate and fecal score of piglets, inhibit the growth of intestinal bacteria, and improve the growth performance of piglets.
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